{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T20:54:44Z","timestamp":1792788884774,"version":"4.5.0"},"reference-count":42,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2021,5,13]],"date-time":"2021-05-13T00:00:00Z","timestamp":1620864000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100007652","name":"Instituto Nacional de Investigaci\u00f3n y Tecnolog\u00eda Agraria y Alimentaria","doi-asserted-by":"publisher","award":["RTA2017-00055-C02-02"],"award-info":[{"award-number":["RTA2017-00055-C02-02"]}],"id":[{"id":"10.13039\/100007652","id-type":"DOI","asserted-by":"publisher"}]},{"name":"PCTI 2018\u20132020 (GRUPIN)","award":["IDI2018-000237"],"award-info":[{"award-number":["IDI2018-000237"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animals"],"abstract":"<jats:p>This study aimed to investigate the seroprevalence of C. burnetii in domestic ruminants, wild ungulates, as well as the current situation of Q fever in humans in a small region in northwestern Spain where a close contact at the wildlife\u2013livestock\u2013human interface exists, and information on C. burnetii infection is scarce. Seroprevalence of C. burnetii was 8.4% in sheep, 18.4% in cattle, and 24.4% in goats. Real-time PCR analysis of environmental samples collected in 25 livestock farms detected Coxiella DNA in dust and\/or aerosols collected in 20 of them. Analysis of sera from 327 wild ungulates revealed lower seroprevalence than that found in domestic ruminants, with 8.4% of Iberian red deer, 7.3% chamois, 6.9% fallow deer, 5.5% European wild boar and 3.5% of roe deer harboring antibodies to C. burnetii. Exposure to the pathogen in humans was determined by IFAT analysis of 1312 blood samples collected from patients admitted at healthcare centers with Q fever compatible symptoms, such as fever and\/or pneumonia. Results showed that 15.9% of the patients had IFAT titers \u2265 1\/128 suggestive of probable acute infection. This study is an example of a One Health approach with medical and veterinary institutions involved in investigating zoonotic diseases.<\/jats:p>","DOI":"10.3390\/ani11051395","type":"journal-article","created":{"date-parts":[[2021,5,14]],"date-time":"2021-05-14T03:28:36Z","timestamp":1620962916000},"page":"1395","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":40,"title":["One Health Approach: An Overview of Q Fever in Livestock, Wildlife and Humans in Asturias (Northwestern Spain)"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6378-8833","authenticated-orcid":false,"given":"Alberto","family":"Esp\u00ed","sequence":"first","affiliation":[{"name":"Department of Animal Health, Regional Service for Agrofood Research and Development (SERIDA), 33394 Gij\u00f3n, Spain"},{"name":"Translational Microbiology Consolidated Group, Instituto de Investigaci\u00f3n Sanitaria del Principado de Asturias (Health Research Institute of Asturias, ISPA), Av. del Hospital Universitario, s\/n, 33011 Oviedo, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6574-4241","authenticated-orcid":false,"given":"Ana","family":"del Cerro","sequence":"additional","affiliation":[{"name":"Department of Animal Health, Regional Service for Agrofood Research and Development (SERIDA), 33394 Gij\u00f3n, Spain"},{"name":"Translational Microbiology Consolidated Group, Instituto de Investigaci\u00f3n Sanitaria del Principado de Asturias (Health Research Institute of Asturias, ISPA), Av. del Hospital Universitario, s\/n, 33011 Oviedo, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4080-3057","authenticated-orcid":false,"given":"\u00c1lvaro","family":"Oleaga","sequence":"additional","affiliation":[{"name":"Translational Microbiology Consolidated Group, Instituto de Investigaci\u00f3n Sanitaria del Principado de Asturias (Health Research Institute of Asturias, ISPA), Av. del Hospital Universitario, s\/n, 33011 Oviedo, Spain"},{"name":"SERPA\u2014Sociedad de Servicios del Principado de Asturias S.A., 33202 Gij\u00f3n, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mercedes","family":"Rodr\u00edguez-P\u00e9rez","sequence":"additional","affiliation":[{"name":"Translational Microbiology Consolidated Group, Instituto de Investigaci\u00f3n Sanitaria del Principado de Asturias (Health Research Institute of Asturias, ISPA), Av. del Hospital Universitario, s\/n, 33011 Oviedo, Spain"},{"name":"Department of Microbiology, Central Hospital of Asturias (HUCA), 33011 Oviedo, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9151-3180","authenticated-orcid":false,"given":"Ceferino M.","family":"L\u00f3pez","sequence":"additional","affiliation":[{"name":"Department of Animal Pathology, Animal Health, Veterinary Faculty, University of Santiago de Compostela, 27071 Lugo, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7089-9670","authenticated-orcid":false,"given":"Ana","family":"Hurtado","sequence":"additional","affiliation":[{"name":"Department of Animal Health, NEIKER-Basque Institute for Agricultural Research and Development, Basque Research and Technology Alliance (BRTA), 48160 Derio, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lu\u00eds D.","family":"Rodr\u00edguez-Mart\u00ednez","sequence":"additional","affiliation":[{"name":"Animal Health Laboratory (LSAPA), Government of Principado de Asturias, 33201 Gij\u00f3n, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jes\u00fas F.","family":"Barandika","sequence":"additional","affiliation":[{"name":"Department of Animal Health, NEIKER-Basque Institute for Agricultural Research and Development, Basque Research and Technology Alliance (BRTA), 48160 Derio, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7404-1380","authenticated-orcid":false,"given":"Ana L.","family":"Garc\u00eda-P\u00e9rez","sequence":"additional","affiliation":[{"name":"Department of Animal Health, NEIKER-Basque Institute for Agricultural Research and Development, Basque Research and Technology Alliance (BRTA), 48160 Derio, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,5,13]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1128\/CMR.00045-16","article-title":"From Q Fever to Coxiella burnetii Infection: A Paradigm Change","volume":"30","author":"Eldin","year":"2017","journal-title":"Clin. 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