{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T01:40:12Z","timestamp":1788918012977,"version":"build-2803163510"},"reference-count":90,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2024,3,29]],"date-time":"2024-03-29T00:00:00Z","timestamp":1711670400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National Institutes of Health","award":["P01CA207206"],"award-info":[{"award-number":["P01CA207206"]}]},{"name":"National Institutes of Health","award":["R01CA139099"],"award-info":[{"award-number":["R01CA139099"]}]},{"name":"National Institutes of Health","award":["R01CA276233"],"award-info":[{"award-number":["R01CA276233"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animals"],"abstract":"<jats:p>Magnetic resonance imaging (MRI) is used pervasively in veterinary practice for the antemortem diagnosis of intracranial tumors. Here, we provide an illustrated summary of the published MRI features of primary and secondary intracranial tumors of dogs and cats, following PRISMA scoping review guidelines. The PubMed and Web of Science databases were searched for relevant records, and input from stakeholders was solicited to select data for extraction. Sixty-seven studies of moderate to low-level evidence quality describing the MRI features of pathologically confirmed canine and feline brain tumors met inclusion criteria. Considerable variability in data inclusion and reporting, as well as low case numbers, prohibited comparative data analyses. Available data support a holistic MRI approach incorporating lesion number, location within the brain, shape, intrinsic signal appearances on multiparametric sequences, patterns of contrast enhancement, and associated secondary changes in the brain to prioritize differential imaging diagnoses, and often allows for accurate presumptive diagnosis of common intracranial tumors. Quantitative MRI techniques show promise for improving discrimination of neoplastic from non-neoplastic brain lesions, as well as differentiating brain tumor types and grades, but sample size limitations will likely remain a significant practical obstacle to the design of robustly powered radiomic studies. For many brain tumor variants, particularly in cats, there remains a need for standardized studies that correlate clinicopathologic and neuroimaging data.<\/jats:p>","DOI":"10.3390\/ani14071044","type":"journal-article","created":{"date-parts":[[2024,3,31]],"date-time":"2024-03-31T13:28:00Z","timestamp":1711891680000},"page":"1044","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["An Illustrated Scoping Review of the Magnetic Resonance Imaging Characteristics of Canine and Feline Brain Tumors"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-3222-8064","authenticated-orcid":false,"given":"James L.","family":"May","sequence":"first","affiliation":[{"name":"Veterinary and Comparative Neuro-Oncology Laboratory, Department of Small Animal Clinical Sciences, Virginia-Maryland College of Veterinary Medicine, Virginia Tech, Blacksburg, VA 24061, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6284-6210","authenticated-orcid":false,"given":"Josefa","family":"Garcia-Mora","sequence":"additional","affiliation":[{"name":"Veterinary and Comparative Neuro-Oncology Laboratory, Department of Small Animal Clinical Sciences, Virginia-Maryland College of Veterinary Medicine, Virginia Tech, Blacksburg, VA 24061, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3606-675X","authenticated-orcid":false,"given":"Michael","family":"Edwards","sequence":"additional","affiliation":[{"name":"Department of Small Animal Clinical Sciences, Virginia-Maryland College of Veterinary Medicine, Virginia Tech, Blacksburg, VA 24061, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1655-7076","authenticated-orcid":false,"given":"John H.","family":"Rossmeisl","sequence":"additional","affiliation":[{"name":"Veterinary and Comparative Neuro-Oncology Laboratory, Department of Small Animal Clinical Sciences, Virginia-Maryland College of Veterinary Medicine, Virginia Tech, Blacksburg, VA 24061, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,3,29]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.3389\/fonc.2019.01151","article-title":"Canine primary intracranial cancer: A clinicopathologic and comparative review of glioma, meningioma, and choroid plexus tumors","volume":"9","author":"Miller","year":"2019","journal-title":"Front. Oncol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1111\/j.1939-1676.2006.tb02913.x","article-title":"Canine intracranial primary neoplasia: 173 cases (1986\u20132003)","volume":"20","author":"Snyder","year":"2006","journal-title":"J. Vet. Intern. Med."