{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T03:22:38Z","timestamp":1760239358026,"version":"build-2065373602"},"reference-count":35,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2020,11,6]],"date-time":"2020-11-06T00:00:00Z","timestamp":1604620800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Fonds de la Recherche Scientifique","award":["31248729"],"award-info":[{"award-number":["31248729"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animals"],"abstract":"<jats:p>The strategy of improving the growth and health of piglets through maternal fiber diet intervention has attracted increasing attention. Therefore, 15 sows were conducted to a wheat bran (WB) group, in which the sows\u2019 diets included 25% of WB in gestation and 14% in lactation, and a control (CON) group, in which the sows\u2019 diets at all stages of reproduction did not contain WB. The results show that maternal high WB intervention seems not to have an impact on the growth of the offspring or the villus height of the duodenum, and the ratio of villi\/crypts in the duodenum and jejunum were all higher in piglets born from WB sows, which may indicate that WB piglets had a larger absorption area and capacity for nutrients. The peroxisome proliferator-activated receptor gamma (PPAR\u03b3) and interleukin 6 (IL6) expression levels were notably upregulated in the ileal mucosa of WB piglets, while no immune-related genes in the colonic mucosa were affected by the maternal WB supplementation. In conclusion, adding a high proportion of wheat bran to the sow\u2019s gestation and lactation diet can affect the intestinal architecture and the expression of some inflammation genes, to some extent, in the ileal mucosa in the progeny.<\/jats:p>","DOI":"10.3390\/ani10112051","type":"journal-article","created":{"date-parts":[[2020,11,6]],"date-time":"2020-11-06T09:03:04Z","timestamp":1604653384000},"page":"2051","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Effects of Wheat Bran Applied to Maternal Diet on the Intestinal Architecture and Immune Gene Expression in Suckling Piglets"],"prefix":"10.3390","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5112-0262","authenticated-orcid":false,"given":"Julie","family":"Leblois","sequence":"first","affiliation":[{"name":"Association Wallonne de l\u2019\u00c9levage Asbl (AW\u00c9), 5590 Ciney, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3336-7426","authenticated-orcid":false,"given":"Yuping","family":"Zhang","sequence":"additional","affiliation":[{"name":"Precision Livestock and Nutrition Laboratory, TERRA Teaching and Research Centre, Gembloux Agro-Bio Tech, University of Li\u00e8ge, 5030 Gembloux, Belgium"},{"name":"State Key Laboratory of Animal Nutrition, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9","family":"Wavreille","sequence":"additional","affiliation":[{"name":"Precision Livestock and Nutrition Laboratory, TERRA Teaching and Research Centre, Gembloux Agro-Bio Tech, University of Li\u00e8ge, 5030 Gembloux, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julie","family":"Uerlings","sequence":"additional","affiliation":[{"name":"Precision Livestock and Nutrition Laboratory, TERRA Teaching and Research Centre, Gembloux Agro-Bio Tech, University of Li\u00e8ge, 5030 Gembloux, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3855-8141","authenticated-orcid":false,"given":"Martine","family":"Schroyen","sequence":"additional","affiliation":[{"name":"Precision Livestock and Nutrition Laboratory, TERRA Teaching and Research Centre, Gembloux Agro-Bio Tech, University of Li\u00e8ge, 5030 Gembloux, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3299-1510","authenticated-orcid":false,"given":"Ester Ar\u00e9valo","family":"Sureda","sequence":"additional","affiliation":[{"name":"Precision Livestock and Nutrition Laboratory, TERRA Teaching and Research Centre, Gembloux Agro-Bio Tech, University of Li\u00e8ge, 5030 Gembloux, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9883-9047","authenticated-orcid":false,"given":"H\u00e9l\u00e8ne","family":"Soyeurt","sequence":"additional","affiliation":[{"name":"Laboratory of Statistics, Informatics and Modelling Applied to Bioengineering, TERRA Teaching and Research Centre, Gembloux Agro-Bio Tech, University of Li\u00e8ge, 5030 Gembloux, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6733-4334","authenticated-orcid":false,"given":"Fr\u00e9d\u00e9ric","family":"Dehareng","sequence":"additional","affiliation":[{"name":"Valorisation of Agricultural Products Department, Walloon Agricultural Research Centre, 5030 Gembloux, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3313-485X","authenticated-orcid":false,"given":"Cl\u00e9ment","family":"Grelet","sequence":"additional","affiliation":[{"name":"Valorisation of Agricultural Products Department, Walloon Agricultural Research Centre, 5030 Gembloux, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9918-277X","authenticated-orcid":false,"given":"Isabelle P.","family":"Oswald","sequence":"additional","affiliation":[{"name":"Toxalim Research Centre in Food Toxicology, University of Toulouse, INRA, ENVT, INP-Purpan, UPS, 31027 Toulouse, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bing","family":"Li","sequence":"additional","affiliation":[{"name":"New Hope Liuhe Co., Ltd., Qingdao 266000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00e9r\u00f4me","family":"Bindelle","sequence":"additional","affiliation":[{"name":"Precision Livestock and Nutrition Laboratory, TERRA Teaching and Research Centre, Gembloux Agro-Bio Tech, University of Li\u00e8ge, 5030 Gembloux, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongfu","family":"Zhang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Animal Nutrition, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nadia","family":"Everaert","sequence":"additional","affiliation":[{"name":"Precision Livestock and Nutrition Laboratory, TERRA Teaching and Research Centre, Gembloux Agro-Bio Tech, University of Li\u00e8ge, 5030 Gembloux, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2020,11,6]]},"reference":[{"key":"ref_1","first-page":"405","article-title":"The role of wheat non-starch polysaccharides in broiler nutrition","volume":"44","author":"Annison","year":"1993","journal-title":"Aust. 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