{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T15:16:48Z","timestamp":1768835808009,"version":"3.49.0"},"reference-count":66,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2023,4,18]],"date-time":"2023-04-18T00:00:00Z","timestamp":1681776000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animals"],"abstract":"<jats:p>Lavender administration in humans has been shown to promote calmness without the side effects often observed with benzodiazepines. Studies in both humans and rodents have found that ingestion of oral lavender capsules resulted in significantly decreased anxiety. Additionally, mice developed an anti-conflict effect and humans increased socially inclusive behaviors. Given the safety of oral lavender oil and the observed benefits, we administered daily lavender capsules to six chimpanzees who exhibited conflict-instigating behaviors in an effort to further decrease our already low levels of wounding. We compared the total number of wounds in 25 chimpanzees housed with the six lavender-treated chimpanzees in five different social groups (1) prior to administration of daily oral lavender capsules to (2) total wounds during daily oral lavender capsule treatment. We hypothesized that lavender therapy treatment would reduce overall wounding in the social groups. Surprisingly, overall wounding was higher during the lavender treatment period (p = 0.01), yet the percentage of wounds requiring treatment significantly decreased during the lavender therapy period (36% vs. 21%, p = 0.02).<\/jats:p>","DOI":"10.3390\/ani13081382","type":"journal-article","created":{"date-parts":[[2023,4,18]],"date-time":"2023-04-18T01:36:45Z","timestamp":1681781805000},"page":"1382","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["The Effects of Oral Lavender Therapy on Wounding in Chimpanzees (Pan troglodytes)"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1312-2694","authenticated-orcid":false,"given":"Elizabeth R.","family":"Magden","sequence":"first","affiliation":[{"name":"Michale E. Keeling Center for Comparative Medicine and Research, The University of Texas MD Anderson Cancer Center, 650 Cool Water Dr., Bastrop, TX 78602, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9393-3528","authenticated-orcid":false,"given":"Sarah","family":"Neal Webb","sequence":"additional","affiliation":[{"name":"Michale E. Keeling Center for Comparative Medicine and Research, The University of Texas MD Anderson Cancer Center, 650 Cool Water Dr., Bastrop, TX 78602, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9201-321X","authenticated-orcid":false,"given":"Susan P.","family":"Lambeth","sequence":"additional","affiliation":[{"name":"Michale E. Keeling Center for Comparative Medicine and Research, The University of Texas MD Anderson Cancer Center, 650 Cool Water Dr., Bastrop, TX 78602, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephanie J.","family":"Buchl","sequence":"additional","affiliation":[{"name":"Michale E. Keeling Center for Comparative Medicine and Research, The University of Texas MD Anderson Cancer Center, 650 Cool Water Dr., Bastrop, TX 78602, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven J.","family":"Schapiro","sequence":"additional","affiliation":[{"name":"Michale E. Keeling Center for Comparative Medicine and Research, The University of Texas MD Anderson Cancer Center, 650 Cool Water Dr., Bastrop, TX 78602, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,4,18]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"280","DOI":"10.3389\/fphar.2017.00280","article-title":"Exploring pharmacological mechanisms of lavender (Lavandula angustifolia) essential oil on central nervous system targets","volume":"8","author":"Lopez","year":"2017","journal-title":"Front. Pharmacol."},{"key":"ref_2","first-page":"56","article-title":"Composition, biological properties, and therapeutic effects of lavender (Lavandula angustifolia). A review","volume":"60","author":"Prusinowska","year":"2014","journal-title":"Kerba Pol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"102832","DOI":"10.1016\/j.ctim.2022.102832","article-title":"The effect of lavender on stress in individuals: A systematic review and meta-analysis","volume":"68","author":"Ghavami","year":"2022","journal-title":"Complement. Ther. Med."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1007\/s00210-023-02392-x","article-title":"A review of the bioactive components and pharmacological properties of Lavandula species","volume":"396","author":"Batiha","year":"2023","journal-title":"Naunyn-Schmiedeberg\u2019s Arch. Pharm."