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1111\/j.1939-1676.2003.tb02525.x","article-title":"Feline intracranial neoplasia: Retrospective review of 160 cases (1985\u20132001)","volume":"17","author":"Troxel","year":"2003","journal-title":"J. Vet. Int. Med."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1111\/j.1939-1676.2007.0002.x","article-title":"Secondary intracranial neoplasia in the dog: 177 cases (1986\u20132003)","volume":"22","author":"Snyder","year":"2008","journal-title":"J. Vet. Int. Med."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"2021","DOI":"10.1111\/jvim.15885","article-title":"Risk factors for adverse events occurring after recovery from stereotactic brain biopsy in dogs with primary intracranial neoplasia","volume":"34","author":"Shinn","year":"2020","journal-title":"J. Vet. Intern. Med."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1111\/vru.13098","article-title":"Can MRI differentiate between ring-enhancing gliomas and intra-axial abscesses?","volume":"63","author":"Carloni","year":"2022","journal-title":"Vet. Radiol. Ultrasound"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1111\/vru.12137","article-title":"Evaluation of standard magnetic resonance characteristics used to differentiate neoplastic, inflammatory, and vascular brain lesions in dogs","volume":"55","author":"Young","year":"2014","journal-title":"Vet. Radiol. Ultrasound"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1111\/j.1740-8261.2010.01749.x","article-title":"Comparative magnetic resonance imaging findings between gliomas and presumed cerebrovascular accidents in dogs","volume":"52","author":"Cervera","year":"2011","journal-title":"Vet. Radiol. Ultrasound"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1111\/j.1939-1676.2004.tb00158.x","article-title":"Magnetic resonance imaging features of feline intracranial neoplasia: Retrospective analysis of 46 cats","volume":"18","author":"Troxel","year":"2004","journal-title":"J. Vet. Intern. Med."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.tvjl.2009.10.011","article-title":"Magnetic resonance imaging findings in 40 dogs with histologically confirmed intracranial tumours","volume":"187","author":"Pumarola","year":"2011","journal-title":"Vet. J."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1111\/j.1939-1676.2012.00899.x","article-title":"Magnetic resonance imaging for the differentiation of neoplastic, inflammatory, and cerebrovascular brain disease in dogs","volume":"26","author":"Wolff","year":"2012","journal-title":"J. Vet. Int. Med."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"S52","DOI":"10.1111\/j.1740-8261.2010.01785.x","article-title":"Magnetic resonance imaging features of canine intracranial neoplasia","volume":"52","author":"Wisner","year":"2011","journal-title":"Vet. Radiol. Ultrasound"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.tvjl.2011.10.008","article-title":"Canine and feline intracranial meningiomas: An updated review","volume":"192","author":"Motta","year":"2012","journal-title":"Vet. J."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/j.tvjl.2015.01.025","article-title":"Magnetic resonance imaging diagnosis of brain tumors in dogs","volume":"205","author":"Bentley","year":"2015","journal-title":"Vet. J."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1080\/1364557032000119616","article-title":"Scoping studies: Towards a methodological framework","volume":"8","author":"Arksey","year":"2005","journal-title":"Int. J. Soc. Res. Methodol."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"467","DOI":"10.7326\/M18-0850","article-title":"PRISMA Extension for Scoping Reviews (PRISMA-ScR): Checklist and Explanation","volume":"169","author":"Tricco","year":"2018","journal-title":"Ann. Intern. Med."