{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T01:09:55Z","timestamp":1790644195018,"version":"4.1.0"},"reference-count":35,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2021,7,8]],"date-time":"2021-07-08T00:00:00Z","timestamp":1625702400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animals"],"abstract":"<jats:p>Ovine anaplasmosis is a vector-borne disease caused by Anaplasma ovis and mainly transmitted through tick bites. In Spain, the first outbreak of ovine anaplasmosis occurred in 2014. An epidemiological study in fifty-one farms was carried out associated with this outbreak in the affected geographical area. An epidemiological questionnaire was performed. In addition, whole blood samples were taken for molecular analysis in 47 of these farms to determine the prevalence of infection of Anaplasma ovis. A. ovis was present in 44 out of 47 PCR-analysed farms (93.6%). However, only 40.4% of the studied farms showed severe clinical signs. The clinical signs affected mainly young animals, which showed severe anaemia, weakness, anorexia, cachexia and epiphora. The early culling of young animals was more frequently reported by severely affected farms than the analysed farms without clinical signs (71.4% vs. 12.5%, p &lt; 0.001). The geographical area where the farm is located seems to be relevant for the presence of clinical signs of the disease. Ovine anaplasmosis is an emerging disease in Europe that spreads rapidly through tick bites and is capable of causing significant economic losses when it spreads in a naive area and causes an epidemic.<\/jats:p>","DOI":"10.3390\/ani11072036","type":"journal-article","created":{"date-parts":[[2021,7,8]],"date-time":"2021-07-08T04:32:49Z","timestamp":1625718769000},"page":"2036","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Epidemiological Study Related to the First Outbreak of Ovine Anaplasmosis in Spain"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7822-6646","authenticated-orcid":false,"given":"Delia","family":"Lacasta","sequence":"first","affiliation":[{"name":"Animal Pathology Department, Instituto Agroalimentario de Arag\u00f3n-IA2, Universidad de Zaragoza-CITA, 50013 Zaragoza, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miguel","family":"Lorenzo","sequence":"additional","affiliation":[{"name":"Animal Pathology Department, Instituto Agroalimentario de Arag\u00f3n-IA2, Universidad de Zaragoza-CITA, 50013 Zaragoza, Spain"},{"name":"Centro Cl\u00ednico Veterinario de Jaca, C\/Estudios 5, 22700 Jaca, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4655-9171","authenticated-orcid":false,"given":"Jos\u00e9 Mar\u00eda","family":"Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Animal Pathology Department, Instituto Agroalimentario de Arag\u00f3n-IA2, Universidad de Zaragoza-CITA, 50013 Zaragoza, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Ruiz de Arcaute","sequence":"additional","affiliation":[{"name":"Animal Pathology Department, Instituto Agroalimentario de Arag\u00f3n-IA2, Universidad de Zaragoza-CITA, 50013 Zaragoza, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2497-9028","authenticated-orcid":false,"given":"Alfredo \u00c1ngel","family":"Benito","sequence":"additional","affiliation":[{"name":"Exopol S.L., Pol. R\u00edo G\u00e1llego D-8, 50840 Zaragoza, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Baselga","sequence":"additional","affiliation":[{"name":"Exopol S.L., Pol. R\u00edo G\u00e1llego D-8, 50840 Zaragoza, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda Eugenia","family":"Milian","sequence":"additional","affiliation":[{"name":"A.D.S. Bajo Arag\u00f3n Matarra\u00f1a, 44596 Teruel, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nuria","family":"Lorenzo","sequence":"additional","affiliation":[{"name":"A.D.S. ovina y caprina del Matarra\u00f1a Turolense, 44596 Teruel, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Calasanz","family":"Jim\u00e9nez","sequence":"additional","affiliation":[{"name":"Gabinete T\u00e9cnico Veterinario S.L., C\/Isla conejera sn, 50013 Zaragoza, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6209-4282","authenticated-orcid":false,"given":"Sergio","family":"Villanueva-Saz","sequence":"additional","affiliation":[{"name":"Animal Pathology Department, Instituto Agroalimentario de Arag\u00f3n-IA2, Universidad de Zaragoza-CITA, 50013 Zaragoza, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis Miguel","family":"Ferrer","sequence":"additional","affiliation":[{"name":"Animal Pathology Department, Instituto Agroalimentario de Arag\u00f3n-IA2, Universidad de Zaragoza-CITA, 50013 Zaragoza, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,7,8]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1016\/j.vetmic.2007.01.024","article-title":"First serological and molecular evidence on the endemicity of Anaplasma ovis and A. marginale in Hungary","volume":"122","author":"Hornok","year":"2007","journal-title":"Vet. 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