{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:30:34Z","timestamp":1787027434301,"version":"build-2736575974"},"reference-count":35,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2021,1,16]],"date-time":"2021-01-16T00:00:00Z","timestamp":1610755200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animals"],"abstract":"<jats:p>Producers and veterinarians are considered responsible for improving animal welfare, as they are responsible for implementing practices that directly impact the animal\u2019s well-being. Most husbandry procedures performed in cattle do not include pain mitigation, and understanding challenges faced by these stakeholders to use analgesics is key in improving on-farm pain management strategies. Therefore, the objectives of this study were to explore producer and veterinarian perspectives on pain management practices by (1) exploring inquires received by Food Animal Residue Avoidance Databank (FARAD) regarding analgesic use in cattle and (2) using a survey instrument to identify factors that impact pain management implementation in the US cattle industry. Albeit analgesia use increased in the past ten years for some producers and the majority of veterinarians, administering analgesics for pain management on US cattle farms remains a challenge. From a producer perspective, drug cost, availability and logistics for administration. From a veterinarian perspective, lack of Food and Drug Administration (FDA) products hinders the support of on-farm protocols requiring extra-label drug use. Future steps to improve analgesic use on-farm include identifying and approving drugs that demonstrate efficacy for managing pain in cattle and disseminating educational resources to support stakeholders in both the implementation and drug withdrawal process.<\/jats:p>","DOI":"10.3390\/ani11010209","type":"journal-article","created":{"date-parts":[[2021,1,18]],"date-time":"2021-01-18T05:17:34Z","timestamp":1610947054000},"page":"209","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Producer and Veterinarian Perspectives towards Pain Management Practices in the US Cattle Industry"],"prefix":"10.3390","volume":"11","author":[{"given":"Ivelisse","family":"Robles","sequence":"first","affiliation":[{"name":"Department of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7040-9686","authenticated-orcid":false,"given":"Andreia G.","family":"Arruda","sequence":"additional","affiliation":[{"name":"Department of Veterinary Preventive Medicine, College of Veterinary Medicine, The Ohio State University, Columbus, OH 43210, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6570-4928","authenticated-orcid":false,"given":"Emma","family":"Nixon","sequence":"additional","affiliation":[{"name":"Department of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth","family":"Johnstone","sequence":"additional","affiliation":[{"name":"Department of Animal Sciences, Colorado State University, Fort Collins, CO 80521, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8197-5437","authenticated-orcid":false,"given":"Brooklyn","family":"Wagner","sequence":"additional","affiliation":[{"name":"Department of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0737-9899","authenticated-orcid":false,"given":"Lily","family":"Edwards-Callaway","sequence":"additional","affiliation":[{"name":"Department of Animal Sciences, Colorado State University, Fort Collins, CO 80521, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald","family":"Baynes","sequence":"additional","affiliation":[{"name":"Department of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1802-3991","authenticated-orcid":false,"given":"Johann","family":"Coetzee","sequence":"additional","affiliation":[{"name":"Department of Anatomy and Physiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS 66506, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6005-5666","authenticated-orcid":false,"given":"Monique","family":"Pairis-Garcia","sequence":"additional","affiliation":[{"name":"Department of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,1,16]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1080\/1523908X.2010.528882","article-title":"Entrapped in group solidarity? Animal welfare, the ethical positions of farmers and the difficult search for alternatives","volume":"12","year":"2010","journal-title":"J. Environ. Pol. Plan."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1007\/s10806-014-9523-x","article-title":"Animal welfare concerns and values of stakeholders within the dairy industry","volume":"28","author":"Ventura","year":"2015","journal-title":"J. Agric. Environ. Ethics."