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"S2","DOI":"10.1111\/j.1740-8261.2010.01779.x","article-title":"Growth of clinical veterinary magnetic resonance imaging","volume":"52","author":"Gavin","year":"2011","journal-title":"Vet. Radiol. Ultrasound"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1111\/j.1476-5829.2011.00305.x","article-title":"DCE-MRI: A review and applications in veterinary oncology","volume":"11","author":"Boss","year":"2013","journal-title":"Vet. Comp. Oncol."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"100467","DOI":"10.1016\/j.ejro.2022.100467","article-title":"Imaging techniques in veterinary medicine. Part II: Computed tomography, magnetic resonance imaging, nuclear medicine","volume":"10","author":"Greco","year":"2022","journal-title":"Eur. J. Radiol. Open"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.cvsm.2009.09.006","article-title":"MRI of brain disease in veterinary patients part 2: Acquired brain disorders","volume":"40","author":"Hecht","year":"2010","journal-title":"Vet. Clin. N. Am. Small Anim. Pract."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1016\/j.cvsm.2007.06.004","article-title":"Advanced imaging for veterinary cancer patients","volume":"37","author":"LeBlanc","year":"2007","journal-title":"Vet. Clin. N. Am. Small Anim. Pract."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1111\/j.1740-8261.2001.tb00896.x","article-title":"Magnetization transfer imaging of the canine brain: A review","volume":"42","author":"Vite","year":"2001","journal-title":"Vet. Radiol. Ultrasound"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1002\/jrsm.1563","article-title":"Citationchaser: A tool for transparent and efficient forward and backward citations chasing in systematic searching searching","volume":"13","author":"Haddaway","year":"2022","journal-title":"Res. Synth. Methods"},{"key":"ref_24","unstructured":"(2021, September 23). Veterinary Information Network Survey, MRI Imaging Practices for Dogs and Cats with Intracranial Disease. Available online: https:\/\/surveys.vin.com\/s3\/MRI-Imaging-Practices-for-Dogs-and-Cats-with-Intracranial-Disease."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"982","DOI":"10.2460\/ajvr.75.11.982","article-title":"Multivoxel proton magnetic resonance spectroscopy of inflammatory and neoplastic lesions of the canine brain at 3.0 T","volume":"75","author":"Stadler","year":"2014","journal-title":"Am. J. Vet. Res."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"614026","DOI":"10.3389\/fvets.2020.614026","article-title":"Comparison of Canine and Feline Meningiomas Using the Apparent Diffusion Coefficient and Fractional Anisotropy","volume":"7","author":"Wada","year":"2021","journal-title":"Front. Vet. Sci."},{"key":"ref_27","unstructured":"(2024, January 10). Oxford Centre for Evidence-Based Medicine\u2014Levels of Evidence. Available online: https:\/\/www.cebm.ox.ac.uk\/resources\/levels-of-evidence\/oxford-centre-for-evidence-based-medicine-levels-of-evidence-march-2009."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"2656","DOI":"10.1007\/s00259-019-04372-x","article-title":"Towards clinical application of image mining: A systematic review on artificial intelligence and radiomics","volume":"46","author":"Sollini","year":"2019","journal-title":"Eur. J. Nucl. Med. Mol. Imaging"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1111\/j.1748-5827.2011.01131.x","article-title":"Canine intracranial neoplasia: Clinical risk factors for development of epileptic seizures","volume":"52","author":"Schwartz","year":"2011","journal-title":"J. Small Anim. Pract."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1111\/j.1439-0442.2004.00633.x","article-title":"Diagnostic correlation of CT-MRI and histopathology in 10 dogs with brain neoplasms","volume":"51","author":"Polizopoulou","year":"2004","journal-title":"J. Vet. Med. A Physiol. Pathol. Clin. Med."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1111\/j.1939-1676.1997.tb00094.x","article-title":"Retrospective review of 50 canine intracranial tumors evaluated by magnetic resonance imaging","volume":"11","author":"Kraft","year":"1997","journal-title":"J. Vet. Intern. Med."