{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T22:23:55Z","timestamp":1788992635698,"version":"build-2803163510"},"reference-count":104,"publisher":"MDPI AG","issue":"19","license":[{"start":{"date-parts":[[2024,9,25]],"date-time":"2024-09-25T00:00:00Z","timestamp":1727222400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animals"],"abstract":"<jats:p>The aims of the present meta-analysis were (i) to re-evaluate the factorially calculated Ca, P and Mg requirements to replace endogenous faecal losses, taking new data into account, (ii) to identify potential differences between horses and ponies regarding requirements, apparent digestibility, serum levels and renal excretion of Ca, P and Mg and (iii) to investigate the influence of mineral sources, i.e., \u201cinorganic\u201d sources from added mineral salts and \u201corganic\u201d sources from feed plants. For P, the water solubility of \u201cinorganic\u201d sources was taken into consideration. Data on the aforementioned parameters from 42 studies were plotted against intake, similar to the Lucas test for true digestibility and faecal endogenous losses. Within specific intake ranges, data were compared using t-tests and an ANOVA, followed by Holm\u2013Sidak post hoc tests. Ponies had lower endogenous faecal Mg losses than horses. Consequently, apparent Mg digestibility was higher in ponies. Factorial calculations of Mg requirements to replace faecal losses showed that ponies needed approximately half of the current recommended amount, while horses required 1.9 times the amount currently recommended by Kienzle and Burger. The overall mean matched previous recommendations. For Ca, there was no discernible difference between ponies and horses. True Ca digestibility calculated by the Lucas test was higher and endogenous losses were lower when \u201corganic\u201d Ca was fed as opposed to when \u201cinorganic\u201d sources were used. The resulting factorial calculations of the requirements to replace faecal losses were close to current recommendations for \u201corganic\u201d Ca. For \u201cinorganic\u201d sources, however, the new calculations were below the recommended level. For P, there were no discernible differences between horses and ponies. There were also no clear effects of \u201cinorganic\u201d or \u201corganic\u201d P sources. The water solubility of \u201cinorganic\u201d sources was the key factor determining P metabolism. Water-soluble P sources exhibited higher true and apparent digestibility. The intake of these P sources led to hyperphosphatemia and hyperphosphaturia, even at low intakes. In other species, this has been shown to pose a health risk. Therefore, it is recommended to avoid the use of highly water-soluble \u201cinorganic\u201d P sources in horses and ponies. Given the lower digestibility of insoluble P sources, the factorially calculated P requirements for such sources are higher than the current recommendations.<\/jats:p>","DOI":"10.3390\/ani14192765","type":"journal-article","created":{"date-parts":[[2024,9,25]],"date-time":"2024-09-25T04:01:24Z","timestamp":1727236884000},"page":"2765","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["A Meta-Analysis on Quantitative Calcium, Phosphorus and Magnesium Metabolism in Horses and Ponies"],"prefix":"10.3390","volume":"14","author":[{"given":"Isabelle","family":"Maier","sequence":"first","affiliation":[{"name":"Department of Veterinary Sciences, Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen, Schoenleutnerstr. 8, D-85764 Oberschleissheim, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ellen","family":"Kienzle","sequence":"additional","affiliation":[{"name":"Department of Veterinary Sciences, Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen, Schoenleutnerstr. 8, D-85764 Oberschleissheim, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,9,25]]},"reference":[{"key":"ref_1","unstructured":"Burger, A. 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