{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T17:05:43Z","timestamp":1782925543922,"version":"3.54.5"},"reference-count":36,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T00:00:00Z","timestamp":1684368000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animals"],"abstract":"<jats:p>An individual\u2019s facial appearance is heavily influenced by facial symmetry. In the asymmetric mandible, periosteal apposition and endochondral ossification in one of the condyles may stimulate asymmetric growth of the body. Our aim was to review the impact on the growth following masseter resection. Relevant studies up to October 2022 were retrieved from PubMed, Scopus, and Web of Science. The PICOS method was utilized to determine eligibility, and the SYRCLE risk of bias tool was utilized to provide an estimate of potential bias. A predetermined algorithm was used to search the databases. The results of our systematic review of seven studies indicate that the masseter muscle strongly impacts craniofacial growth and development. Resection of the masseter muscle significantly reduces the sagittal and vertical development of the jaw in rats. In addition, the masseter muscle excision influences the mandibular morphology, including the condylar area, angle, and development direction of the jaw.<\/jats:p>","DOI":"10.3390\/ani13101680","type":"journal-article","created":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T06:32:58Z","timestamp":1684391578000},"page":"1680","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Effects on Facial Growth Following Masseter Muscle Resection in Growing Rats\u2014A Systematic Review"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3322-9974","authenticated-orcid":false,"given":"Georgia","family":"Kotantoula","sequence":"first","affiliation":[{"name":"Department of Orthodontics, School of Dentistry, National and Kapodistrian University of Athens, 11527 Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5435-4889","authenticated-orcid":false,"given":"Ioannis A.","family":"Tsolakis","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, School of Dentistry, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece"},{"name":"Department of Orthodontics, Case Western Reserve University, Cleveland, OH 44106, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5897-6116","authenticated-orcid":false,"given":"Ioannis","family":"Lyros","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, School of Dentistry, National and Kapodistrian University of Athens, 11527 Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2855-8623","authenticated-orcid":false,"given":"Miltiadis A.","family":"Makrygiannakis","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, School of Dentistry, National and Kapodistrian University of Athens, 11527 Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-3501-4247","authenticated-orcid":false,"given":"Christina","family":"Kanareli","sequence":"additional","affiliation":[{"name":"Private Practice, 75015 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Dalampira","sequence":"additional","affiliation":[{"name":"Private Practice, 54124 Thessaloniki, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3019-5438","authenticated-orcid":false,"given":"Apostolos I.","family":"Tsolakis","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, School of Dentistry, National and Kapodistrian University of Athens, 11527 Athens, Greece"},{"name":"Department of Orthodontics, Case Western Reserve University, Cleveland, OH 44106, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,5,18]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"196","DOI":"10.3109\/00016359509005972","article-title":"Masticatory muscle influence on craniofacial growth","volume":"53","author":"Kiliaridis","year":"1995","journal-title":"Acta Odontol. 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