{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T22:05:54Z","timestamp":1783721154763,"version":"3.55.0"},"reference-count":63,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2024,3,19]],"date-time":"2024-03-19T00:00:00Z","timestamp":1710806400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animals"],"abstract":"<jats:p>The aim of this study was to describe the diagnosis and treatment of grade IV lateral patellar luxation (LPL) in two adult large breed dogs with complex femoral deformities using patient-specific three-dimensionally (3D) printed osteotomy guides and implants. Computed tomography (CT) scans were obtained for virtual surgical planning (VSP) using computer-aided design (CAD) software, which allowed for 3D reconstruction and manipulation of the femoral deformities, providing a preoperative view of the correction. Of the two patients, one was affected bilaterally and the other unilaterally, but both dogs were from the same litter. Therefore, the healthy femur of the unilaterally affected patient was used as the physiological reference for the virtual surgical correction. Three distal femoral trapezoid osteotomies (DF-TO) followed by reduction and internal fixation with plates were performed using patient-specific 3D-printed osteotomy guides and implants. This type of osteotomy permitted correction of procurvatum in all the femurs to increase knee extension, raise the dog\u2019s lumbar spine and correct the kyphosis. Preoperative, expected and postoperative femoral angles were compared to evaluate the efficacy of virtual surgical planning and the outcome of surgical correction. Radiographic follow-up, passive range of motion and functional recovery were recorded. There were no major complications requiring revision surgery. Significant clinical improvement was observed in both patients. This study suggests that the treatment used represents a viable surgical alternative to restore limb alignment in patients with complex femoral deformities.<\/jats:p>","DOI":"10.3390\/ani14060951","type":"journal-article","created":{"date-parts":[[2024,3,19]],"date-time":"2024-03-19T09:39:31Z","timestamp":1710841171000},"page":"951","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Patient-Specific 3D-Printed Osteotomy Guides and Titanium Plates for Distal Femoral Deformities in Dogs with Lateral Patellar Luxation"],"prefix":"10.3390","volume":"14","author":[{"given":"Enrico","family":"Panichi","sequence":"first","affiliation":[{"name":"Centro Traumatologico Ortopedico Veterinario, Via C. Festa 9, 16011 Arenzano, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fulvio","family":"Cappellari","sequence":"additional","affiliation":[{"name":"Centro Traumatologico Ortopedico Veterinario, Via C. Festa 9, 16011 Arenzano, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ekaterina","family":"Burkhan","sequence":"additional","affiliation":[{"name":"Bonabyte, Begovoy Proezd 7, 125284 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaetano","family":"Principato","sequence":"additional","affiliation":[{"name":"Centro Traumatologico Ortopedico Veterinario, Via C. Festa 9, 16011 Arenzano, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Currenti","sequence":"additional","affiliation":[{"name":"Centro Traumatologico Ortopedico Veterinario, Via C. Festa 9, 16011 Arenzano, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-1404-7280","authenticated-orcid":false,"given":"Marco","family":"Tabb\u00ec","sequence":"additional","affiliation":[{"name":"Department of Veterinary Sciences, University of Messina, via Palatucci Annunziata, 98100 Messina, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4846-2581","authenticated-orcid":false,"given":"Francesco","family":"Macr\u00ec","sequence":"additional","affiliation":[{"name":"Department of Veterinary Sciences, University of Messina, via Palatucci Annunziata, 98100 Messina, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,3,19]]},"reference":[{"key":"ref_1","first-page":"23","article-title":"Patellar luxation in dogs","volume":"9","author":"Fatone","year":"2018","journal-title":"Vet. Med."},{"key":"ref_2","first-page":"255","article-title":"Lateral patellar luxation in nine small breed dogs","volume":"6","author":"Balestriere","year":"2016","journal-title":"Open Vet. J."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"130","DOI":"10.3415\/VCOT-13-05-0064","article-title":"Lateral patellar luxation in dogs: A retrospective study of 65 dogs","volume":"27","author":"Kalff","year":"2014","journal-title":"Vet. Comp. Orthop. Traumatol."