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"10161","DOI":"10.3168\/jds.2016-11270","article-title":"Practices for the disbudding and dehorning of dairy calves by veterinarians and dairy producers in Ontario, Canada","volume":"99","author":"Winder","year":"2016","journal-title":"J. Dairy Sci."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1093\/af\/vfx006","article-title":"Perspectives of farmers and veterinarians concerning dairy cattle welfare","volume":"8","author":"Sumner","year":"2018","journal-title":"Anim. Front."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/0168-1591(95)00635-4","article-title":"Assessment of acute and chronic pain after different methods of castration of calves","volume":"46","author":"Molony","year":"1995","journal-title":"Appl. Anim. Behav. Sci."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.applanim.2011.10.016","article-title":"A review of pain assessment techniques and pharmacological approaches to pain relief after bovine castration: Practical implications for cattle production within the United States","volume":"135","author":"Coetzee","year":"2011","journal-title":"Appl. Anim. Behav. Sci."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"4340","DOI":"10.3168\/jds.2012-6274","article-title":"Effect of castration method on neurohormonal and electroencephalographic stress indicators in Holstein calves of different ages","volume":"96","author":"Dockweiler","year":"2013","journal-title":"J. Dairy Sci"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"2450","DOI":"10.3168\/jds.2009-2813","article-title":"The effect of meloxicam on behavior and pain sensitivity of dairy calves following cautery dehorning with a local anesthetic","volume":"93","author":"Heinrich","year":"2010","journal-title":"J. Dairy Sci."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1139\/cjas-2019-0031","article-title":"Key animal welfare issues in commercially raised dairy calves: Social environment, nutrition, and painful procedures","volume":"99","author":"Costa","year":"2019","journal-title":"Can. J. Anim. Sci."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"10361","DOI":"10.3168\/jds.2018-14987","article-title":"The effect of disbudding age on healing and pain sensitivity in dairy calves","volume":"101","author":"Adcock","year":"2018","journal-title":"J. Dairy Sci."},{"key":"ref_11","doi-asserted-by":"crossref","unstructured":"Coetzee, J.F., Mosher, R.A., KuKanich, B., Gehring, R., Robert, B., Reinbold, J.B., and White, B.J. (2012). Pharmacokinetics and effect of intravenous meloxicam in weaned Holstein calves following scoop dehorning without local anesthesia. BMC Vet. Res., 8.","DOI":"10.1186\/1746-6148-8-153"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"5194","DOI":"10.3168\/jds.2012-6251","article-title":"The effect of timing of oral meloxicam administration on physiological responses in calves after cautery dehorning with local anesthesia","volume":"96","author":"Allen","year":"2013","journal-title":"J. Dairy Sci."},{"key":"ref_13","doi-asserted-by":"crossref","unstructured":"Coetzee, J.F., Nutsch, A.L., Barbur, L.A., and Bradburn, R.M. (2010). A survey of castration methods and associated livestock management practices performed by bovine veterinarians in the United States. BMC Vet. Res., 6.","DOI":"10.1186\/1746-6148-6-12"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"755","DOI":"10.2460\/javma.238.6.755","article-title":"Analgesic drug administration and attitudes about analgesia in cattle among bovine practitioners in the United States","volume":"238","author":"Fajt","year":"2011","journal-title":"J. Am. Vet."},{"key":"ref_15","unstructured":"FOI (2020, December 15). Freedom of Information Summary, Available online: https:\/\/animaldrugsatfda.fda.gov\/adafda\/app\/search\/public\/document\/downloadFoi\/1944."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"197","DOI":"10.2460\/javma.258.2.197","article-title":"Survey investigating current attitudes towards use of pain mitigation practices in beef and dairy cattle in the US by veterinarians and producers","volume":"258","author":"Johnstone","year":"2021","journal-title":"J. Am. Vet. Med. Assoc."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1111\/j.1467-2995.2010.00573.x","article-title":"Effect of sub-anesthetic xylazine and ketamine (\u2018ketamine stun\u2019) administered to calves immediately prior to castration","volume":"37","author":"Coetzee","year":"2010","journal-title":"Vet. Anaesth. Analg."