{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T14:34:56Z","timestamp":1783694096141,"version":"3.55.0"},"reference-count":49,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2024,1,24]],"date-time":"2024-01-24T00:00:00Z","timestamp":1706054400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100018646","name":"Mahanakorn University of Technology","doi-asserted-by":"publisher","award":["Immuno-002-2022"],"award-info":[{"award-number":["Immuno-002-2022"]}],"id":[{"id":"10.13039\/501100018646","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animals"],"abstract":"<jats:p>The measurement of serum progesterone often varies due to different laboratory methodologies and individual canine characteristics. In this investigation, serum progesterone outcomes obtained from a commercial point-of-care immunological analyzer, designed for efficient serum progesterone assessment in bitches, were compared with results derived from chemiluminescent microparticle immunoassay from reference laboratories in Thailand. Our thorough documentation encompassed various parameters: mean, standard deviation, 95% confidence interval, and minimum and maximum serum progesterone concentration values. Additionally, we meticulously recorded the Pearson\u2019s correlation coefficient, Lin\u2019s concordance correlation coefficient, and the bias correction factor. Interestingly, there was no significant difference (p &gt; 0.05) in the means obtained by the point-of-care immunological analyzer and chemiluminescent microparticle immunoassay. The Pearson\u2019s correlation coefficient between the point-of-care immunological analyzer and chemiluminescent microparticle immunoassay stood at 0.957, with Lin\u2019s concordance correlation coefficient for point-of-care immunological analyzer recorded as 0.949. Furthermore, the bias correction factor was established at 0.991. This investigation followed established chemiluminescent microparticle immunoassay guidelines, modified to incorporate the mean and 95% confidence interval as criteria for optimal breeding time using the point-of-care immunological analyzer. In conclusion, the commercial point-of-care immunological analyzer emerges as a valuable tool, aiding in precisely determining the optimal timing for natural mating or artificial insemination in bitches.<\/jats:p>","DOI":"10.3390\/ani14030377","type":"journal-article","created":{"date-parts":[[2024,1,24]],"date-time":"2024-01-24T09:57:42Z","timestamp":1706090262000},"page":"377","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["A Precision Assessment of a Point-of-Care Immunological Analyzer for Swift Progesterone Measurement and Guidance for Determining the Optimal Breeding Time in Bitches"],"prefix":"10.3390","volume":"14","author":[{"given":"Thanikran","family":"Suwannachote","sequence":"first","affiliation":[{"name":"Clinic for Small Domestic Animals and Radiology, Mahanakorn University of Technology, Bangkok 10530, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-2595-2384","authenticated-orcid":false,"given":"Supphathat","family":"Wutthiwitthayaphong","sequence":"additional","affiliation":[{"name":"Immunology and Virology Department, Mahanakorn University of Technology, Bangkok 10530, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saengtawan","family":"Arayatham","sequence":"additional","affiliation":[{"name":"Clinic for Gynecology and Animal Reproduction, Mahanakorn University of Technology, Bangkok 10530, Thailand"},{"name":"Animal Biotechnology, Mahanakorn University of Technology, Bangkok 10530, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wisut","family":"Prasitsuwan","sequence":"additional","affiliation":[{"name":"Animal Biotechnology, Mahanakorn University of Technology, Bangkok 10530, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2345-119X","authenticated-orcid":false,"given":"Sakchai","family":"Ruenphet","sequence":"additional","affiliation":[{"name":"Immunology and Virology Department, Mahanakorn University of Technology, Bangkok 10530, Thailand"},{"name":"Animal Biotechnology, Mahanakorn University of Technology, Bangkok 10530, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,1,24]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.anireprosci.2014.11.008","article-title":"Periovulatory time in the bitch: What\u2019s new to know? 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