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"444","DOI":"10.2460\/javma.244.4.444","article-title":"Complications after corrective surgery for lateral patellar luxation in dogs: 36 cases (2000\u20132011)","volume":"244","author":"Shaver","year":"2014","journal-title":"J. Am. Vet. Med. Assoc."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1111\/j.1748-5827.2006.00004.x","article-title":"Patellar luxation in 70 large breed dogs","volume":"47","author":"Gibbons","year":"2006","journal-title":"J. Small Anim. Pract."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1055\/s-0037-1616589","article-title":"Frequency and distribution of patellar luxation in dogs. 134 cases (2000 to 2005)","volume":"20","author":"Alam","year":"2007","journal-title":"Vet. Comp. Orthop. Traumatol."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"467","DOI":"10.5326\/0380467","article-title":"Breed susceptibility for developmental orthopedic diseases in dogs","volume":"38","author":"LaFond","year":"2002","journal-title":"J. Am. Anim. Hosp. Assoc."},{"key":"ref_8","first-page":"292","article-title":"Patellar luxation in dogs and cats: Management and prevention","volume":"24","author":"Montavon","year":"2002","journal-title":"Comp. Cont. Edu. Pract. Vet."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"32","DOI":"10.3415\/VCOT-08-01-0009","article-title":"The prevalence of canine patellar luxation in three centres. Clinical features and radiographic evidence of limb deviation","volume":"22","author":"Bound","year":"2009","journal-title":"Vet. Comp. Orthop. Traumatol."},{"key":"ref_10","first-page":"1037","article-title":"Patellar luxation: Pathogenesis and surgical correction","volume":"47","author":"Harasen","year":"2006","journal-title":"Can. Vet. J."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"416","DOI":"10.3415\/VCOT-15-08-0145","article-title":"Complex angular and torsional deformities (distal femoral malunions). Preoperative planning using stereolithography and surgical correction with locking plate fixation in four dogs","volume":"29","author":"DeTora","year":"2016","journal-title":"Vet. Comp. Orthop. Traumatol."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1111\/j.1532-950X.2006.00189.x","article-title":"Complications associated with corrective surgery for patellar luxation in 109 dogs","volume":"35","author":"Arthurs","year":"2006","journal-title":"Vet. Surg."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1111\/j.1748-5827.2007.00420.x","article-title":"Treatment of medial patellar luxation by femoral closing wedge ostectomy using a distal femoral plate in four dogs","volume":"49","author":"Roch","year":"2008","journal-title":"J. Small Anim. Pract."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"364","DOI":"10.3415\/VCOT-16-05-0073","article-title":"Prevalence, treatment and outcome of patellar luxation in dogs in Italy. A retrospective multicentric study (2009\u20132014)","volume":"30","author":"Bosio","year":"2017","journal-title":"Vet. Comp. Orthop. Traumatol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"20","DOI":"10.3415\/VCOT-16-07-0103","article-title":"Distal femoral lateral closing wedge osteotomy as a component of comprehensive treatment of medial patellar luxation and distal femoral varus in dogs","volume":"30","author":"Brower","year":"2017","journal-title":"Vet. Comp. Orthop. Traumatol."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"426","DOI":"10.3415\/VCOT-15-11-0186","article-title":"Distal femoral osteotomy using a novel deformity reduction device","volume":"29","author":"Panichi","year":"2016","journal-title":"Vet. Comp. Orthop. Traumatol."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"1070","DOI":"10.2460\/javma.231.7.1070","article-title":"Long-term outcome of distal femoral osteotomy for treatment of combined distal femoral varus and medial patellar luxation: 12 cases (1999\u20132004)","volume":"231","author":"Swiderski","year":"2007","journal-title":"J. Am. Vet. Med. Assoc."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"e427","DOI":"10.1097\/BPO.0000000000002104","article-title":"3D-printed Cutting Guides for Lower Limb Deformity Correction in the Young Population","volume":"42","author":"Gigi","year":"2022","journal-title":"J. Pediatr. Orthop."