{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T00:28:07Z","timestamp":1773016087761,"version":"3.50.1"},"reference-count":41,"publisher":"MDPI AG","issue":"16","license":[{"start":{"date-parts":[[2023,8,8]],"date-time":"2023-08-08T00:00:00Z","timestamp":1691452800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Virbac, Carros, France"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animals"],"abstract":"<jats:p>Background: Deslorelin implant use in cats is a medical alternative to surgical sterilization, and due to its prolonged efficacy, its use has shown growing interest in the veterinary community. In the case of breeding facilities, its removal is often requested for the early restoration of testicular function. As anti-M\u00fcllerian hormones (AMH) in males is dependent of testosterone secretion, its assay may determine the restoration of testicular steroid secretion. An average of 3 weeks has been already described for tomcats\u2019 testicular function resumption after implant removal, but information about AMH concentrations in deslorelin-treated tomcats is lacking. Methods: Fourteen tomcats were treated for temporary suppression of fertility with a 4.7 mg deslorelin implant, which was surgically removed after 3, 6 or 9 months (n = 6, 4 and 4 tomcats, respectively). A general clinical and reproductive check with a gonadorelin stimulation test for testosterone determination was performed before deslorelin implant administration. After implant removal, tomcats\u2019 testicles were ultrasonographically checked for volume determination every 1-2 weeks with observation of the glans penis (presence or absence of spikes) and blood collection to assay both testosterone and AMH concentrations. Results: AMH concentrations increased significantly during the deslorelin treatment from 20.95 \u00b1 4.97 ng\/mL to 82.41 \u00b1 14.59 ng\/mL (p &lt; 0.05). Following implant removal, AMH concentrations progressively decreased to pre-treatment levels, with a value of 28.42 \u00b1 7.98 ng\/mL on the third week post-removal where testosterone secretion was again detected. Conclusions: Even if a big variability of AMH concentrations exists between male individuals, resumption of tomcats\u2019 testicular function following a deslorelin treatment can be determined by AMH assay.<\/jats:p>","DOI":"10.3390\/ani13162552","type":"journal-article","created":{"date-parts":[[2023,8,8]],"date-time":"2023-08-08T12:35:42Z","timestamp":1691498142000},"page":"2552","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Anti-M\u00fcllerian Hormone Concentrations for Determining Resumption of Sertoli Cell Function following Removal of a 4.7 mg Deslorelin Implant in Tomcats"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4994-768X","authenticated-orcid":false,"given":"Lluis","family":"Ferr\u00e9-Dolcet","sequence":"first","affiliation":[{"name":"Department of Animal Medicine, Production and Health, University of Padova, 35122 Padova, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matteo","family":"Bordogna","sequence":"additional","affiliation":[{"name":"Altinia Veterinary Clinic, 30173 Venice, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6586-5035","authenticated-orcid":false,"given":"Barbara","family":"Contiero","sequence":"additional","affiliation":[{"name":"Department of Animal Medicine, Production and Health, University of Padova, 35122 Padova, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1760-6458","authenticated-orcid":false,"given":"Christelle","family":"Fontaine","sequence":"additional","affiliation":[{"name":"Virbac, 13\u00e8me Rue, 06515 Carros, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvia","family":"Bedin","sequence":"additional","affiliation":[{"name":"Department of Animal Medicine, Production and Health, University of Padova, 35122 Padova, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefano","family":"Romagnoli","sequence":"additional","affiliation":[{"name":"Department of Animal Medicine, Production and Health, University of Padova, 35122 Padova, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,8,8]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/0092-8674(86)90783-X","article-title":"Isolation of the Bovine and Human Genes for M\u00fcllerian Inhibiting Substance and Expression of the Human Gene in Animal Cells","volume":"45","author":"Cate","year":"1986","journal-title":"Cell"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1177\/1040638711403428","article-title":"Measurement of Serum Anti-M\u00fcllerian Hormone Concentration in Female Dogs and Cats before and after Ovariohysterectomy","volume":"23","author":"Place","year":"2011","journal-title":"J. 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