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1111\/j.1740-8261.1996.tb00807.x","article-title":"Magnetic resonance imaging features of primary brain tumors in dogs","volume":"37","author":"Thomas","year":"1996","journal-title":"Vet. Radiol. Ultrasound"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1111\/jvim.16431","article-title":"Relationship between histological tumor margins and magnetic resonance imaging signal intensities in brain neoplasia of dogs","volume":"36","author":"Johnson","year":"2022","journal-title":"J. Vet. Intern. Med."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1111\/vru.12962","article-title":"Classification of neoplastic and inflammatory brain disease using MRI texture analysis in 119 dogs","volume":"62","author":"Wanamaker","year":"2021","journal-title":"Vet. Radiol. Ultrasound"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"71","DOI":"10.2460\/javma.255.1.71","article-title":"Evaluation of diffusion-weighted magnetic resonance imaging at 3.0 Tesla for differentiation between intracranial neoplastic and noninfectious inflammatory lesions in dogs","volume":"255","author":"Maclellan","year":"2019","journal-title":"J. Am. Vet. Med. Assoc."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"452","DOI":"10.2460\/ajvr.77.5.452","article-title":"Evaluation of intracranial neoplasia and noninfectious meningoencephalitis in dogs by use of short echo time, single voxel proton magnetic resonance spectroscopy at 3.0 Tesla","volume":"77","author":"Carrera","year":"2016","journal-title":"Am. J. Vet. Res."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1111\/j.1740-8261.2010.01764.x","article-title":"Magnetic resonance imaging apparent diffusion coefficients for histologically confirmed intracranial lesions in dogs","volume":"52","author":"King","year":"2011","journal-title":"Vet. Radiol. Ultrasound"},{"key":"ref_38","first-page":"122","article-title":"Dynamic contrast-enhanced magnetic resonance imaging of canine brain tumors","volume":"51","author":"Zhao","year":"2010","journal-title":"Vet. Radiol. Ultrasound"},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1111\/vru.13311","article-title":"Computed tomographic, magnetic resonance imaging, and ultrasonographic characteristics of retrobulbar meningiomas in 15 dogs","volume":"64","author":"Sidhu","year":"2023","journal-title":"Vet. Radiol. Ultrasound"},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1111\/j.1740-8261.1996.tb01227.x","article-title":"Low field magnetic resonance imaging characteristics of cranial vault meningiomas in 13 dogs","volume":"37","author":"Hathcock","year":"1996","journal-title":"Vet. Radiol. Ultrasound"},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1292\/jvms.20-0111","article-title":"Incidence and type of brain herniation associated with intracranial meningioma in dogs and cats","volume":"83","author":"Minato","year":"2021","journal-title":"J. Vet. Med. Sci."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1111\/vru.12814","article-title":"Atypical and malignant canine intracranial meningiomas may have lower apparent diffusion coefficient values than benign tumors","volume":"61","author":"Fages","year":"2020","journal-title":"Vet. Radiol. Ultrasound"},{"key":"ref_43","doi-asserted-by":"crossref","unstructured":"Frank, L., Burigk, L., Lehmbecker, A., Wohlsein, P., Sch\u00fctter, A., Meyerhoff, N., Tipold, A., and Nessler, J. (2020). Meningioma and associated cerebral infarction in three dogs. BMC Vet. Res., 16.","DOI":"10.1186\/s12917-020-02388-2"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.2460\/ajvr.78.10.1156","article-title":"Texture analysis of magnetic resonance images to predict histologic grade of meningiomas in dogs","volume":"78","author":"Banzato","year":"2017","journal-title":"Am. J. Vet. Res."},{"key":"ref_45","doi-asserted-by":"crossref","unstructured":"Banzato, T., Bernardini, M., Cherubini, G.B., and Zotti, A. (2018). A methodological approach for deep learning to distinguish between meningiomas and gliomas on canine MR-images. BMC Vet. Res., 14.","DOI":"10.1186\/s12917-018-1638-2"},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.tvjl.2018.04.001","article-title":"Development of a deep convolutional neural network to predict grading of canine meningiomas from magnetic resonance images","volume":"235","author":"Banzato","year":"2018","journal-title":"Vet. J."