},{"key":"ref_19","doi-asserted-by":"crossref","unstructured":"Oraa, J., Beitia, M., Fiz, N., Gonz\u00e1lez, S., S\u00e1nchez, X., Delgado, D., and S\u00e1nchez, M. (2021). Custom 3D-Printed Cutting Guides for Femoral Osteotomy in Rotational Malalignment Due to Diaphyseal Fractures: Surgical Technique and Case Series. J. Clin. Med., 10.","DOI":"10.3390\/jcm10153366"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"400","DOI":"10.21037\/atm.2017.07.03","article-title":"Application of 3D Technology and Printing for Femoral Derotation Osteotomy: Case and Technical Report","volume":"5","author":"Fiz","year":"2017","journal-title":"Ann. Transl. Med."},{"key":"ref_21","first-page":"57","article-title":"3D-Printed Patient-Specific Applications in Orthopedics","volume":"8","author":"Wong","year":"2016","journal-title":"Orthop. Res. Rev."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1007\/s11596-013-1131-x","article-title":"Computer-Aided Design and Custom-Made Guide in Corrective Osteotomy for Complex Femoral Deformity","volume":"33","author":"Chai","year":"2013","journal-title":"J. Huazhong Univ. Sci. Technol. Med. Sci."},{"key":"ref_23","doi-asserted-by":"crossref","unstructured":"Memarian, P., Pishavar, E., Zanotti, F., Trentini, M., Camponogara, F., Soliani, E., Gargiulo, P., Isola, M., and Zavan, B. (2022). Active Materials for 3D Printing in Small Animals: Current Modalities and Future Directions for Orthopedic Applications. Int. J. Mol. Sci., 23.","DOI":"10.3390\/ijms23031045"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"104960","DOI":"10.1016\/j.rvsc.2023.104960","article-title":"Orthotics and prosthetics by 3D-printing: Accelerating its fabrication flow","volume":"162","year":"2023","journal-title":"Res. Vet. Sci."},{"key":"ref_25","first-page":"1","article-title":"Accuracy of virtual surgical planning and custom three-dimensionally printed osteotomy and reduction guides for acute uni- and biapical correction of antebrachial deformities in dogs","volume":"260","author":"Lewis","year":"2022","journal-title":"J. Am. Vet. Med. Assoc."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1111\/vsu.13876","article-title":"Proximal femoral deformity correction and total hip arthroplasty in a dog using 3D printed custom guides","volume":"52","author":"Carvajal","year":"2023","journal-title":"Vet. Surg."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1055\/s-0040-1709702","article-title":"Three-dimensional-printed patient-specific osteotomy guides, repositioning guides and titanium plates for acute correction of antebrachial limb deformities in dogs","volume":"34","author":"Carwardine","year":"2021","journal-title":"Vet. Comp. Orthop. Traumatol."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1111\/vsu.13126","article-title":"Accuracy of patientspecific three-dimensional-printed osteotomy and reduction guides for distal femoral osteotomy in dogs with medial patella luxation","volume":"48","author":"Hall","year":"2019","journal-title":"Vet. Surg."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"230","DOI":"10.3415\/VCOT-16-10-0144","article-title":"Bilateral shoulder arthrodesis in a Pekinese using three-dimensional printed patient-specific osteotomy and reduction guides","volume":"30","author":"Oxley","year":"2017","journal-title":"Vet. Comp. Orthop. Traumatol."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1111\/vsu.13963","article-title":"3D-printed, patient-specific cutting guides improve femoral and tibial cut alignment in canine total knee replacement","volume":"52","author":"Fracka","year":"2023","journal-title":"Vet. Surg."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"473","DOI":"10.17236\/sat00216","article-title":"Three-dimensional computer-assisted corrective osteotomy with a patient-specific surgical guide for an antebrachial limb deformity in two dogs","volume":"161","author":"Longo","year":"2019","journal-title":"Schweiz. Arch. Tierheilkd."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"1126","DOI":"10.1111\/vsu.13882","article-title":"Three-dimensional volume rendering planning, surgical treatment, and clinical outcomes for femoral and tibial detorsional osteotomies in dogs","volume":"51","author":"Longo","year":"2022","journal-title":"Vet. Surg."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1007\/s00264-018-4043-3","article-title":"Three dimensional patient-specific printed cutting guides for closing-wedge distal femoral osteotomy","volume":"43","author":"Shi","year":"2019","journal-title":"Int. Orthop."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1055\/s-0039-1678701","article-title":"Computer-Assisted Surgery Using 3D Printed Saw Guides for Acute Correction of Antebrachial Angular Limb Deformities in Dogs","volume":"32","author":"Worth","year":"2019","journal-title":"Vet. Comp. Orthop. Traumatol."