{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T05:44:46Z","timestamp":1771479886001,"version":"3.50.1"},"reference-count":127,"publisher":"MDPI AG","issue":"21","license":[{"start":{"date-parts":[[2024,10,24]],"date-time":"2024-10-24T00:00:00Z","timestamp":1729728000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Pathway Intermediates Inc. (Seoul, Republic of Korea)","award":["98\/128"],"award-info":[{"award-number":["98\/128"]}]},{"name":"Pathway Intermediates Inc. (Seoul, Republic of Korea)","award":["9908234"],"award-info":[{"award-number":["9908234"]}]},{"DOI":"10.13039\/501100007864","name":"Isfahan University of Technology","doi-asserted-by":"publisher","award":["98\/128"],"award-info":[{"award-number":["98\/128"]}],"id":[{"id":"10.13039\/501100007864","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007864","name":"Isfahan University of Technology","doi-asserted-by":"publisher","award":["9908234"],"award-info":[{"award-number":["9908234"]}],"id":[{"id":"10.13039\/501100007864","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animals"],"abstract":"<jats:p>The present study aimed to investigate whether supplementation of modified lysophospholipids (LPLs) in the diet of broiler breeders can benefit their offspring. A total of 264 49-week-old breeders (Ross 308) were allocated and fed based on a 2 \u00d7 2 factorial arrangement with two levels of dietary energy (normal energy = 2800 kcal\/kg and low energy = 2760 kcal\/kg) and two LPL levels (0 and 0.5 g\/kg) for periods of 8 and 12 weeks. The offspring were assessed for growth performance, serum parameters, hepatic antioxidative capability, and expression of genes involved in liver \u03b2-oxidation at 7 days old. The LPL inclusion improved (p &lt; 0.01) average body weight (ABW), average daily gain (ADG), and feed conversion ratio (FCR). The offspring of 61-week-old breeders fed with LPL exhibited reduced serum triglyceride levels (p &lt; 0.01) but an increase in hepatic glutathione peroxidase (p &lt; 0.05). The LPL increased (p &lt; 0.001) the mRNA expression of the PGC-1\u03b1 gene in the liver. Supplementing LPL in low-energy diets resulted in higher FABP1 gene expression (p &lt; 0.05) in the intestine. In conclusion, LPL supplementation in the breeders\u2019 diet improved offspring performance by enhancing fatty acid absorption, hepatic indices, and the expression of genes involved in liver \u03b2-oxidation.<\/jats:p>","DOI":"10.3390\/ani14213066","type":"journal-article","created":{"date-parts":[[2024,10,24]],"date-time":"2024-10-24T09:11:47Z","timestamp":1729761107000},"page":"3066","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Lysophospholipid Supplementation in Broiler Breeders\u2019 Diet Benefits Offspring\u2019s Productive Performance, Blood Parameters, and Hepatic \u03b2-Oxidation Genes"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8190-9803","authenticated-orcid":false,"given":"Mohammad","family":"Sedghi","sequence":"first","affiliation":[{"name":"Department of Animal Sciences, College of Agriculture, Isfahan University of Technology, Isfahan 84156-83111, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatemeh","family":"Javanmard","sequence":"additional","affiliation":[{"name":"Department of Animal Sciences, College of Agriculture, Isfahan University of Technology, Isfahan 84156-83111, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anvar","family":"Amoozmehr","sequence":"additional","affiliation":[{"name":"Department of Animal and Poultry Nutrition, Faculty of Animal Science, Gorgan University of Agricultural Sciences and Natural Resources, Shahid Beheshti Ave, Gorgan 49138-15739, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7973-3455","authenticated-orcid":false,"given":"Saeid","family":"Zamany","sequence":"additional","affiliation":[{"name":"Department of Animal Sciences, College of Agriculture, Isfahan University of Technology, Isfahan 84156-83111, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ishmael","family":"Mohammadi","sequence":"additional","affiliation":[{"name":"Department of Animal