{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T22:33:48Z","timestamp":1783031628675,"version":"3.54.6"},"reference-count":40,"publisher":"MDPI AG","issue":"18","license":[{"start":{"date-parts":[[2023,9,20]],"date-time":"2023-09-20T00:00:00Z","timestamp":1695168000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"CNPq (Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico)","award":["315873\/2021-3"],"award-info":[{"award-number":["315873\/2021-3"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animals"],"abstract":"<jats:p>Rabies is a fatal neglected tropical zoonosis, and its significance for domestic herbivores in the rural cycle is probably associated with rainforest deforestation, livestock, and agricultural expansion. This epidemiological survey aimed to study the occurrence of rabies in bovines and equines in the state of Rond\u00f4nia, located in the Brazilian\u2019s Legal Amazon, between the years 2002 and 2021, correlating these findings with the prophylactic strategies adopted by the local sanitary agency for rabies control. During this period, 201 cases were observed in bovines and 23 in equines. A downward trend in rabies incidence was observed for both domestic herbivores. Rabies did not show a higher occurrence in any specific time of the year, and epidemic periods varied during some years for bovines and equines. Using the Generalized estimating equations (GEE) method, a multiple model approach was obtained with the explanatory variables significantly associated with the decrease in rabies incidence in cattle and horses during the study period: the ratio of treated bats and ratio of vaccine doses sold. Furthermore, the ratio of printed educative material was positively associated with rabies incidence. Despite a decreasing trend in rabies occurrences in this Amazon rainforest area, likely due to the actions taken by the animal sanitary agency, rabies remains endemic and requires monitoring, as well as prophylactic strategies to control this disease.<\/jats:p>","DOI":"10.3390\/ani13182974","type":"journal-article","created":{"date-parts":[[2023,9,20]],"date-time":"2023-09-20T21:47:03Z","timestamp":1695246423000},"page":"2974","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Epidemiology and Control of Rabies in Cattle and Equines in Rond\u00f4nia State, a Brazilian\u2019s Legal Amazon Area"],"prefix":"10.3390","volume":"13","author":[{"given":"D\u00e9bora Naihane Alves","family":"Sodr\u00e9","sequence":"first","affiliation":[{"name":"IDARON\u2014Agency of Agrosilvopastoral Sanitary Defense of Rond\u00f4nia State, Cacoal 76964-062, RO, Brazil"},{"name":"Department of Veterinary Medicine, Brazil University (UB), Descalvado 13690-000, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7967-7628","authenticated-orcid":false,"given":"Gabriel Augusto Marques","family":"Rossi","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine, Vila Velha University (UVV), Vila Velha 29102-920, ES, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis Antonio","family":"Mathias","sequence":"additional","affiliation":[{"name":"Department of Pathology, Reproduction and One Health, S\u00e3o Paulo State University (UNESP), Jaboticabal 14884-900, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5845-3940","authenticated-orcid":false,"given":"Marco Antonio","family":"de Andrade Belo","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine, Brazil University (UB), Descalvado 13690-000, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,9,20]]},"reference":[{"key":"ref_1","unstructured":"OIE (2022, May 19). 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