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1007\/s13534-018-00092-7","article-title":"Additive manufacturing to veterinary practice: Recovery of bony defects after the osteosarcoma resection in canines","volume":"9","author":"Popov","year":"2019","journal-title":"Biomed. Eng. Lett."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1111\/vsu.13346","article-title":"Accuracy of threedimensional printed patient-specific drill guides for treatment of canine humeral intracondylar fissure","volume":"49","author":"Easter","year":"2020","journal-title":"Vet. Surg."},{"key":"ref_37","first-page":"e12","article-title":"Three-dimensional computer-assisted surgical planning and use of three-dimensional printing in the repair of a complex articular femoral fracture in a dog","volume":"1","author":"Lam","year":"2018","journal-title":"Vet. Comp. Orthop. Traumatol."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1111\/vsu.12776","article-title":"A 3-dimensional-printed patient-specific guide system for minimally invasive plate osteosynthesis of a comminuted mid-diaphyseal humeral fracture in a cat","volume":"47","author":"Oxley","year":"2018","journal-title":"Vet. Surg."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1111\/jsap.13188","article-title":"Atlanto-axial ventral stabilisation using 3D-printed patient-specific drill guides for placement of bicortical screws in dogs","volume":"61","author":"Toni","year":"2020","journal-title":"J. Small Anim. Pract."},{"key":"ref_40","doi-asserted-by":"crossref","unstructured":"Kamishina, H., Sugawara, T., Nakata, K., Nishida, H., Yada, N., Fujioka, T., Nagata, Y., Doi, A., Konno, N., and Uchida, F. (2019). Clinical application of 3D printing technology to the surgical treatment of atlantoaxial subluxation in small breed dogs. PLoS ONE, 14.","DOI":"10.1371\/journal.pone.0216445"},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1055\/s-0040-1716840","article-title":"Accuracy of placement of pedicle screws in the lumbosacral region of dogs using 3Dprinted patient-specific drill guides","volume":"34","author":"Toni","year":"2021","journal-title":"Vet. Comp. Orthop. Traumatol."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1111\/vsu.12734","article-title":"Accuracy of a patient-specific 3D printed drill guide for placement of cervical transpedicular screws","volume":"47","author":"Oxley","year":"2018","journal-title":"Vet. Surg."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1111\/j.1740-8261.2006.00184.x","article-title":"Radiographic and computed tomographic determination of femoral varus and torsion in the dog","volume":"47","author":"Dudley","year":"2006","journal-title":"Vet. Radiol. Ultrasound"},{"key":"ref_44","doi-asserted-by":"crossref","unstructured":"Paley, D., and Herzenberg, J.E. (2002). Principles of Deformity Correction, Springer.","DOI":"10.1007\/978-3-642-59373-4"},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1111\/jsap.12533","article-title":"Pilot study measuring the effects of bandaging and cold compression therapy following tibial plateau levelling osteotomy","volume":"57","author":"Kieves","year":"2016","journal-title":"J. Small Anim. Pract."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"1284","DOI":"10.2460\/javma.238.10.1284","article-title":"Effect of cold compression therapy on postoperative pain, swelling, range of motion, and lameness after tibial plateau leveling osteotomy in dogs","volume":"238","author":"Drygas","year":"2011","journal-title":"J. Am. Vet. Med. Assoc."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"381","DOI":"10.3389\/fvets.2020.00381","article-title":"Cryotherapy Improves Limb Use but Delays Normothermia Early After Stifle Joint Surgery in Dogs","volume":"7","author":"Szabo","year":"2020","journal-title":"Front. Vet. Sci."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1111\/j.1532-950X.2005.00114.x","article-title":"Principles of uniapical and biapical radial deformity correction using dome osteotomies and the center of rotation of angulation methodology in dogs","volume":"35","author":"Fox","year":"2006","journal-title":"Vet. Surg."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1111\/vsu.12460","article-title":"Classification of angular limb deformities affecting the canine radius and ulna using the center of rotation of angulation method","volume":"45","author":"Knapp","year":"2016","journal-title":"Vet. Surg."