Sciences, College of Agriculture, Isfahan University of Technology, Isfahan 84156-83111, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0005-352X","authenticated-orcid":false,"given":"Woo","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Poultry Science, University of Georgia, Athens, GA 30602, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Venkata Sesha Reddy","family":"Choppa","sequence":"additional","affiliation":[{"name":"Department of Poultry Science, University of Georgia, Athens, GA 30602, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,10,24]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"9214209","DOI":"10.1155\/2019\/9214209","article-title":"Supplementing Genistein for Breeder Hens Alters the Fatty Acid Metabolism and Growth Performance of Offsprings by Epigenetic Modification","volume":"2019","author":"Lv","year":"2019","journal-title":"Oxid. Med. Cell Longev."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.jnutbio.2014.10.001","article-title":"Type of Fatty Acids in Maternal Diets during Pregnancy and\/or Lactation and Metabolic Consequences of the Offspring","volume":"26","author":"Mennitti","year":"2015","journal-title":"J. Nutr. Biochem."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1080\/00071668.2020.1847254","article-title":"Impact of Feeding N-3 Fatty Acids to Layer Breeders and Their Offspring on Concentration of Antibody Titres against Infectious Bronchitis, and Newcastle Diseases and Plasma Fatty Acids in the Offspring","volume":"62","author":"Ma","year":"2021","journal-title":"Br. Poult. Sci."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"43","DOI":"10.3382\/ps\/peu006","article-title":"Transition of Maternal Dietary N-3 Fatty Acids from the Yolk to the Liver of Broiler Breeder Progeny via the Residual Yolk Sac","volume":"94","author":"Koppenol","year":"2015","journal-title":"Poult. Sci."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"564","DOI":"10.3382\/ps.2013-03320","article-title":"Effect of the Ratio of Dietary N-3 Fatty Acids Eicosapentaenoic Acid and Docosahexaenoic Acid on Broiler Breeder Performance, Egg Quality, and Yolk Fatty Acid Composition at Different Breeder Ages","volume":"93","author":"Koppenol","year":"2014","journal-title":"Poult. Sci."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1093\/ps\/86.5.1012","article-title":"Metabolic and Cardiovascular Diseases in Poultry: Role of Dietary Lipids","volume":"86","author":"Cherian","year":"2007","journal-title":"Poult. Sci."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.cis.2010.12.002","article-title":"The Role of Bile Salts in Digestion","volume":"165","author":"Wilde","year":"2011","journal-title":"Adv. Colloid Interface Sci."},{"key":"ref_8","doi-asserted-by":"crossref","unstructured":"Krezhova, D. (2012). Recent Trends for Enhancing the Diversity and Quality of Soybean Products, InTech.","DOI":"10.5772\/1005"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"2506","DOI":"10.3382\/ps\/pev181","article-title":"Interaction between Fat Type and Lysolecithin Supplementation in Broiler Feeds","volume":"94","author":"Jansen","year":"2015","journal-title":"Poult. Sci."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1017\/S0043933917000502","article-title":"Emulsifiers in the Poultry Industry","volume":"73","author":"Siyal","year":"2017","journal-title":"Worlds. Poult. Sci. J."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"10128","DOI":"10.1074\/jbc.275.14.10128","article-title":"Lysophospholipids Open the Two-Pore Domain Mechano-Gated K+ Channels TREK-1 and TRAAK","volume":"275","author":"Maingret","year":"2000","journal-title":"J. Biol. Chem."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"2011","DOI":"10.1016\/j.bbamem.2007.05.011","article-title":"The Gramicidin Ion Channel: A Model Membrane Protein","volume":"1768","author":"Kelkar","year":"2007","journal-title":"Biochim. Biophys. Acta Biomembr."