{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T13:41:23Z","timestamp":1787233283955,"version":"build-2736575974"},"reference-count":48,"publisher":"MDPI AG","issue":"16","license":[{"start":{"date-parts":[[2024,8,17]],"date-time":"2024-08-17T00:00:00Z","timestamp":1723852800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"European Investment Funds Interreg VA Flanders","award":["LLP22"],"award-info":[{"award-number":["LLP22"]}]},{"name":"European Investment Funds Interreg VA Flanders","award":["LLP12"],"award-info":[{"award-number":["LLP12"]}]},{"name":"Ministry of Economic Affairs (NL)","award":["LLP22"],"award-info":[{"award-number":["LLP22"]}]},{"name":"Ministry of Economic Affairs (NL)","award":["LLP12"],"award-info":[{"award-number":["LLP12"]}]},{"name":"Provinces of Limburg (NL)","award":["LLP22"],"award-info":[{"award-number":["LLP22"]}]},{"name":"Provinces of Limburg (NL)","award":["LLP12"],"award-info":[{"award-number":["LLP12"]}]},{"name":"Flemish-Brabant (B)","award":["LLP22"],"award-info":[{"award-number":["LLP22"]}]},{"name":"Flemish-Brabant (B)","award":["LLP12"],"award-info":[{"award-number":["LLP12"]}]},{"name":"Friends of VetMed (Vrienden Diergeneeskunde)","award":["LLP22"],"award-info":[{"award-number":["LLP22"]}]},{"name":"Friends of VetMed (Vrienden Diergeneeskunde)","award":["LLP12"],"award-info":[{"award-number":["LLP12"]}]},{"name":"Dutch Arthritis Society","award":["LLP22"],"award-info":[{"award-number":["LLP22"]}]},{"name":"Dutch Arthritis Society","award":["LLP12"],"award-info":[{"award-number":["LLP12"]}]},{"name":"EPOS-NL Research Infrastructure program","award":["LLP22"],"award-info":[{"award-number":["LLP22"]}]},{"name":"EPOS-NL Research Infrastructure program","award":["LLP12"],"award-info":[{"award-number":["LLP12"]}]},{"name":"Faculty of Veterinary Medicine, Kasetsart University, Thailand","award":["LLP22"],"award-info":[{"award-number":["LLP22"]}]},{"name":"Faculty of Veterinary Medicine, Kasetsart University, Thailand","award":["LLP12"],"award-info":[{"award-number":["LLP12"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animals"],"abstract":"<jats:p>The acetabular rim extension (ACE-X) implant is a custom-made three-dimensionally printed titanium device designed for the treatment of canine hip dysplasia. In this study, 34 dogs (61 hips) underwent ACE-X implantation, and assessments were conducted using computed tomography, force plate analysis, Ortolani\u2019s test, and the Helsinki chronic pain index (HCPI) questionnaires at five intervals: the pre-operative day, the surgery day, and the 1.5-month, 3-month, and 12-month follow-ups. Statistically significant increases in femoral head coverage with a negative Ortolani subluxation test were observed immediately after surgery and persisted throughout the study. Osteoarthritis (OA) scores remained stable, but osteophyte size significantly increased between the surgery day and the 12-month follow-up, especially in hips with a baseline OA score of 2 compared to those with a score of 1. The force plate data showed no significant changes during the study. The HCPI demonstrated a significant decrease in pain score from pre-operative value to six-week follow-up and gradually decreased over time. Major complications were identified in six hips (9.8%) of four dogs. In conclusion, the ACE-X implant effectively increased femoral head coverage, eliminated subluxation, and provided long-term pain relief with minimal complications, benefiting over 90% of the study population. The study supports the ACE-X implant as a valuable alternative treatment for canine hip dysplasia.<\/jats:p>","DOI":"10.3390\/ani14162385","type":"journal-article","created":{"date-parts":[[2024,8,19]],"date-time":"2024-08-19T05:19:36Z","timestamp":1724044776000},"page":"2385","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Outcome One Year after Acetabular Rim Extension Using a Customized Titanium Implant for Treating Hip Dysplasia in Dogs"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-7162-9842","authenticated-orcid":false,"given":"Irin","family":"Kwananocha","sequence":"first","affiliation":[{"name":"Department of Clinical Sciences, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 1, 3584 CL Utrecht, The Netherlands"},{"name":"Research and Academic Service, Faculty of Veterinary Medicine, Kasetsart University, 50 Ngamwongwan Rd., Lat Yao, Chatuchak, Bangkok 10900, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1689-5104","authenticated-orcid":false,"given":"Jo\u00ebll","family":"Magr\u00e9","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands"},{"name":"3D Lab UMC Utrecht, Division of Surgical Specialties, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amir","family":"Kamali","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 1, 3584 CL Utrecht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Femke","family":"Verseijden","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 1, 3584 CL Utrecht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koen","family":"Willemsen","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands"},{"name":"3D Lab UMC Utrecht, Division of Surgical Specialties, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuntao","family":"Ji","sequence":"additional","affiliation":[{"name":"Department of Earth Sciences, Faculty of Geosciences, Utrecht University, Princetonlaan 8a, 3584 CB Utrecht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bart C. H.","family":"van der Wal","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ralph J. B.","family":"Sakkers","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2333-7162","authenticated-orcid":false,"given":"Marianna A.","family":"Tryfonidou","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 1, 3584 CL Utrecht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0165-1169","authenticated-orcid":false,"given":"Bj\u00f6rn P.","family":"Meij","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 1, 3584 CL Utrecht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,8,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"5723476","DOI":"10.1155\/2017\/5723476","article-title":"The Demographics of Canine Hip Dysplasia in the United States and Canada","volume":"2017","author":"Loder","year":"2017","journal-title":"J. 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