{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T00:36:17Z","timestamp":1790987777616,"version":"4.1.0"},"reference-count":29,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2021,1,12]],"date-time":"2021-01-12T00:00:00Z","timestamp":1610409600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100008530","name":"European Regional Development Fund","doi-asserted-by":"publisher","award":["n19005"],"award-info":[{"award-number":["n19005"]}],"id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"publisher"}]},{"name":"01.02.01 de Transfer\u00e8ncia Tecnol\u00f2gica del Programa de desenvolupament rural de Catalunya 2014-2020","award":["19005"],"award-info":[{"award-number":["19005"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animals"],"abstract":"<jats:p>Twin pregnancies are undesirable in dairy cattle as they dramatically compromise cow lifespan and, consequently, herd economy. Clinical problems in cows arise from the time of pregnancy diagnosis to pregnancy loss, abortion, or parturition. The drainage of co-dominant follicles in cows with two or more follicles at insemination prevents twin pregnancy. The objective of this study was to compare the effectiveness of draining the smaller of two follicles through a simplified maneuver not requiring ultrasonography in cows in their third or more lactation, and then inducing ovulation immediately before artificial insemination (AI) with GnRH or human chorionic gonadotrophin (hCG). Animals were monitored by ultrasound at AI and randomly assigned to the groups: follicular drainage and treatment with GnRH (Deph; n = 60), follicular drainage and treatment with hCG (hCG; n = 60), and non-drainage (ND; n = 60) as control cows. On the basis of odds ratios, cows treated with hCG were 2.1 times more likely to become pregnant than control animals. Our results reveal the efficacy of hCG treatment at AI in cows with two follicles of pre-ovulatory size subjected to a simple follicular drainage procedure.<\/jats:p>","DOI":"10.3390\/ani11010169","type":"journal-article","created":{"date-parts":[[2021,1,12]],"date-time":"2021-01-12T14:28:53Z","timestamp":1610461733000},"page":"169","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Inducing Ovulation with hCG Improves Fertility Outcomes of Co-Dominant Follicle Drainage to Avoid Twin Pregnancy in Dairy Cows"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5756-6513","authenticated-orcid":false,"given":"Irina","family":"Garcia-Ispierto","sequence":"first","affiliation":[{"name":"Agrotecnio Centre, University of Lleida, 25198 Lleida, Spain"},{"name":"Department of Animal Science, University of Lleida, 25198 Lleida, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00f2nica","family":"Pando","sequence":"additional","affiliation":[{"name":"Granja Allu\u00e9, Sucs, 25113 Lleida, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00f2nica","family":"Llobera-Balcells","sequence":"additional","affiliation":[{"name":"Department of Animal Science, University of Lleida, 25198 Lleida, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,1,12]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.anireprosci.2005.03.003","article-title":"Genetic and environmental factors influencing first service conception rate and late embryonic\/foetal mortality in low fertility dairy herds","volume":"91","author":"Grimard","year":"2006","journal-title":"Anim. 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