{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T02:04:09Z","timestamp":1760234649097,"version":"build-2065373602"},"reference-count":38,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2021,6,4]],"date-time":"2021-06-04T00:00:00Z","timestamp":1622764800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100017637","name":"Uniwersytet Przyrodniczy we Wroclawiu","doi-asserted-by":"publisher","award":["The research is financed under the individual student research project \u201eM\u0142ode umys\u0142y \u2013 Young Minds Project\u201d from the subsidy increased for the period 2020\u20132025 in the amount of 2% of the subsidy referred to Art. 387 (3) of the Law of 20 July 2018 on Highe"],"award-info":[{"award-number":["The research is financed under the individual student research project \u201eM\u0142ode umys\u0142y \u2013 Young Minds Project\u201d from the subsidy increased for the period 2020\u20132025 in the amount of 2% of the subsidy referred to Art. 387 (3) of the Law of 20 July 2018 on Highe"]}],"id":[{"id":"10.13039\/501100017637","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animals"],"abstract":"<jats:p>The mitral valve apparatus is a complex structure consisting of the mitral ring, valve leaflets, papillary muscles and Chordae tendineae (CT). The latter are mainly responsible for the mechanical functions of the valve. Our study included investigations of the biomechanical and structural properties of CT collected from canine and porcine hearts, as there are no studies about these properties of canine CT. We performed a static uniaxial tensile test on CT samples and a histopathological analysis in order to examine their microstructure. The results were analyzed to clarify whether the changes in mechanical persistence of Chordae tendineae are combined with the alterations in their structure. This study offers clinical insight for future research, allowing for an understanding of the process of Chordae tendineae rupture that happens during degenerative mitral valve disease\u2014the most common heart disease in dogs.<\/jats:p>","DOI":"10.3390\/ani11061678","type":"journal-article","created":{"date-parts":[[2021,6,4]],"date-time":"2021-06-04T11:12:13Z","timestamp":1622805133000},"page":"1678","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Biomechanical\u2013Structural Correlation of Chordae tendineae in Animal Models: A Pilot Study"],"prefix":"10.3390","volume":"11","author":[{"given":"Justyn","family":"Gach","sequence":"first","affiliation":[{"name":"Department of Internal Medicine and Clinic of Diseases of Horses, Dogs and Cats, Faculty of Veterinary Medicine, Wroc\u0142aw University of Environmental and Life Sciences, Grunwaldzki sq. 47, 50-366 Wroc\u0142aw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5166-856X","authenticated-orcid":false,"given":"Izabela","family":"Janus","sequence":"additional","affiliation":[{"name":"Department of Pathology, Faculty of Veterinary Medicine, Wroc\u0142aw University of Environmental and Life Sciences, C. 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Norwida 31 Street, 50-376 Wroc\u0142aw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3956-8483","authenticated-orcid":false,"given":"Agnieszka","family":"Mackiewicz","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, University of Zielona G\u00f3ra, Prof. Z Szafrana 4 Street, 65-516 Zielona G\u00f3ra, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2699-3528","authenticated-orcid":false,"given":"Tomasz","family":"Klekiel","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, University of Zielona G\u00f3ra, Prof. Z Szafrana 4 Street, 65-516 Zielona G\u00f3ra, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7899-3936","authenticated-orcid":false,"given":"Agnieszka","family":"Noszczyk-Nowak","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine and Clinic of Diseases of Horses, Dogs and Cats, Faculty of Veterinary Medicine, Wroc\u0142aw University of Environmental and Life Sciences, Grunwaldzki sq. 47, 50-366 Wroc\u0142aw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,6,4]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4103\/1995-705X.152994","article-title":"Morphological study of chordae tendinae in human cadaveric hearts","volume":"16","author":"Gunnal","year":"2015","journal-title":"Heart Views Off. 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