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"331","DOI":"10.5326\/JAAHA-MS-5774","article-title":"Clinical and MRI findings in three dogs with polycystic meningiomas","volume":"48","author":"James","year":"2012","journal-title":"J. Am. Anim. Hosp. Assoc."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1111\/j.1939-1676.2008.00042.x","article-title":"Magnetic resonance imaging and histological classification of intracranial meningiomas in 112 dogs","volume":"22","author":"Sturges","year":"2008","journal-title":"J. Vet. Intern Med."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.jfms.2006.07.001","article-title":"Multiple meningiomas: Clinical, radiological, surgical, and pathological findings with outcome in four cats","volume":"9","author":"Forterre","year":"2007","journal-title":"J. Feline Med. Surg."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"43","DOI":"10.5326\/15473317-36-1-43","article-title":"A modified bilateral transfrontal sinus approach to the canine frontal lobe and olfactory bulb: Surgical technique and five cases","volume":"36","author":"Glass","year":"2000","journal-title":"J. Am. Anim. Hosp. Assoc."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1111\/j.1740-8261.1998.tb01609.x","article-title":"The dural tail sign in the diagnosis of meningiomas","volume":"39","author":"Graham","year":"1998","journal-title":"Vet. Radiol. Ultrasound"},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1111\/vru.13038","article-title":"High-field MRI using standard pulse sequences has moderate to substantial interobserver agreement and good accuracy for differentiation between intracranial extra-axial histiocytic sarcoma and meningioma in dogs","volume":"63","author":"Mai","year":"2022","journal-title":"Vet. Radiol. Ultrasound"},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.2460\/javma.248.10.1139","article-title":"Comparison of conventional magnetic resonance imaging and nonenhanced three dimensional time-of-flight magnetic resonance angiography findings between dogs with meningioma and dogs with intracranial histiocytic sarcoma: 19 cases (2010\u20132014)","volume":"248","author":"Ishikawa","year":"2016","journal-title":"J. Am. Vet. Med. Assoc."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1111\/vru.12497","article-title":"Comparisons among MRI signs, apparent diffusion coefficient, and fractional anisotropy in dogs with a solitary intracranial meningioma or histiocytic sarcoma","volume":"58","author":"Wada","year":"2017","journal-title":"Vet. Radiol. Ultrasound"},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1111\/jvim.12554","article-title":"Histiocytic sarcoma with central nervous system involvement in dogs: 19 cases (2006\u20132012)","volume":"29","author":"Mariani","year":"2015","journal-title":"J. Vet. Intern. Med."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1111\/j.1740-8261.2009.01512.x","article-title":"MR imaging of histiocytic sarcoma of the canine brain","volume":"50","author":"Tamura","year":"2009","journal-title":"Vet. Radiol. Ultrasound"},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1111\/jvim.16350","article-title":"Clinical and magnetic resonance imaging features of lymphoma involving the nervous system in cats","volume":"36","author":"Durand","year":"2022","journal-title":"J. Vet. Intern. Med."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1111\/jsap.13324","article-title":"MRI of CNS lymphoma with choroid plexus involvement in five dogs and one cat","volume":"62","author":"Lampe","year":"2021","journal-title":"J. Small Anim. Pract."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1111\/j.1740-8261.2011.01872.x","article-title":"MRI features of CNS lymphoma in dogs and cats","volume":"53","author":"Palus","year":"2012","journal-title":"Vet. Radiol. Ultrasound"},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1111\/vru.13165","article-title":"MRI ischemic and hemorrhagic lesions in arterial and venous territories characterize central nervous system intravascular lymphoma in dogs","volume":"64","author":"Mattei","year":"2023","journal-title":"Vet. Radiol. Ultrasound"},{"key":"ref_61","doi-asserted-by":"crossref","unstructured":"Mayor, C., Verd\u00e9s, J., Alomar, J., Novellas, R., Pumarola, M., and A\u00f1or, S. (2023). Intracranial granular cell tumours in three dogs: Atypical magnetic resonance imaging features and immunohistochemical study. Vet. Sci., 10.","DOI":"10.3390\/vetsci10020134"},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1111\/vru.12027","article-title":"Magnetic resonance imaging features of intracranial granular cell tumors in six dogs","volume":"54","author":"Anwer","year":"2013","journal-title":"Vet. Radiol. Ultrasound"},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1111\/vsu.13917","article-title":"Clinical characteristics and outcome in 15 dogs treated with transsphenoidal hypophysectomy for nonfunctional sellar masses","volume":"52","author":"Hyde","year":"2023","journal-title":"Vet. Surg."