{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:30:52Z","timestamp":1787027452942,"version":"build-2736575974"},"reference-count":33,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2023,6,9]],"date-time":"2023-06-09T00:00:00Z","timestamp":1686268800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animals"],"abstract":"<jats:p>The detection of subtle changes in the pituitary dimensions has relevant clinical implications. In cats, a few studies have established the cut-off values of the pituitary gland\u2019s dimensions using small and inhomogeneous samples. The aims of this study were: to determine by computed tomography (CT) the pituitary linear dimensions and the pituitary-to-brain (P:B) ratio in a sample of domestic short-haired (DSH) cats; to assess the effects of sex, age, and weight on pituitary dimensions; and to evaluate the inter- and intra-observer agreement for such measurements. All skull CTs of DSH cats performed over four years using a multidetector CT and a standardized protocol were retrospectively reviewed. The exclusion criteria were: clinical, laboratory, or CT alterations of the pituitary gland, brain diseases, fractures of the neurocranium, and diabetes. The pituitary dimensions and brain area were assessed by two different observers using multiplanar reconstructions and automated segmentation tools. Fifty-one cats were included in the final sample. The intraclass correlation coefficients for intra- and inter-observer reliability were good\/excellent, and moderate\/good, respectively. No differences between sexes were detected, and negligible correlations were found between age and weight. According to this study, a pituitary gland with a height &gt; 4 mm or a P:B ratio &gt; 0.49 mm should be considered enlarged.<\/jats:p>","DOI":"10.3390\/ani13121935","type":"journal-article","created":{"date-parts":[[2023,6,9]],"date-time":"2023-06-09T08:37:33Z","timestamp":1686299853000},"page":"1935","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Computed Tomographic Assessment of Pituitary Gland Dimensions in Domestic Short-Haired Cats"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7310-0246","authenticated-orcid":false,"given":"Dario","family":"Costanza","sequence":"first","affiliation":[{"name":"Interdepartmental Center of Veterinary Radiology, University of Napoli \u201cFederico II\u201d, Via Federico Delpino 1, 80137 Napoli, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3244-4135","authenticated-orcid":false,"given":"Pierpaolo","family":"Coluccia","sequence":"additional","affiliation":[{"name":"Interdepartmental Center of Veterinary Radiology, University of Napoli \u201cFederico II\u201d, Via Federico Delpino 1, 80137 Napoli, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1624-4240","authenticated-orcid":false,"given":"Luigi","family":"Auletta","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine and Animal Sciences (DIVAS), University of Milano, Via dell\u2019Universit\u00e0 6, 26900 Lodi, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1941-9138","authenticated-orcid":false,"given":"Erica","family":"Castiello","sequence":"additional","affiliation":[{"name":"Interdepartmental Center of Veterinary Radiology, University of Napoli \u201cFederico II\u201d, Via Federico Delpino 1, 80137 Napoli, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1851-5016","authenticated-orcid":false,"given":"Luigi","family":"Navas","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine and Animal Production, University of Napoli \u201cFederico II\u201d, Via Federico Delpino 1, 80137 Napoli, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6841-1963","authenticated-orcid":false,"given":"Adelaide","family":"Greco","sequence":"additional","affiliation":[{"name":"Interdepartmental Center of Veterinary Radiology, University of Napoli \u201cFederico II\u201d, Via Federico Delpino 1, 80137 Napoli, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7290-3108","authenticated-orcid":false,"given":"Leonardo","family":"Meomartino","sequence":"additional","affiliation":[{"name":"Interdepartmental Center of Veterinary Radiology, University of Napoli \u201cFederico II\u201d, Via Federico Delpino 1, 80137 Napoli, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,6,9]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/B978-0-12-416021-7.00001-8","article-title":"Pituitary gland development and disease: From stem cell to hormone production","volume":"106","author":"Davis","year":"2013","journal-title":"Curr. 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