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.applanim.2015.08.023","article-title":"Pain evaluation in dairy cattle","volume":"171","author":"Gleerup","year":"2015","journal-title":"Appl. Anim. Behav. Sci."},{"key":"ref_19","doi-asserted-by":"crossref","unstructured":"Remnant, J.G., Tremlett, A., Huxley, J.N., and Hudson, C.D. (2017). Clinician attitudes to pain and use of analgesia in cattle: Where are we 10 years on?. Vet. Rec.","DOI":"10.1136\/vr.104428"},{"key":"ref_20","unstructured":"Dohoo, I., Martin, W., and Stryhn, H. (2009). Veterinary Epidemiologic Research, VER Inc."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1007\/s10806-016-9615-x","article-title":"A systematic review of public attitudes, perceptions and behaviours towards production diseases associated with farm animal welfare","volume":"29","author":"Clark","year":"2017","journal-title":"J. Agric. Environ. Ethics."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"1596","DOI":"10.2460\/javma.2003.223.1596","article-title":"Evaluation of the advisory services provided by the Food Animal Residue Avoidance Databank","volume":"223","author":"Wang","year":"2003","journal-title":"JAVMA"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.2460\/javma.250.10.1131","article-title":"Guide to FARAD resources: Historical and future perspectives","volume":"250","author":"Riviere","year":"2017","journal-title":"JAVMA"},{"key":"ref_24","unstructured":"(2020, December 15). Doing Enough for Disbudding Pain. Available online: https:\/\/hoards.com\/article-27171-doing-enough-for-disbudding-pain.html."},{"key":"ref_25","unstructured":"(2020, December 15). AABP Updates Dehorning Guidelines | Drovers. Available online: https:\/\/www.drovers.com\/news\/aabp-updates-dehorning-guidelines."},{"key":"ref_26","unstructured":"(2020, December 15). No Flunixin for Pain Relief. Available online: https:\/\/hoards.com\/blog-19997-no-flunixin-for-pain-relief.html."},{"key":"ref_27","unstructured":"FDA (2020, December 15). Current Drug Shortages, Available online: https:\/\/www.fda.gov\/animal-veterinary\/product-safety-information\/current-drug-shortages."},{"key":"ref_28","unstructured":"APHIS (2020, December 15). Dairy 2014 Health and Management Practices on U.S. Dairy Operations, Available online: https:\/\/www.aphis.usda.gov\/animal_health\/nahms\/dairy\/downloads\/dairy14\/Dairy14_dr_PartIII.pdf."},{"key":"ref_29","unstructured":"CROPP (2020, December 15). Animal Care Program. Available online: https:\/\/www.farmers.coop\/sites\/default\/files\/downloads\/cropp_animal_care_standards_010118.pdf."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"5265","DOI":"10.3168\/jds.2013-7746","article-title":"The impact of 3 strategies for incorporating polled genetics into a dairy cattle breeding program on the overall herd genetic merit","volume":"97","author":"Spurlock","year":"2014","journal-title":"J. Dairy Sci."},{"key":"ref_31","first-page":"949","article-title":"Stockperson attitudes toward pig euthanasia","volume":"95","author":"Rault","year":"2017","journal-title":"J. Anim. Sci."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1093\/tas\/txy015","article-title":"Caretaker attitudes toward swine euthanasia1","volume":"2","author":"Campler","year":"2018","journal-title":"Transl. Anim. Sci."},{"key":"ref_33","doi-asserted-by":"crossref","unstructured":"Balzani, A., and Hanlon, A. (2020). Factors that Influence Farmers\u2019 Views on Farm Animal Welfare: A Semi-Systematic Review and Thematic Analysis. Animals, 10.","DOI":"10.3390\/ani10091524"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1136\/vr.159.20.662","article-title":"Current attitudes of cattle practitioners to pain and the use of analgesics in cattle","volume":"159","author":"Huxley","year":"2006","journal-title":"Vet. Rec."},{"key":"ref_35","doi-asserted-by":"crossref","unstructured":"Wagner, B., Royal, K., Park, R., and Pairis-Garcia, M. (2020). Identifying Barriers to Implementing Pain Management for Piglet Castration: A Focus Group of Swine Veterinarians. Animals, 10.","DOI":"10.3390\/ani10071202"}],"container-title":["Animals"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2076-2615\/11\/1\/209\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T05:11:56Z","timestamp":1760159516000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2076-2615\/11\/1\/209"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1,16]]},"references-count":35,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2021,1]]}},"alternative-id":["ani11010209"],"URL":"https:\/\/doi.org\/10.3390\/ani11010209","relation":{},"ISSN":["2076-2615"],"issn-type":[{"value":"2076-2615","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,1,16]]}}}