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1111\/j.1532-950X.2008.00399.x","article-title":"Validation of a technique to assess radial torsion in the presence of procurvatum and valgus deformity using computed tomography: A cadaveric study","volume":"37","author":"Meola","year":"2008","journal-title":"Vet. Surg."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"89","DOI":"10.3415\/VCOT-10-09-0135","article-title":"Effects of antebrachial torsion on the measurement of angulation in the frontal plane: A cadaveric radiographic analysis","volume":"25","author":"Piras","year":"2012","journal-title":"Vet. Comp. Orthop. Traumatol."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1111\/vsu.13438","article-title":"A computed tomographic graphical approach to guide correction of femoral torsion","volume":"49","author":"Eby","year":"2020","journal-title":"Vet. Surg."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1111\/j.1532-950X.2013.12032.x","article-title":"Precision of a novel computed tomographic method for quantification of femoral varus in dogs and an assessment of the effect of femoral malpositioning","volume":"42","author":"Oxley","year":"2013","journal-title":"Vet. Surg."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1111\/j.1532-950X.2014.12265.x","article-title":"Repeatability and reproducibility of measurements of femoral and tibial alignment using computed tomography multiplanar reconstructions","volume":"44","author":"Barnes","year":"2015","journal-title":"Vet. Surg."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1111\/j.1532-950X.2007.00309.x","article-title":"Measurement of femoral angles in four dog breeds","volume":"36","author":"Tomlinson","year":"2007","journal-title":"Vet. Surg."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.cvsm.2014.09.004","article-title":"Principles and application of range of motion and stretching in companion animals","volume":"45","author":"Levine","year":"2015","journal-title":"Vet. Clin. N. Am. Small Anim. Pract."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1080\/00480169.2020.1722271","article-title":"Rehabilitation of companion animals following orthopaedic surgery","volume":"68","author":"Baltzer","year":"2020","journal-title":"N. Z. Vet. J."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.cvsm.2014.09.005","article-title":"Principles and applications of therapeutic exercises for small animals","volume":"45","author":"Drum","year":"2015","journal-title":"Vet. Clin. N. Am. Small Anim. Pract."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1111\/vsu.13968","article-title":"Comparison of three-dimensional printed patient-specific guides versus freehand approach for radial osteotomies in normal dogs: Ex vivo model","volume":"53","author":"Townsend","year":"2024","journal-title":"Vet. Surg."},{"key":"ref_60","doi-asserted-by":"crossref","unstructured":"Lee, H.R., Adam, G.O., Yang, D.K., Tungalag, T., Lee, S.J., Kim, J.S., Kang, H.S., Kim, S.J., and Kim, N.S. (2020). An Easy and Economical Way to Produce a Three-Dimensional Bone Phantom in a Dog with Antebrachial Deformities. Animals, 10.","DOI":"10.3390\/ani10091445"},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"28","DOI":"10.3415\/VCOT-16-06-0086","article-title":"Comparison of osteotomy technique and jig type in completion of distal femoral osteotomies for correction of medial patellar luxation: An in vitro study","volume":"30","author":"Olimpo","year":"2017","journal-title":"Vet. Comp. Orthop. Traumatol."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1111\/vru.12176","article-title":"Invited review\u2014Applications for 3D printers in veterinary medicine","volume":"55","author":"Hespel","year":"2014","journal-title":"Vet. Radiol. Ultrasound"},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1111\/ans.13533","article-title":"Three-dimensional printing in orthopaedic surgery: Review of current and future applications","volume":"86","author":"Mulford","year":"2016","journal-title":"ANZ J. Surg."}],"container-title":["Animals"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2076-2615\/14\/6\/951\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T14:16:03Z","timestamp":1760105763000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2076-2615\/14\/6\/951"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,19]]},"references-count":63,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2024,3]]}},"alternative-id":["ani14060951"],"URL":"https:\/\/doi.org\/10.3390\/ani14060951","relation":{},"ISSN":["2076-2615"],"issn-type":[{"value":"2076-2615","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3,19]]}}}