{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T04:37:08Z","timestamp":1788583028177,"version":"build-2803163510"},"reference-count":45,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2024,5,16]],"date-time":"2024-05-16T00:00:00Z","timestamp":1715817600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["42171060"],"award-info":[{"award-number":["42171060"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["2021DB014"],"award-info":[{"award-number":["2021DB014"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["CARS-38"],"award-info":[{"award-number":["CARS-38"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Innovation and Development Supporting Plan Project of Key Industries in Southern Xinjiang","award":["42171060"],"award-info":[{"award-number":["42171060"]}]},{"name":"Innovation and Development Supporting Plan Project of Key Industries in Southern Xinjiang","award":["2021DB014"],"award-info":[{"award-number":["2021DB014"]}]},{"name":"Innovation and Development Supporting Plan Project of Key Industries in Southern Xinjiang","award":["CARS-38"],"award-info":[{"award-number":["CARS-38"]}]},{"name":"National Meat Sheep Industry Technical System Post Scientist Project","award":["42171060"],"award-info":[{"award-number":["42171060"]}]},{"name":"National Meat Sheep Industry Technical System Post Scientist Project","award":["2021DB014"],"award-info":[{"award-number":["2021DB014"]}]},{"name":"National Meat Sheep Industry Technical System Post Scientist Project","award":["CARS-38"],"award-info":[{"award-number":["CARS-38"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animals"],"abstract":"<jats:p>Due to the degradation of pasture and strict restrictions on grazing ranges in recent years, copper (Cu) deficiency in Yudong black goats has been occurring, mainly manifested as emaciation, anemia, loss of appetite and lack of spirit. To explore the main causes of Cu deficiency in Yudong black goats, 40 black goats (1 year old, 25.11 \u00b1 0.52 kg) were selected for this experiment; among them, 20 Yudong black goats with Cu deficiency from the experimental pasture were used as the experimental group, and 20 healthy Yudong black goats from the control pasture were used as the control group. In the pre-experiment, the mineral contents of the soil, forage, blood, and liver of black goats in both groups were determined, and in formal experiments, blood hematological, biochemical, antioxidant, and hemorheological parameters were analyzed. An experiment on the treatment of Cu deficiency in black goats was also conducted. This study showed that selenium (Se) levels in the soil, forage, blood, and liver from the experimental group were significantly lower than those from the control group (p &lt; 0.01). The content of sulfur (S) in the forage was considerably higher than that of the control group (p &lt; 0.01). The contents of Cu in the blood and liver from the experimental group were significantly lower than that from the control group (p &lt; 0.01), and the content of S was considerably higher than that from the control group (p &lt; 0.01). The blood hematology of the experimental group was affected, as evidenced by a decrease in hemoglobin, hematocrit value, mean corpuscular volume and mean corpuscular hemoglobin. The immunity and antioxidant capacity of black goats in the experiment group were impaired to varying degrees, with significant decreases in ceruloplasmin, immunoglobulin M, immunoglobulin G, glutathione peroxidase, and superoxide dismutase, and substantial increases in malondialdehyde. In addition, the experimental group showed a decrease in blood viscosity as evidenced by the rise in high shear viscosity, low shear viscosity, erythrocyte rigidity index, erythrocyte aggregation index, and erythrocyte deformation index, and a decrease in plasma viscosity. In the treatment experiment, oral administration of copper sulfate solution was carried out on 10 black goats with Cu deficiency. All the Cu deficiency goats were cured, and the Cu content in their bodies rebounded. In summary, low Se soil caused an increase in S content in the forage, and Yudong black goats feeding on high S forage resulted in a decrease in Cu absorption, which led to a secondary Cu deficiency.<\/jats:p>","DOI":"10.3390\/ani14101481","type":"journal-article","created":{"date-parts":[[2024,5,16]],"date-time":"2024-05-16T09:30:03Z","timestamp":1715851803000},"page":"1481","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Study on Soil Selenium-Induced Copper Deficiency in Yudong Black Goats"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-9900-3237","authenticated-orcid":false,"given":"Guangyang","family":"Liu","sequence":"first","affiliation":[{"name":"School of Life Science and Engineering, Southwest University of Science and Technology, Mianyang 621010, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1515-1648","authenticated-orcid":false,"given":"Xiaoyun","family":"Shen","sequence":"additional","affiliation":[{"name":"School of Life Science and Engineering, Southwest University of Science and Technology, Mianyang 621010, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,5,16]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Yang, S.J., Zhang, X.Y., Li, X.C., Zheng, J.K., Zhao, L., Fan, C.L., and Zhao, Y.J. 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