{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T16:19:30Z","timestamp":1785773970014,"version":"3.56.0"},"reference-count":50,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2024,3,29]],"date-time":"2024-03-29T00:00:00Z","timestamp":1711670400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Major Scientific and Technology Special Project","award":["221100110200"],"award-info":[{"award-number":["221100110200"]}]},{"name":"Major Scientific and Technology Special Project","award":["CX(22)3042"],"award-info":[{"award-number":["CX(22)3042"]}]},{"name":"Agricultural Science and Technology Independent Innovation Fund of Jiangsu Province","award":["221100110200"],"award-info":[{"award-number":["221100110200"]}]},{"name":"Agricultural Science and Technology Independent Innovation Fund of Jiangsu Province","award":["CX(22)3042"],"award-info":[{"award-number":["CX(22)3042"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animals"],"abstract":"<jats:p>The Taihu Dianzi pigeon is a breed native to China, and its special piebalding, crest, and polydactyly phenotypes are the result of artificial and natural selection. Here, we analyzed the genetic differences among three kinds of pigeons with different phenotypes at the genomic level. A selective sweep was conducted based on the fixation index (FST) and nucleotide diversity (\u03c0) ratio, and the results revealed that MC1R was related to the formation of the distinctive piebalding of the Taihu Dianzi pigeon. Combined with the results of genome-wide association studies, we identified candidate genes associated with the crest (SMYD and STOX2) and polydactyly (SLC52A3 and ANGPT4). The candidate genes identified in this study and their variants may be useful for understanding the genetic mechanism underlying the special phenotypes of the Taihu Dianzi pigeon. This study provides new insights into the genetic factors that may influence the formation of the special piebalding, crest, and polydactyly characteristics in pigeons.<\/jats:p>","DOI":"10.3390\/ani14071047","type":"journal-article","created":{"date-parts":[[2024,3,31]],"date-time":"2024-03-31T13:28:00Z","timestamp":1711891680000},"page":"1047","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Whole-Genome Sequencing for Identifying Candidate Genes Related to the Special Phenotypes of the Taihu Dianzi Pigeon"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-8719-6049","authenticated-orcid":false,"given":"Rui","family":"Zhang","sequence":"first","affiliation":[{"name":"Institute of Poultry Science, Chinese Academy of Agricultural Sciences Poultry Institute, Yangzhou 225100, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunyu","family":"Mu","sequence":"additional","affiliation":[{"name":"Institute of Poultry Science, Chinese Academy of Agricultural Sciences Poultry Institute, Yangzhou 225100, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingling","family":"Chang","sequence":"additional","affiliation":[{"name":"Institute of Poultry Science, Chinese Academy of Agricultural Sciences Poultry Institute, Yangzhou 225100, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyue","family":"Shen","sequence":"additional","affiliation":[{"name":"Institute of Poultry Science, Chinese Academy of Agricultural Sciences Poultry Institute, Yangzhou 225100, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhu","family":"Bu","sequence":"additional","affiliation":[{"name":"Institute of Poultry Science, Chinese Academy of Agricultural Sciences Poultry Institute, Yangzhou 225100, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingjun","family":"Yang","sequence":"additional","affiliation":[{"name":"Henan Tiancheng Pigeon Industry Co., Ltd., Pingdingshan 462513, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shengyong","family":"Fu","sequence":"additional","affiliation":[{"name":"Institute of Poultry Science, Chinese Academy of Agricultural Sciences Poultry Institute, Yangzhou 225100, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingping","family":"Tang","sequence":"additional","affiliation":[{"name":"Institute of Poultry Science, Chinese Academy of Agricultural Sciences Poultry Institute, Yangzhou 225100, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peiyao","family":"Liu","sequence":"additional","affiliation":[{"name":"Henan Tiancheng Pigeon Industry Co., Ltd., Pingdingshan 462513, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoming","family":"Yang","sequence":"additional","affiliation":[{"name":"Henan Tiancheng Pigeon Industry Co., Ltd., Pingdingshan 462513, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,3,29]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/j.cub.2011.12.045","article-title":"Divergence, convergence, and the ancestry of feral populations in the domestic rock pigeon","volume":"22","author":"Stringham","year":"2012","journal-title":"Curr. 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