{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T10:33:28Z","timestamp":1789641208663,"version":"4.0.0"},"reference-count":126,"publisher":"MDPI AG","issue":"23","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animals"],"abstract":"<jats:p>Bovine tuberculosis (bTB) is a disease of cattle that represents a risk to public health and causes severe economic losses to the livestock industry. Recently, one of the strategies recommended for reducing the prevalence of the disease in animals is the use of the BCG vaccine, alone or in combination with proteins. It has been shown that the vaccine elicits a strong immune response, downsizes the number of animals with visible lesions, and reduces the rate of infection as well as the bacillary count. This paper, based on scientific evidence, makes suggestions about some practical vaccination alternatives that can be used in infected herds to reduce bTB prevalence, considering BCG strains, vaccine doses, routes of application, and age of the animals. Our conclusion is that vaccination is a promising alternative to be included in current control programs in underdeveloped countries to reduce the disease burden.<\/jats:p>","DOI":"10.3390\/ani12233377","type":"journal-article","created":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T03:03:41Z","timestamp":1669863821000},"page":"3377","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Vaccination Strategies in a Potential Use of the Vaccine against Bovine Tuberculosis in Infected Herds"],"prefix":"10.3390","volume":"12","author":[{"given":"Feliciano","family":"Mili\u00e1n-Suazo","sequence":"first","affiliation":[{"name":"Facultad de Ciencias Naturales, Universidad Aut\u00f3noma de Quer\u00e9taro, Santiago de Quer\u00e9taro 76010, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Gonz\u00e1lez-Ruiz","sequence":"additional","affiliation":[{"name":"Facultad de Ciencias Naturales, Universidad Aut\u00f3noma de Quer\u00e9taro, Santiago de Quer\u00e9taro 76010, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yesenia Guadalupe","family":"Contreras-Magallanes","sequence":"additional","affiliation":[{"name":"Facultad de Ciencias Naturales, Universidad Aut\u00f3noma de Quer\u00e9taro, Santiago de Quer\u00e9taro 76010, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susana Luc\u00eda","family":"Sosa-Gallegos","sequence":"additional","affiliation":[{"name":"Facultad de Ciencias Naturales, Universidad Aut\u00f3noma de Quer\u00e9taro, Santiago de Quer\u00e9taro 76010, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabel","family":"B\u00e1rcenas-Reyes","sequence":"additional","affiliation":[{"name":"Facultad de Ciencias Naturales, Universidad Aut\u00f3noma de Quer\u00e9taro, Santiago de Quer\u00e9taro 76010, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7821-9916","authenticated-orcid":false,"given":"Germinal Jorg\u00e9","family":"Cant\u00f3-Alarc\u00f3n","sequence":"additional","affiliation":[{"name":"Facultad de Ciencias Naturales, Universidad Aut\u00f3noma de Quer\u00e9taro, Santiago de Quer\u00e9taro 76010, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elba","family":"Rodr\u00edguez-Hern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Centro Nacional de Investigaci\u00f3n Disciplinaria en Fisiolog\u00eda y Mejoramiento Animal, Instituto Nacional de Investigaciones Forestales, Agr\u00edcolas y Pecuarias, Ajuchitl\u00e1n 76280, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,12,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0034-5288(02)00145-5","article-title":"The transmission of Mycobacterium bovis infection to cattle","volume":"74","author":"Phillips","year":"2003","journal-title":"Res. 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