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1111\/jsap.12474","article-title":"A magnetic resonance imaging-based classification system for indication of transsphenoidal hypophysectomy in canine pituitary-dependent hypercortisolism","volume":"57","author":"Sato","year":"2016","journal-title":"J. Small Anim. Pract."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1111\/j.1939-1676.2009.0414.x","article-title":"Cross-sectional imaging characteristics of pituitary adenomas, invasive adenomas and adenocarcinomas in dogs: 33 cases (1988\u20132006)","volume":"24","author":"Pollard","year":"2010","journal-title":"J. Vet. Intern. Med."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.1111\/jvim.16749","article-title":"The T2-FLAIR mismatch sign as an imaging biomarker for oligodendrogliomas in dogs","volume":"37","author":"Parker","year":"2023","journal-title":"J. Vet. Intern. Med."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1111\/vru.13253","article-title":"The \u201cClaw Sign\u201d may aid in axial localization in cases of peripherally located canine glioma on MRI","volume":"64","author":"Glamann","year":"2023","journal-title":"Vet. Radiol. Ultrasound"},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1111\/vru.13242","article-title":"Machine learning predicts histologic type and grade of canine gliomas based on MRI texture analysis","volume":"64","author":"Barge","year":"2023","journal-title":"Vet. Radiol. Ultrasound"},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"2104","DOI":"10.1111\/jvim.16519","article-title":"Grading of oligodendroglioma in dogs based on magnetic resonance imaging","volume":"36","author":"Amphimaque","year":"2022","journal-title":"J. Vet. Intern. Med."},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"1902","DOI":"10.1111\/jvim.16199","article-title":"Clinical features, diagnosis, and survival analysis of dogs with glioma","volume":"35","author":"Manzanilla","year":"2021","journal-title":"J. Vet. Intern. Med."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"650320","DOI":"10.3389\/fvets.2021.650320","article-title":"Cerebrospinal fluid drop metastases of canine glioma: Magnetic resonance imaging classification","volume":"8","author":"Bentley","year":"2021","journal-title":"Front. Vet. Sci."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1111\/vru.12570","article-title":"Magnetic resonance imaging features of canine gliomatosis cerebri","volume":"59","author":"Henke","year":"2018","journal-title":"Vet. Radiol. Ultrasound"},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1111\/vru.12464","article-title":"Magnetic resonance imaging features of intraventricular ependymomas in five cats","volume":"58","author":"DeJesus","year":"2017","journal-title":"Vet. Radiol. Ultrasound"},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"157","DOI":"10.3389\/fvets.2017.00157","article-title":"Computed tomography and magnetic resonance imaging are equivalent in mensuration and similarly inaccurate in grade and type predictability of canine intracranial gliomas","volume":"4","author":"Stadler","year":"2017","journal-title":"Front. Vet. Sci."},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"40","DOI":"10.3389\/fvets.2016.00040","article-title":"Canine butterfly glioblastomas: A neuroradiological review","volume":"3","author":"Rossmeisl","year":"2016","journal-title":"Front. Vet. Sci."},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1111\/vco.12106","article-title":"A comparison of clinical, magnetic resonance imaging and pathological findings in dogs with gliomatosis cerebri, focusing on cases with minimal magnetic resonance imaging changes","volume":"14","author":"Bentley","year":"2016","journal-title":"Vet. Comp. Oncol."