},{"key":"ref_5","first-page":"1163","article-title":"Medicinal uses of lavender oil (Lavandula latifolia) and its effect on human health","volume":"19","author":"Bagrl","year":"2019","journal-title":"Plant Arch."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1071\/HI05035","article-title":"Lavender essential oil: A review","volume":"10","author":"Cavanagh","year":"2005","journal-title":"Aust. Infect. Control."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1080\/10412905.2006.9699184","article-title":"Comparative chemical composition of steam-distilled and water-soluble essential oils of South American marigold (Tagetes minuta L.)","volume":"18","author":"Rajeswara","year":"2006","journal-title":"J. Essent. Oil Res."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"e202200536","DOI":"10.1002\/cbdv.202200536","article-title":"Annual Phytochemical variations and antioxidant activity within the aerial parts of Lavandula angustifolia, an evergreen medicinal plant","volume":"19","author":"Najafian","year":"2022","journal-title":"Chem. Biodivers."},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"Kwiatkowski, P., \u0141opusiewicz, \u0141., Kostek, M., Droz\u0142owska, E., Pruss, A., Wojciuk, B., Sienkiewicz, M., Zieli\u0144ska-Bli\u017aniewska, H., and Do\u0142\u0119gowska, B. (2019). The Antibacterial Activity of Lavender Essential Oil Alone and In Combination with Octenidine Dihydrochloride against MRSA Strains. Molecules, 25.","DOI":"10.3390\/molecules25010095"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1099\/jmm.0.027748-0","article-title":"Chemical composition and antifungal activity of the essential oils of Lavandula viridis L\u2019Her","volume":"60","author":"Zuzarte","year":"2011","journal-title":"J. Med. Microbiol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1046\/j.1365-2648.1995.21010034.x","article-title":"Sensing an improvement: An experimental study to evaluate the use of aromatherapy, massage and periods of rest in an intensive care unit","volume":"21","author":"Dunn","year":"1995","journal-title":"J. Adv. Nurs."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1111\/j.1600-0528.2009.00511.x","article-title":"The effects of lavender scent on dental patient anxiety levels: A cluster randomized-controlled trial","volume":"38","author":"Kritsidima","year":"2010","journal-title":"Community Dent. Oral Epidemiol."},{"key":"ref_13","first-page":"377","article-title":"The effect of odors on human newborn infants under stress","volume":"19","author":"Kawakami","year":"1997","journal-title":"Infant Behav. Develop."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.physbeh.2005.06.031","article-title":"Ambient odors of orange and lavender reduce anxiety and improve mood in a dental office","volume":"86","author":"Lehrner","year":"2005","journal-title":"Physiol. Behav."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1002\/gps.593","article-title":"Lavender oil as a treatment for agitated behaviour in severe dementia: A placebo-controlled study","volume":"17","author":"Holmes","year":"2002","journal-title":"Int. J. Geriatr. Psychiatr."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"5469","DOI":"10.3390\/s110505469","article-title":"Cognitive facilitation following intentional odor exposure","volume":"11","author":"Johnson","year":"2011","journal-title":"Sensors"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"153099","DOI":"10.1016\/j.phymed.2019.153099","article-title":"Effects of lavender on anxiety: A systematic review and meta-analysis","volume":"65","author":"Donelli","year":"2019","journal-title":"Phytomedicine"},{"key":"ref_18","unstructured":"(2022, November 09). National Institute of Mental Health, Available online: https:\/\/www.nimh.nih.gov\/health\/statistics\/any-anxiety-disorder#:~:text=An%20estimated%2031.1%25%20of%20U.S.,some%20time%20in%20their%20lives."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"147","DOI":"10.9740\/mhc.2017.07.147","article-title":"Essential oil of lavender in anxiety disorders: Ready for prime time?","volume":"7","author":"Malcolm","year":"2017","journal-title":"Ment. Health Clinician"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"69","DOI":"10.3233\/THC-2007-15201","article-title":"Autonomic nervous function and localization of cerebral activity during lavender aromatic immersion","volume":"15","author":"Duan","year":"2007","journal-title":"Technol. Health Care"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.psychres.2005.12.012","article-title":"Smelling lavender and rosemary increases free radical scavenging activity and decreases cortisol level in saliva","volume":"150","author":"Atsumi","year":"2007","journal-title":"Psychiatry Res."