{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T02:38:36Z","timestamp":1789094316207,"version":"build-2803163510"},"reference-count":33,"publisher":"MDPI AG","issue":"18","license":[{"start":{"date-parts":[[2024,9,11]],"date-time":"2024-09-11T00:00:00Z","timestamp":1726012800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animals"],"abstract":"<jats:p>The complete blood cell count (CBC) was screened in a group of 15 donkeys, of which 8 were of Asinara breed (oculocutaneous albinism type 1, OCA1) and 7 of Sardo breed (gray coat). All donkeys were kept under same management and dietary conditions and underwent periodic health monitoring in the month of June 2024, at the peak of the positive photoperiod, at Mediterranean latitudes. One aliquot of whole blood, drawn from each individual into K2-EDTA containing tubes, was analyzed for the complete blood cell count through an automatic analyzer, within two hours of sampling. Data were analyzed and compared by one-way ANOVA, where the breed was an independent variable. All animals appeared clinically healthy, though mild eosinophilia was observed in Sardo donkeys. The red blood cell line showed peculiar traits for Asinara donkeys, which displayed significantly higher circulating red blood cell numbers than gray coat Sardo donkeys (RBC, 5.19 vs. 3.80 1012\/mL \u00b1 0.98 pooled-St. Dev, respectively; p = 0.017). RBCs also exhibited a smaller diameter and higher degree of anisocytosis in Asinara donkeys, along with lower hematocrit value, albeit within physiological ranges. Taken all together, such hematological profile depicts a peculiar trait of the red blood cell line in albino donkeys during the positive photoperiod.<\/jats:p>","DOI":"10.3390\/ani14182641","type":"journal-article","created":{"date-parts":[[2024,9,11]],"date-time":"2024-09-11T10:33:01Z","timestamp":1726050781000},"page":"2641","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Albinism and Blood Cell Profile: The Peculiar Case of Asinara Donkeys"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8863-9834","authenticated-orcid":false,"given":"Maria Grazia","family":"Cappai","sequence":"first","affiliation":[{"name":"Nutrition Desk of the Veterinary Teaching Hospital, University of Sassari, 07100 Sassari, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3159-7279","authenticated-orcid":false,"given":"Alice","family":"Senes","sequence":"additional","affiliation":[{"name":"Nutrition Desk of the Veterinary Teaching Hospital, University of Sassari, 07100 Sassari, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovannantonio","family":"Pilo","sequence":"additional","affiliation":[{"name":"Istituto Zooprofilattico Sperimentale della Sardegna \u201cG. Pegreffi\u201d, 07100 Sassari, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,9,11]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"502","DOI":"10.4081\/ijas.2015.3976","article-title":"Cutaneous metabolic pathway of tyrosine as a precursor to melanin in Asinara white donkey, Equus asinus L., 1758","volume":"14","author":"Cappai","year":"2015","journal-title":"Ital. J. Anim. Sci."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1186\/1750-1172-2-43","article-title":"Oculocutaneous albinism","volume":"2","author":"Ek","year":"2007","journal-title":"Orphanet J. 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