{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T04:31:01Z","timestamp":1775017861248,"version":"3.50.1"},"reference-count":21,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2021,4,12]],"date-time":"2021-04-12T00:00:00Z","timestamp":1618185600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animals"],"abstract":"<jats:p>Nephrosplenic space (NSS) ablation has been demonstrated to be an effective technique for prevention of left dorsal displacement of the large colon and multiple laparoscopic techniques, among which ablation with mesh or with a barbed suture, have been proposed. Our objective was to compare two laparoscopic techniques for closure of the NSS in twenty-eight horses diagnosed with nephrosplenic entrapment. Medical records of horses that had laparoscopic NSS ablation in two referral centers between 2017\u20132019 were retrieved. Duration of surgery, complications, and short- and long-term follow-up information were collected and compared. Costs were also calculated and compared. All horses met the inclusion criteria: 9 had NSS ablation with a mesh implant (group M), 19 with barbed suture material (group B). One horse in group B had recurrent colic after discharge. At control laparoscopy after 5 months, the NSS resulted in still not being ablated because of a failure of the suture. In group M, three horses had recurrent colic. One was successfully treated medically, one died of unknown causes and the third required a second laparoscopic suturing at 3\u20136 months because of failure of the mesh implant. The mean time of surgery and costs were lower in group B compared to group M. The barbed suture technique was faster, more cost-effective and had a lower complication rate than the mesh implant.<\/jats:p>","DOI":"10.3390\/ani11041096","type":"journal-article","created":{"date-parts":[[2021,4,12]],"date-time":"2021-04-12T11:05:06Z","timestamp":1618225506000},"page":"1096","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Comparison of Mesh and Barbed Suture for Laparoscopic Nephrosplenic Space Ablation in Horses"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1803-1513","authenticated-orcid":false,"given":"Rodolfo","family":"Gialletti","sequence":"first","affiliation":[{"name":"Department of Veterinary Sciences, University of Turin, 10095 Grugliasco, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7774-9920","authenticated-orcid":false,"given":"Sara","family":"Nannarone","sequence":"additional","affiliation":[{"name":"Department of Veterinary Sciences, University of Turin, 10095 Grugliasco, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1402-8261","authenticated-orcid":false,"given":"Marco","family":"Gandini","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine, University of Perugia, 06126 Perugia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4804-3870","authenticated-orcid":false,"given":"Anna","family":"Cerullo","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine, University of Perugia, 06126 Perugia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alice","family":"Bertoletti","sequence":"additional","affiliation":[{"name":"Department of Veterinary Sciences, University of Turin, 10095 Grugliasco, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicola","family":"Scilimati","sequence":"additional","affiliation":[{"name":"Department of Veterinary Sciences, University of Turin, 10095 Grugliasco, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gessica","family":"Giusto","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine, University of Perugia, 06126 Perugia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,4,12]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1111\/vsu.12520","article-title":"Use of a Barbed Knotless Suture for Laparoscopic Ablation of the Nephrosplenic Space in 8 Horses","volume":"45","author":"Albanese","year":"2016","journal-title":"Vet. 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Surg."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1111\/vsu.12549","article-title":"Laparoscopic Closure of the Nephrosplenic Space in Horses with Nephrosplenic Colonic Entrapment: Factors Associated with Survival and Colic Recurrence","volume":"45","author":"Nelson","year":"2016","journal-title":"Vet. Surg."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"431","DOI":"10.2460\/javma.250.4.431","article-title":"Laparoscopic nephrosplenic space ablation with barbed suture in eight horses","volume":"250","author":"Gandini","year":"2017","journal-title":"J. Am. Vet. Med. Assoc."},{"key":"ref_7","doi-asserted-by":"crossref","unstructured":"Ragle, C.A. (2012). Evaluation of horses with signs of acute and chronic abdominal pain. Advances in Equine Laparoscopy, Wiley-Blackwell.","DOI":"10.1002\/9781118704875"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1111\/j.1532-950X.2005.00098.x","article-title":"Indications, surgical technique, and long-term experience with laparoscopic closure of the nephrosplenic space in standing horses","volume":"34","author":"Schubert","year":"2005","journal-title":"Vet. Surg."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"1361-3","DOI":"10.2460\/javma.1999.214.09.1361","article-title":"Ablation of the nephrosplenic space for treatment of recurring left dorsal displacement of the large colon in a racehorse","volume":"214","author":"Zekas","year":"1999","journal-title":"J. Am. Vet. Med. Assoc."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1111\/vsu.12434","article-title":"Prosthetic Mesh for Obliteration of the Nephrosplenic Space in Horses: 26 Clinical Cases","volume":"45","author":"Burke","year":"2016","journal-title":"Vet. Surg."},{"key":"ref_11","doi-asserted-by":"crossref","unstructured":"Blikslager, A.T., White, N., Moore, J.N., and Mair, T.S. (2017). Specific Diseases of the Ascending Colon. The Equine Acute Abdomen, John Wiley & Sons, Inc.. [3rd ed.]. Chapter 54.","DOI":"10.1002\/9781119063254"},{"key":"ref_12","doi-asserted-by":"crossref","unstructured":"Southwood, L.L. (2013). Colic Surgery. Practical Guide to Equine Colic, Wiley-Blackwell.","DOI":"10.1002\/9781118704783"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.jevs.2016.02.236","article-title":"Laparoscopic Uteropexy (Mesometrium Imbrication) in Three Mares Using a Barbed Suture","volume":"40","author":"Corsalini","year":"2016","journal-title":"J. Equine Vet. Sci."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1136\/vr.l6480","article-title":"How effective is surgical closure of the nephrosplenic space in preventing recurrent colic in horses?","volume":"185","author":"Gandini","year":"2019","journal-title":"Vet. Rec."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1111\/j.1532-950X.2012.01050.x","article-title":"Standing hand-assisted laparoscopic treatment of left dorsal displacement of the large colon and closure of the nephrosplenic space","volume":"42","author":"Bussy","year":"2013","journal-title":"Vet. Surg."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1111\/j.1532-950X.2006.00171.x","article-title":"Laparoscopic obliteration of the nephrosplenic space using polypropylene mesh in five horses","volume":"35","author":"Epstein","year":"2006","journal-title":"Vet. Surg."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1007\/s00268-006-0317-9","article-title":"Intraperitoneal polypropylene mesh hernia repair complicates subsequent abdominal surgery","volume":"31","author":"Halm","year":"2007","journal-title":"World J. Surg."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/S0022-4804(03)00158-6","article-title":"Assessment of adhesion formation to intra-abdominal polypropylene mesh and polytetrafluoroethylene mesh","volume":"114","author":"Matthews","year":"2003","journal-title":"J. Surg. Res."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"2159","DOI":"10.1007\/s11695-017-2628-3","article-title":"The Use of Unidirectional Knotless Barbed Suture for Enterotomy Closure in Roux-en-Y Gastric Bypass: A Randomized Comparative Study","volume":"27","author":"Gys","year":"2017","journal-title":"Obes. Surg."},{"key":"ref_20","unstructured":"Fischer, A.T. (2002). Equine Diagnostic and Surgical Laparoscopy, W.B. Saunders Company."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1111\/j.1532-950X.2005.00099.x","article-title":"Laparoscopic closure of the nephrosplenic space for prevention of recurrent nephrosplenic entrapment of the ascending colon","volume":"34","author":"Farstvedt","year":"2005","journal-title":"Vet. 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