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"964","DOI":"10.1016\/j.archoralbio.2008.04.002","article-title":"Effect of lavender aroma on salivary endocrinological stress markers","volume":"53","author":"Toda","year":"2008","journal-title":"Arch. Oral Biol."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1097\/YIC.0b013e32833b3242","article-title":"Silexan, an orally administered Lavandula oil preparation, is effective in the treatment of \u2018subsyndromal\u2019 anxiety disorder: A randomized, double-blind, placebo-controlled trial","volume":"25","author":"Kasper","year":"2010","journal-title":"Int. Clin. Psychopharmacol."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.phymed.2009.10.006","article-title":"A multi-center, double-blind, randomized study of the lavender oil preparation Silexan in comparison to Lorazepam for generalized anxiety disorder","volume":"17","author":"Woelk","year":"2010","journal-title":"Phytomedicine"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1017\/S1461145714000017","article-title":"Lavender oil preparation Silexan if effective in generalized anxiety disorder\u2014A randomized, double-blind comparison to placebo and paroxetine","volume":"17","author":"Kasper","year":"2014","journal-title":"Int. J. Neuropsychopharmacol."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"1960","DOI":"10.1016\/j.euroneuro.2015.07.024","article-title":"Efficacy of orally administered Silexan in patients with anxiety-related restlessness and disturbed sleep\u2014A randomized, placebo-controlled trial","volume":"25","author":"Kasper","year":"2015","journal-title":"Eur. Neuropsychopharmacol."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/j.euroneuro.2015.12.002","article-title":"Efficacy of Silexan in mixed anxiety-depression\u2014A randomized, placebo-controlled trial","volume":"26","author":"Kasper","year":"2016","journal-title":"Eur. Neuropsychopharmacol."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/j.phymed.2012.02.002","article-title":"Effects of lavender oil inhalation on improving scopolamine-induced spatioal memory impairment in laboratory rats","volume":"19","author":"Hritcu","year":"2012","journal-title":"Phytomedicine"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1016\/j.pbb.2006.10.026","article-title":"Anticonflict effects of lavender oil and identification of its active constituents","volume":"85","author":"Umezu","year":"2006","journal-title":"Pharmacol. Biochem. Behav."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/j.phymed.2009.10.002","article-title":"Effects of inhaled Linalool in anxiety, social interaction, and aggressive behavior in mice","volume":"17","author":"Linck","year":"2010","journal-title":"Phytomedicine"},{"key":"ref_31","first-page":"681304","article-title":"Lavender and the Nervous System","volume":"2013","author":"Koulivand","year":"2013","journal-title":"eCAM"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/S0021-5198(19)30610-9","article-title":"Behavioral effects of plant-derived essential oils in the Geller type conflict test in mice","volume":"83","author":"Umezu","year":"2000","journal-title":"Jpn. J. Pharmacol."},{"key":"ref_33","first-page":"1486","article-title":"A question of scent: Lavender aroma promotes interpersonal trust","volume":"5","author":"Sellaro","year":"2014","journal-title":"Front. Psychol."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1093\/chemse\/bji061","article-title":"Effectiveness of aroma on work efficiency: Lavender aroma during recesses prevents deterioration of work performances","volume":"30","author":"Sakamoto","year":"2005","journal-title":"Chem. Senses"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1093\/chemse\/14.4.525","article-title":"Effects of ambient odors of lavender and cloves on cognition, memory, affect, and mood","volume":"14","author":"Ludvigson","year":"1989","journal-title":"Chem. Senses"},{"key":"ref_36","unstructured":"(2022, November 29). USDA Code of Federal Regulations, Title 21: 21CFR182.20, Available online: https:\/\/www.accessdata.fda.gov\/scripts\/cdrh\/cfdocs\/cfcfr\/cfrsearch.cfm?fr=182.20."