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1098\/rsif.2009.0443","article-title":"Lipid Bilayer Regulation of Membrane Protein Function: Gramicidin Channels as Molecular Force Probes","volume":"7","author":"Collingwood","year":"2010","journal-title":"J. R. Soc. Interface"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.plipres.2012.09.002","article-title":"Membrane-Perturbing Effect of Fatty Acids and Lysolipids","volume":"52","author":"Arouri","year":"2013","journal-title":"Prog. Lipid Res."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"3902","DOI":"10.3382\/ps\/pez111","article-title":"Effects of Lysophospholipid on Growth Performance, Carcass Yield, Intestinal Development, and Bone Quality in Broilers","volume":"98","author":"Chen","year":"2019","journal-title":"Poult. Sci."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"6693","DOI":"10.3382\/ps\/pex005","article-title":"Effects of Lysophospholipid Supplementation to Reduced Energy, Crude Protein, and Amino Acid Diets on Growth Performance, Nutrient Digestibility, and Blood Profiles in Broiler Chickens","volume":"98","author":"Boontiam","year":"2019","journal-title":"Poult. Sci."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"2516","DOI":"10.1096\/fj.09-144436","article-title":"Postprandial Lysophospholipid Suppresses Hepatic Fatty Acid Oxidation: The Molecular Link between Group 1B Phospholipase A 2 and Diet-induced Obesity","volume":"24","author":"Pfluger","year":"2010","journal-title":"FASEB J."},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"Cheng, C.F., Ku, H.C., and Lin, H. (2018). Pgc-1\u03b1 as a Pivotal Factor in Lipid and Metabolic Regulation. Int. J. Mol. Sci., 19.","DOI":"10.3390\/ijms19113447"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/S0167-7306(02)36022-8","article-title":"Dynamics of Lipoprotein Transport in the Human Circulatory System","volume":"Volume 36","author":"Fielding","year":"2002","journal-title":"New Comprehensive Biochemistry"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1016\/B978-0-12-809954-4.00048-7","article-title":"Enterocyte Fatty Acid Handling Proteins and Chylomicron Formation","volume":"Volume 2","author":"Cifarelli","year":"2018","journal-title":"Physiology of the Gastrointestinal Tract"},{"key":"ref_21","doi-asserted-by":"crossref","unstructured":"Wang, M., Wang, K., Liao, X., Hu, H., Chen, L., Meng, L., Gao, W., and Li, Q. (2021). Carnitine Palmitoyltransferase System: A New Target for Anti-Inflammatory and Anticancer Therapy?. Front. Pharmacol., 12.","DOI":"10.3389\/fphar.2021.760581"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"220","DOI":"10.2141\/jpsa.009123","article-title":"Effects of Dietary Protein Levels on Amino Acid Digestibility at Different Sites of Male Adult Chicken Intestines","volume":"47","author":"Kamisoyama","year":"2010","journal-title":"J. Poult. Sci."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1080\/00071668.2011.640929","article-title":"Rice Bran Lysolecithin as a Source of Energy in Broiler Chicken Diet","volume":"52","author":"Raju","year":"2011","journal-title":"Br. Poult. Sci."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.anifeedsci.2010.10.004","article-title":"Effect of Fat Type and Lysophosphatidylcholine Addition to Broiler Diets on Performance, Apparent Digestibility of Fatty Acids, and Apparent Metabolizable Energy Content","volume":"163","author":"Zhang","year":"2011","journal-title":"Anim. Feed Sci. Technol."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.3382\/ps\/pew469","article-title":"Effect of Diets with Different Energy and Lysophospholipids Levels on Performance, Nutrient Metabolism, and Body Composition in Broilers","volume":"96","author":"Zhao","year":"2017","journal-title":"Poult. Sci."},{"key":"ref_26","first-page":"316","article-title":"Influence of Dietary Supplementation of Phospholipids and Lysophospholipids on Performance of Broilers","volume":"28","author":"Malapure","year":"2011","journal-title":"Indian J. Anim. Nutr."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.livsci.2015.03.011","article-title":"Influence of Dietary Fat Sources and Lysolecithin on Growth Performance, Visceral Organ Size, and Histological Intestinal Alteration in Broiler Chickens","volume":"176","author":"Khonyoung","year":"2015","journal-title":"Livest. Sci."