},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/j.tvjl.2013.08.015","article-title":"Canine intracranial gliomas: Relationship between magnetic resonance imaging criteria and tumor type and grade","volume":"198","author":"Bentley","year":"2013","journal-title":"Vet. J."},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1111\/j.1740-8261.2010.01758.x","article-title":"Magnetic resonance imaging features of intracranial astrocytomas and oligodendrogliomas in dogs","volume":"52","author":"Young","year":"2011","journal-title":"Vet. Radiol. Ultrasound"},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1111\/j.1748-5827.2011.01053.x","article-title":"Non-enhancing confirmed oligodendroglioma in three dogs","volume":"52","author":"Motta","year":"2011","journal-title":"J. Small. Anim. Pract."},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1354\/vp.40-6-659","article-title":"Glioblastoma multiforme: Clinical findings, magnetic resonance imaging, and pathology in five dogs","volume":"40","author":"Lipsitz","year":"2003","journal-title":"Vet. Pathol."},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1111\/j.1939-1676.2008.0170.x","article-title":"Choroid plexus tumors in 56 dogs (1985\u20132007)","volume":"22","author":"Westworth","year":"2008","journal-title":"J. Vet. Intern. Med."},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1111\/vru.13041","article-title":"MRI features of canine hemangiosarcoma affecting the central nervous system","volume":"63","author":"Mallol","year":"2022","journal-title":"Vet. Radiol. Ultrasound"},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1111\/vru.12254","article-title":"CT and MRI features of carotid body paragangliomas in 16 dogs","volume":"56","author":"Mai","year":"2015","journal-title":"Vet. Radiol. Ultrasound"},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1148\/radiol.2413051276","article-title":"Malignant astrocytic tumors: Clinical importance of apparent diffusion coefficient in prediction of grade and prognosis","volume":"241","author":"Higano","year":"2006","journal-title":"Radiology"},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.rcl.2016.09.002","article-title":"Imaging of the sella and parasellar region","volume":"55","author":"Go","year":"2017","journal-title":"Radiol. Clin. N. Am."},{"key":"ref_86","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1111\/vru.12938","article-title":"Variation in the MRI appearance of the canine pituitary gland","volume":"62","author":"Travetti","year":"2021","journal-title":"Vet. Radiol. Ultrasound"},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1177\/0300985816658101","article-title":"Canine nervous system lymphoma subtypes display characteristic neuroanatomical patterns","volume":"54","author":"Moore","year":"2017","journal-title":"Vet. Pathol."},{"key":"ref_88","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1111\/jvim.16654","article-title":"Quantitative analysis of magnetic resonance images for characterization of blood-brain barrier dysfunction in dogs with brain tumors","volume":"37","author":"Hanael","year":"2023","journal-title":"J. Vet. Int. Med."},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1111\/vco.12853","article-title":"Inter-pathologist agreement on diagnosis, classification and grading of canine glioma","volume":"20","author":"Krane","year":"2022","journal-title":"Vet. Comp. Oncol."},{"key":"ref_90","unstructured":"(2024, February 06). The Cancer Imaging Archive, Cancer Imaging Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Available online: https:\/\/imaging.cancer.gov\/informatics\/cancer_imaging_archive.htm."}],"container-title":["Animals"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2076-2615\/14\/7\/1044\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T14:20:53Z","timestamp":1760106053000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2076-2615\/14\/7\/1044"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,29]]},"references-count":90,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2024,4]]}},"alternative-id":["ani14071044"],"URL":"https:\/\/doi.org\/10.3390\/ani14071044","relation":{},"ISSN":["2076-2615"],"issn-type":[{"value":"2076-2615","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3,29]]}}}