{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T01:38:59Z","timestamp":1789781939652,"version":"4.0.1"},"reference-count":31,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2022,1,6]],"date-time":"2022-01-06T00:00:00Z","timestamp":1641427200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animals"],"abstract":"<jats:p>The lungworm Aelurostrongylus abstrusus is one of the main causes of respiratory diseases in cats worldwide. This report describes the unusual case of a kitten infected with A. abstrusus and presented to a veterinary clinic in Brazil with lethargy, dysphagia, non-ambulatory tetraplegia, and pelvic limbs bilateral myoclonus. The clinical picture of the kitten worsened with generalized flaccid tetraplegia and death a few days after hospitalization. At necropsy, hemorrhagic necrosis and subarachnoid hemorrhages were detected in several areas of the central nervous system. Nematode stages were found at post-mortem histological examinations in lungs, cerebellum, subarachnoid space of the brain and spinal cord. Microscopic and molecular (PCRs-coupled-sequencing protocols) examination showed the presence of A. abstrusus in histological samples. This study describes the first neurological aelurostrongylosis due to ectopic localization of adult worms in the central nervous system of a cat, causing acute hemorrhagic multifocal meningoencephalomyelitis. Further studies are necessary to elucidate whether unusual localizations and the migration of A. abstrusus are more frequent than expected.<\/jats:p>","DOI":"10.3390\/ani12020128","type":"journal-article","created":{"date-parts":[[2022,1,6]],"date-time":"2022-01-06T03:41:32Z","timestamp":1641440492000},"page":"128","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Hemorrhagic Meningoencephalomyelitis Due to Ectopic Localization of Aelurostrongylus abstrusus in a Cat: First Case Report"],"prefix":"10.3390","volume":"12","author":[{"given":"Fernanda Viola","family":"Tinoco","sequence":"first","affiliation":[{"name":"Clinica Veterin\u00e1ria C\u00e3es & Gatos, Barra do Pira\u00ed 27113-150, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6344-0239","authenticated-orcid":false,"given":"Simone","family":"Morelli","sequence":"additional","affiliation":[{"name":"Faculty of Veterinary Medicine, University of Teramo, 64100 Teramo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marilene","family":"de Farias Brito","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Public Health, Federal Rural University of Rio de Janeiro, Serop\u00e9dica 23897-000, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8851-680X","authenticated-orcid":false,"given":"Gabriela","family":"Oliveira Pereira","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Public Health, Federal Rural University of Rio de Janeiro, Serop\u00e9dica 23897-000, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariana","family":"Correia Oliveira","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Public Health, Federal Rural University of Rio de Janeiro, Serop\u00e9dica 23897-000, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8347-0769","authenticated-orcid":false,"given":"Anastasia","family":"Diakou","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences, School of Veterinary Medicine, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5177-3386","authenticated-orcid":false,"given":"Mariasole","family":"Colombo","sequence":"additional","affiliation":[{"name":"Faculty of Veterinary Medicine, University of Teramo, 64100 Teramo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3372-717X","authenticated-orcid":false,"given":"Antonio","family":"Frangipane di Regalbono","sequence":"additional","affiliation":[{"name":"Department of Animal Medicine, Production and Health, University of Padova, Legnaro, 35020 Padova, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donato","family":"Traversa","sequence":"additional","affiliation":[{"name":"Faculty of Veterinary Medicine, University of Teramo, 64100 Teramo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,1,6]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Morelli, S., Diakou, A., Colombo, M., Di Cesare, A., Barlaam, A., Dimzas, D., and Traversa, D. 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