},{"key":"ref_37","doi-asserted-by":"crossref","unstructured":"Reamer, L., Haller, R., Lambeth, S.P., and Schapiro, S.J. (2017). Handbook of Primate Behavioral Management, CRC Press.","DOI":"10.1201\/9781315120652-23"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1002\/(SICI)1098-2361(1997)16:4<327::AID-ZOO4>3.0.CO;2-C","article-title":"Effects of human activity on chimpanzee wounding","volume":"16","author":"Lambeth","year":"1997","journal-title":"Zoo Biol."},{"key":"ref_39","unstructured":"Institute for Laboratory Animal Research (2011). Guide for the Care and Use of Laboratory Animals, National Academies Press. [8th ed.]."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"e22749","DOI":"10.1002\/ajp.22749","article-title":"Captive chimpanzee (Pan troglodytes) behavior as a function of space per animal and enclosure type","volume":"80","author":"Hau","year":"2018","journal-title":"Am. J. Primatol."},{"key":"ref_41","first-page":"42","article-title":"Does group size matter? Captive chimpanzee (Pan troglodytes) behavior as a function of group size and composition","volume":"81","author":"Hau","year":"2019","journal-title":"Am. J. Primatol."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"18042","DOI":"10.1038\/s41598-019-54529-9","article-title":"Efficacy and safety of lavender essential oil (Silexan) capsules among patients suffering from anxiety disorders: A network meta-analysis","volume":"9","author":"Yap","year":"2019","journal-title":"Sci. Rep."},{"key":"ref_43","first-page":"e9457","article-title":"The Effects of Inhalation of Aromatherapy with Lavender on Anxiety Amongst Patients Undergoing Colonoscopy","volume":"13","author":"Mogharab","year":"2016","journal-title":"Mod. Care J."},{"key":"ref_44","first-page":"1159","article-title":"Phase I clinical trial of perillyl alcohol administered daily","volume":"4","author":"Ripple","year":"1998","journal-title":"Clin. Cancer Res."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1111\/j.1472-765X.2008.02406.x","article-title":"Comparison of bacteriostatic and bactericidal activity of 13 essential oils against strains with varying sensitivity to antibiotics","volume":"47","author":"Mayaud","year":"2008","journal-title":"Lett. Appl. Microbiol."},{"key":"ref_46","first-page":"475","article-title":"Acupuncture as an adjunct therapy for osteoarthritis in chimpanzees (Pan troglodytes)","volume":"52","author":"Magden","year":"2013","journal-title":"JAALAS"},{"key":"ref_47","first-page":"52","article-title":"Use of an implantable loop recorder in a chimpanzee (Pan troglodytes) to monitor cardiac arrhythmias and assess the effects of acupuncture and laser therapy","volume":"66","author":"Magden","year":"2016","journal-title":"Comp. Med."},{"key":"ref_48","unstructured":"Magden, E.R. (2017). Handbook of Primate Behavioral Management, CRC Press."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1002\/zoo.20388","article-title":"Case study: Training a chimpanzee (Pan troglodytes) to use a nebulizer to aid the treatment of airsacculitis","volume":"30","author":"Gresswell","year":"2011","journal-title":"Zoo Biol."},{"key":"ref_50","doi-asserted-by":"crossref","unstructured":"Kutlu, A.D., Cecen, D., Gurgen, S.G., Sayin, O., and Cetin, F. (2013). A comparison study of growth factor expression following treatment with transcutaneous electrical nerve stimulation, saline solution, povidone-iodine, and lavender oil in wounds healing. Evid. Based Complement. Altern. Med., 1\u20139.","DOI":"10.1155\/2013\/361832"},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"102679","DOI":"10.1016\/j.ctim.2021.102679","article-title":"The antidepressant effects of lavender (Lavandula angustifolia Mill.): A systematic review and meta-analysis of randomized controlled clinical trials","volume":"59","author":"Firoozeei","year":"2021","journal-title":"Complement. Ther. Med."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"438435","DOI":"10.1155\/2020\/4384350","article-title":"The effect of lavender (Lavandula stoechas L.) on reducing labor pain: A systematic review and meta-analysis","volume":"2020","author":"Kazeminia","year":"2020","journal-title":"Evid.-Based Complement. Altern. Med."