{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T19:57:15Z","timestamp":1789329435158,"version":"build-2803163510"},"reference-count":62,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2023,4,27]],"date-time":"2023-04-27T00:00:00Z","timestamp":1682553600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001807","name":"FAPESP (S\u00e3o Paulo Research Foundation)","doi-asserted-by":"publisher","award":["21\/10924-1"],"award-info":[{"award-number":["21\/10924-1"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"FAPESP (S\u00e3o Paulo Research Foundation)","doi-asserted-by":"publisher","award":["316447\/2021-8"],"award-info":[{"award-number":["316447\/2021-8"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"FAPESP (S\u00e3o Paulo Research Foundation)","doi-asserted-by":"publisher","award":["001"],"award-info":[{"award-number":["001"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"name":"CNPq (National Council for Scientific and Technological Development)","award":["21\/10924-1"],"award-info":[{"award-number":["21\/10924-1"]}]},{"name":"CNPq (National Council for Scientific and Technological Development)","award":["316447\/2021-8"],"award-info":[{"award-number":["316447\/2021-8"]}]},{"name":"CNPq (National Council for Scientific and Technological Development)","award":["001"],"award-info":[{"award-number":["001"]}]},{"name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","award":["21\/10924-1"],"award-info":[{"award-number":["21\/10924-1"]}]},{"name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","award":["316447\/2021-8"],"award-info":[{"award-number":["316447\/2021-8"]}]},{"name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","award":["001"],"award-info":[{"award-number":["001"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animals"],"abstract":"<jats:p>Porcine Respiratory Diseases Complex (PRDC) is a multifactorial disease that involves several bacterial pathogens, including Mycoplasma hyopneumoniae (M. hyopneumoniae), Actinobacillus pleuropneumoniae (A. pleuropneumoniae), Pasteurella multocida (P. multocida), Glaesserella parasuis (G. parasuis), and Streptococcus suis (S. suis). In pigs, the infection may cause lesions such pleurisy, which can lead to carcass condemnation. Hence, 1015 carcasses were selected from three different commercial pig farms, where the respiratory conditions were evaluated using slaughterhouse pleurisy evaluation system (SPES) and classified into five groups. In total, 106 pleural and lung fragments were collected for qPCR testing to identify the five abovementioned pathogens. A moderate correlation between the severity of the lesions and the presence of P. multocida (R = 0.38) and A. pleuropneumoniae (R = 0.28) was observed. Concerning the lung samples, the severity of the lesions was moderately correlated with the presence of P. multocida (R = 0.43) and M. hyopneumoniae (R = 0.35). Moreover, there was a strong correlation between the presence of P. multocida and M.hyopneumoniae in the pleura (R = 0.82). Finally, this approach may be a useful tool to identify and quantify causative agents of PRDC using qPCR, providing a comprehensive evaluation of its relevance, strength, and potential application in the field as a surveillance tool for veterinarians.<\/jats:p>","DOI":"10.3390\/ani13091493","type":"journal-article","created":{"date-parts":[[2023,4,28]],"date-time":"2023-04-28T01:33:40Z","timestamp":1682645620000},"page":"1493","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Associations between Pleurisy and the Main Bacterial Pathogens of the Porcine Respiratory Diseases Complex (PRDC)"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1140-7749","authenticated-orcid":false,"given":"Fernando Ant\u00f4nio Moreira","family":"Petri","sequence":"first","affiliation":[{"name":"School of Agricultural and Veterinarian Sciences, S\u00e3o Paulo State University (Unesp), Jaboticabal 14884-900, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geovana Coelho","family":"Ferreira","sequence":"additional","affiliation":[{"name":"School of Agricultural and Veterinarian Sciences, S\u00e3o Paulo State University (Unesp), Jaboticabal 14884-900, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"La\u00edza Pinto","family":"Arruda","sequence":"additional","affiliation":[{"name":"School of Agricultural and Veterinarian Sciences, S\u00e3o Paulo State University (Unesp), Jaboticabal 14884-900, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clarisse Sena","family":"Malcher","sequence":"additional","affiliation":[{"name":"School of Agricultural and Veterinarian Sciences, S\u00e3o Paulo State University (Unesp), Jaboticabal 14884-900, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriel Yuri","family":"Storino","sequence":"additional","affiliation":[{"name":"School of Agricultural and Veterinarian Sciences, S\u00e3o Paulo State University (Unesp), Jaboticabal 14884-900, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henrique Meiroz de Souza","family":"Almeida","sequence":"additional","affiliation":[{"name":"School of Agricultural and Veterinarian Sciences, S\u00e3o Paulo State University (Unesp), Jaboticabal 14884-900, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karina","family":"Sonalio","sequence":"additional","affiliation":[{"name":"School of Agricultural and Veterinarian Sciences, S\u00e3o Paulo State University (Unesp), Jaboticabal 14884-900, SP, Brazil"},{"name":"Unit of Porcine Health Management, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela Gomes da","family":"Silva","sequence":"additional","affiliation":[{"name":"School of Agricultural and Veterinarian Sciences, S\u00e3o Paulo State University (Unesp), Jaboticabal 14884-900, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1861-5076","authenticated-orcid":false,"given":"Lu\u00eds Guilherme de","family":"Oliveira","sequence":"additional","affiliation":[{"name":"School of Agricultural and Veterinarian Sciences, S\u00e3o Paulo State University (Unesp), Jaboticabal 14884-900, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,4,27]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1017\/S1466252311000120","article-title":"Polymicrobial respiratory disease in pigs","volume":"12","author":"Opriessnig","year":"2011","journal-title":"Anim. 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