{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T18:10:45Z","timestamp":1775671845307,"version":"3.50.1"},"reference-count":33,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2023,2,9]],"date-time":"2023-02-09T00:00:00Z","timestamp":1675900800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Xichang University Doctoral Fund","award":["YBZ202005"],"award-info":[{"award-number":["YBZ202005"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animals"],"abstract":"<jats:p>The present study investigated the effects of methionine (Met) on growth, immune function, and antioxidant capacity in partridge shank broilers, which were treated with either an anticoccidial drug or a coccidia vaccine. Chickens were fed five graded levels of Met (0.33%, 0.39%, 0.45%, 0.51%, or 0.57%) for 21 days in combination with the drug or vaccine. The results revealed that an optimal level of Met supplementation (1) increased ADFI (average daily feed intake), ADG (average daily gain), and F\/G values (feed-to-gain ratio), indicating improved production; (2) increased OPG levels (oocysts per gram feces), intestinal lesion scores, bursa of Fabricius and thymus indexes, and sIgA content; (3) improved GSH-Px activities, and increased content levels of T-protein, albumin, and urea nitrogen. In addition, birds in the anticoccidial drug group had higher final weights, higher ADFI and ADG values, as well as lower F\/G values, compared with birds in the vaccine group, indicating that coccidia vaccine reduces the performance of broilers. In conclusion, we found that an optimal level of dietary Met improved the production of partridge shank broilers, and this result might be related to immune function and antioxidant capacity. Optimal levels of digestible Met in terms of production performance (ADG and F\/G) and immune function (sIgA in ileum mucosa) in partridge shank broilers (1\u201321 days) were found to be 0.418, 0.451, and 0.451 of diet, respectively, when birds were given anticoccidial drug treatment, with corresponding figures of 0.444, 0.455, and 0.452% when the coccidia vaccine was administered.<\/jats:p>","DOI":"10.3390\/ani13040613","type":"journal-article","created":{"date-parts":[[2023,2,10]],"date-time":"2023-02-10T04:48:03Z","timestamp":1676004483000},"page":"613","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Dietary Methionine Increased the Growth Performances and Immune Function of Partridge Shank Broilers after Challenged with Coccidia"],"prefix":"10.3390","volume":"13","author":[{"given":"Anqiang","family":"Lai","sequence":"first","affiliation":[{"name":"College of Animal Science, Xichang University, Xichang 615000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zehong","family":"Yuan","sequence":"additional","affiliation":[{"name":"Animal Nutrition Institute, Sichuan Agricultural University, Chengdu 611130, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhongcheng","family":"Wang","sequence":"additional","affiliation":[{"name":"College of Animal Science, Xichang University, Xichang 615000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Binlong","family":"Chen","sequence":"additional","affiliation":[{"name":"College of Animal Science, Xichang University, Xichang 615000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Zhi","sequence":"additional","affiliation":[{"name":"College of Animal Science, Xichang University, Xichang 615000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhiqiu","family":"Huang","sequence":"additional","affiliation":[{"name":"College of Animal Science, Xichang University, Xichang 615000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi","family":"Zhang","sequence":"additional","affiliation":[{"name":"College of Animal Science, Xichang University, Xichang 615000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,2,9]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1707","DOI":"10.3382\/ps\/pew432","article-title":"Effects of dietary methionine on growth performance, meat quality and oxidative status of breast muscle in fast- and slow-growing broilers","volume":"96","author":"Wen","year":"2017","journal-title":"Poult"},{"key":"ref_2","unstructured":"Rano, N.B. 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