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"29","DOI":"10.21859\/joqcr.3.1.29","article-title":"An update on the effect of massage and inhalation aromatherapy with lavender on labor pain relief: A systematic review and meta-analysis","volume":"3","author":"Mirzaiinajmabadi","year":"2018","journal-title":"J. Obstet. Gynecol. Cancer Res. (JOGCR)"},{"key":"ref_54","first-page":"1","article-title":"A review of randomized clinical trials on the effect of aromatherapy with lavender on labor pain relief","volume":"1","author":"Makvandi","year":"2016","journal-title":"Nurse Care Open Access J."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"385","DOI":"10.5005\/jp-journals-10005-2378","article-title":"The Effects of Lavender Essential Oil and its Clinical Implications in Dentistry: A Review","volume":"15","author":"Kajjari","year":"2022","journal-title":"Int. J. Clin. Pediatr. Dent."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"2294","DOI":"10.1016\/S0021-9258(18)34920-2","article-title":"The mechanism of cyclic monoterpene inhibition of hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase in vivo in the rat","volume":"257","author":"Clegg","year":"1982","journal-title":"J. Biol. Chem."},{"key":"ref_57","first-page":"52","article-title":"Effect of essential oils on the course of experimental atherosclerosis","volume":"5","author":"Kononova","year":"1990","journal-title":"Patol. Fiziol. I Eksperimental\u2019naia Ter."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1186\/1476-511X-12-189","article-title":"Lavender (Lavandula stoechas L.) essential oils attenuate hyperglycemia and protect against oxidative stress in alloxan-induced diabetic rats","volume":"12","author":"Sebai","year":"2013","journal-title":"Lipids Health Dis."},{"key":"ref_59","first-page":"979","article-title":"Induction of apoptosis in liver tumors by the monoterpene perillyl alcohol","volume":"55","author":"Mills","year":"1995","journal-title":"Cancer Res."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1007\/BF00685658","article-title":"Mammary carcinoma regression induced by perillyl alcohol, a hydroxylated analog of limonene","volume":"34","author":"Haag","year":"1994","journal-title":"Cancer Chemother. Pharmacol."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1002\/ptr.6827","article-title":"Lavender and coriander essential oils and their main component linalool exert a protective effect against amyloid-\u03b2 neurotoxicity","volume":"35","author":"Caputo","year":"2021","journal-title":"Phytother. Res."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1006\/phrs.2000.0671","article-title":"Linalool modifies the nicotinic receptor\u2013ion channel kinetics at the mouse neuromuscular junction","volume":"42","author":"Re","year":"2000","journal-title":"Pharmacol. Res."},{"key":"ref_63","unstructured":"Nordquist, J., and Wilson, D.R. (2023, February 08). What are the health benefits and risk of lavender?. Available online: https:\/\/www.medicalnewstoday.com\/articles\/265922."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"1579","DOI":"10.1016\/j.ijporl.2013.07.014","article-title":"Evaluation of the effect of aromatherapy with lavender essential oil on post-tonsillectomy pain in pediatric patients: A randomized controlled trial","volume":"77","author":"Soltani","year":"2013","journal-title":"Int. J. Pediatr. Otorhinolaryngol."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/j.ctim.2015.03.001","article-title":"The effect of topical application of lavender essential oil on the intensity of pain caused by the insertion of dialysis needles in hemodialysis patients: A randomized clinical trial","volume":"23","author":"Ghods","year":"2015","journal-title":"Complement. Ther. Med."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1590\/0001-3765201520150056","article-title":"Antioxidant, analgesic and anti-inflammatory effects of lavender essential oil","volume":"897","author":"Silva","year":"2015","journal-title":"An. Acad. Bras. Cienc."}],"container-title":["Animals"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2076-2615\/13\/8\/1382\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T19:17:50Z","timestamp":1760123870000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2076-2615\/13\/8\/1382"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,18]]},"references-count":66,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2023,4]]}},"alternative-id":["ani13081382"],"URL":"https:\/\/doi.org\/10.3390\/ani13081382","relation":{},"ISSN":["2076-2615"],"issn-type":[{"value":"2076-2615","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,4,18]]}}}