{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T00:43:14Z","timestamp":1760143394356,"version":"build-2065373602"},"reference-count":20,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2024,2,3]],"date-time":"2024-02-03T00:00:00Z","timestamp":1706918400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animals"],"abstract":"<jats:p>Meningitis is the inflammation of the membranes surrounding the central nervous system and is poorly described in water buffaloes. Five cases of meningitis in adults buffaloes of the Murrah and Mediterranean breads were studied. All buffaloes came from a farm located in the municipality of Castanhal, Par\u00e1, Brazil at different times. Clinical examination showed neurological clinical signs, such as apathy, reluctance to move, spastic paresis especially of the pelvic limbs, hypermetria, difficulty getting up, pressing of the head into obstacles and convulsion. In three buffaloes, a large part of the horn had been lost, exposing the corresponding frontal sinus, through which a bloody to purulent exudate flowed. The hemogram revealed neutrophilic leukocytosis. At necropsy, adherence of the dura mater to the periosteum and a purulent to fibrinopurulent exudate were observed in the sulci of the cerebral cortex and on the pia mater over almost the entire surface of the brain and throughout the spinal cord. The cerebrospinal fluid had a cloudy aspect with fibrin filaments. The histopathology of buffaloes confirmed the diagnosis of bacterial fibrinopurulent meningitis. Buffaloes are susceptible to bacterial inflammation of the meninges due to fractures of the base of the horn and mostly present with neurological manifestations.<\/jats:p>","DOI":"10.3390\/ani14030505","type":"journal-article","created":{"date-parts":[[2024,2,5]],"date-time":"2024-02-05T09:31:58Z","timestamp":1707125518000},"page":"505","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Bacterial Meningitis in Buffaloes in Brazil"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8915-5735","authenticated-orcid":false,"given":"Jos\u00e9 Diomedes","family":"Barbosa","sequence":"first","affiliation":[{"name":"Instituto de Medicina Veterin\u00e1ria, Universidade Federal do Par\u00e1, Castanhal 68740-970, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henrique dos Anjos","family":"Bomjardim","sequence":"additional","affiliation":[{"name":"Faculdade de Medicina Veterin\u00e1ria, Instituto de Estudos do Tr\u00f3pico \u00damido, Universidade Federal do Sul e Sudeste do Par\u00e1 (Unifesspa), Xinguara 68557-335, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7837-4246","authenticated-orcid":false,"given":"Camila Cordeiro","family":"Barbosa","sequence":"additional","affiliation":[{"name":"Instituto de Medicina Veterin\u00e1ria, Universidade Federal do Par\u00e1, Castanhal 68740-970, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos Magno Chaves","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Instituto de Medicina Veterin\u00e1ria, Universidade Federal do Par\u00e1, Castanhal 68740-970, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paulo S\u00e9rgio Chagas da","family":"Costa","sequence":"additional","affiliation":[{"name":"Faculdade Antonio Leite FAL\/UniBTA, Campus Castanhal, Castanhal 68742-000, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-6142-0417","authenticated-orcid":false,"given":"Carlos Eduardo da Silva","family":"Ferreira Filho","sequence":"additional","affiliation":[{"name":"Instituto de Medicina Veterin\u00e1ria, Universidade Federal do Par\u00e1, Castanhal 68740-970, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nat\u00e1lia da Silva e Silva","family":"Silveira","sequence":"additional","affiliation":[{"name":"Instituto de Medicina Veterin\u00e1ria, Universidade Federal do Par\u00e1, Castanhal 68740-970, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcos Dutra","family":"Duarte","sequence":"additional","affiliation":[{"name":"Instituto de Medicina Veterin\u00e1ria, Universidade Federal do Par\u00e1, Castanhal 68740-970, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lu\u00eds Ant\u00f4nio Scalabrin","family":"Tondo","sequence":"additional","affiliation":[{"name":"Departamento de Epidemiologia e Sa\u00fade P\u00fablica (DESP), Instituto de Veterin\u00e1ria (IV), Universidade Federal Rural do Rio de Janeiro (UFRRJ), Serop\u00e9dica 23890-000, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marilene de Farias","family":"Brito","sequence":"additional","affiliation":[{"name":"Departamento de Epidemiologia e Sa\u00fade P\u00fablica (DESP), Instituto de Veterin\u00e1ria (IV), Universidade Federal Rural do Rio de Janeiro (UFRRJ), Serop\u00e9dica 23890-000, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,2,3]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1590\/S0100-736X2005000400011","article-title":"Sinais cl\u00ednicos, distribui\u00e7\u00e3o das les\u00f5es no sistema nervoso e epidemiologia da raiva em herb\u00edvoros na regi\u00e3o Nordeste do Brasil","volume":"25","author":"Lima","year":"2005","journal-title":"Pesq. 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