{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T02:53:22Z","timestamp":1789095202652,"version":"build-2803163510"},"reference-count":70,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2021,5,20]],"date-time":"2021-05-20T00:00:00Z","timestamp":1621468800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animals"],"abstract":"<jats:p>Trypanorhyncha are cestodes commonly infecting marine fish. Numerous studies have detailed the biology of Trypanorhyncha species, but information on the pathological changes produced by these parasites is limited. Dusky groupers are keystone species necessary for the preservation of several marine ecosystems. Considering their vulnerable state of conservation and the efforts being made to culture them, identification of the effects caused by Trypanorhyncha is vital. Here, we aimed to determine the prevalence and pathological changes produced by Trypanorhyncha in dusky groupers from the Canary Islands. The prevalence of trypanorhynch plerocerci was 96%. Grossly, in the abdominal cavity, there were numerous larvae-filled cysts and nodules. These were embedded in abundant fibrosis, producing visceral adhesions. Histologically, affecting the peritoneum, stomach, and intestine there were numerous degenerated encysted plerocerci and extensive deposition of mature connective tissue. These findings indicate that Trypanorhyncha is highly prevalent in adult dusky groupers from the Canary Islands, producing a progressive and chronic response. Furthermore, fish immune system appears to attempt to eliminate the parasites through fibrous encapsulation. Nonetheless, extensive fibrosis may have a detrimental impact on fish health when adjacent cells or tissues are compressed and their functions impaired.<\/jats:p>","DOI":"10.3390\/ani11051471","type":"journal-article","created":{"date-parts":[[2021,5,20]],"date-time":"2021-05-20T11:45:57Z","timestamp":1621511157000},"page":"1471","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["A Study on the Pathological Effects of Trypanorhyncha Cestodes in Dusky Groupers Epinephelus marginatus from the Canary Islands"],"prefix":"10.3390","volume":"11","author":[{"given":"Carolina","family":"de Sales-Ribeiro","sequence":"first","affiliation":[{"name":"Veterinary Histology and Pathology, Institute for Animal Health and Food Safety (IUSA), Veterinary School, Universidad Las Palmas de Gran Canaria, 35413 Arucas, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miguel A.","family":"Rivero","sequence":"additional","affiliation":[{"name":"Veterinary Histology and Pathology, Institute for Animal Health and Food Safety (IUSA), Veterinary School, Universidad Las Palmas de Gran Canaria, 35413 Arucas, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5281-0521","authenticated-orcid":false,"given":"Antonio","family":"Fern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Veterinary Histology and Pathology, Institute for Animal Health and Food Safety (IUSA), Veterinary School, Universidad Las Palmas de Gran Canaria, 35413 Arucas, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5027-3072","authenticated-orcid":false,"given":"Natalia","family":"Garc\u00eda-\u00c1lvarez","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases and Ichthiopathology, Institute for Animal Health and Food Safety (IUSA), Veterinary School, Universidad Las Palmas de Gran Canaria, 35413 Arucas, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge Francisco","family":"Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Division of Animal Production and Biotechnology, Institute for Animal Health and Food Safety (IUSA), Veterinary School, Universidad Las Palmas de Gran Canaria, 35413 Arucas, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oscar","family":"Quesada-Canales","sequence":"additional","affiliation":[{"name":"Veterinary Histology and Pathology, Institute for Animal Health and Food Safety (IUSA), Veterinary School, Universidad Las Palmas de Gran Canaria, 35413 Arucas, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2575-0997","authenticated-orcid":false,"given":"Mar\u00eda Jos\u00e9","family":"Caballero","sequence":"additional","affiliation":[{"name":"Veterinary Histology and Pathology, Institute for Animal Health and Food Safety (IUSA), Veterinary School, Universidad Las Palmas de Gran Canaria, 35413 Arucas, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,5,20]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"93","DOI":"10.3354\/dao070093","article-title":"Macroparasites of five species of ray (genus Raja) on the northwest coast of Spain","volume":"70","author":"Alvarez","year":"2006","journal-title":"Dis. 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