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1080\/1828051X.2016.1192965","article-title":"Effect of Dietary Supplementation of Lysophospholipids on Productive Performance, Nutrient Digestibility and Carcass Quality Traits of Broiler Chickens","volume":"15","author":"Zampiga","year":"2016","journal-title":"Ital. J. Anim. Sci."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1080\/00071668.2016.1219019","article-title":"Effects of Lipid Sources, Lysophospholipids and Organic Acids in Maize-Based Broiler Diets on Nutrient Balance, Liver Concentration of Fat-Soluble Vitamins, Jejunal Microbiota and Performance","volume":"57","author":"Polycarpo","year":"2016","journal-title":"Br. Poult. Sci."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1080\/00071668.2018.1423676","article-title":"Effects of Lysolecithin Supplementation in Low-Energy Diets on Growth Performance, Nutrient Digestibility, Viscosity and Intestinal Morphology of Broilers","volume":"59","author":"Papadopoulos","year":"2018","journal-title":"Br. Poult. Sci."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.3892\/or.2020.7661","article-title":"TGF-\u03921-Induced Epithelial-Mesenchymal Transition Increases Fatty Acid Oxidation and OXPHOS Activity via the p-AMPK Pathway in Breast Cancer Cells","volume":"44","author":"Liu","year":"2020","journal-title":"Oncol. Rep."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"1444","DOI":"10.1093\/ps\/80.10.1444","article-title":"Effects of Incubator Humidity and Hen Age on Yolk Composition in Broiler Hatching Eggs from Young Breeders","volume":"80","author":"Burnham","year":"2001","journal-title":"Poult. Sci."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.domaniend.2019.01.007","article-title":"Effects of Nutrition Restriction of Fat- and Lean-Line Broiler Breeder Hens during the Laying Period on Offspring Performance, Blood Biochemical Parameters, and Hormone Levels","volume":"68","author":"Li","year":"2019","journal-title":"Domest. Anim. Endocrinol."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/0377-8401(95)00931-0","article-title":"Utilization of Different Fats and Oils by Adult Chickens as a Source of Energy, Lipid and Fatty Acids","volume":"61","author":"Blanch","year":"1996","journal-title":"Anim. Feed Sci. Technol."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1017\/S0021859698005851","article-title":"Influence of Dietary Energy and Nutrient Concentration on the Growth of Body Weight and of Carcass Components of Broiler Chickens","volume":"131","author":"Wiseman","year":"1998","journal-title":"J. Agric. Sci."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1038\/s41684-021-00871-3","article-title":"Guideline for the Care and Use of Laboratory Animals in Iran","volume":"50","author":"Sadighi","year":"2021","journal-title":"Lab Anim."},{"key":"ref_37","unstructured":"Aviagen (2020). Ross 308. Parent Stock Handbook, Aviagen."},{"key":"ref_38","unstructured":"Aviagen (2020). Ross 308. Broiler Management Guide, Aviagen."},{"key":"ref_39","unstructured":"Aviagen (2020). Ross 308. Nutrition Specifications, Aviagen."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"87","DOI":"10.4103\/0976-500X.72350","article-title":"Blood Sample Collection in Small Laboratory Animals","volume":"1","author":"Parasuraman","year":"2010","journal-title":"J. Pharmacol. Pharmacother."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"807","DOI":"10.3923\/ijps.2011.807.813","article-title":"Effect of Dietary Zinc on Certain Blood Traits of Broiler Breeder Chickens","volume":"10","author":"Amen","year":"2011","journal-title":"Int. J. Poult. Sci."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.aninu.2021.06.018","article-title":"Metabolic Utilization of Intravenously Injected Iron from Different Iron Sources in Target Tissues of Broiler Chickens","volume":"9","author":"Lu","year":"2022","journal-title":"Anim. Nutr."},{"key":"ref_43","doi-asserted-by":"crossref","unstructured":"Snyder, A.M., Riley, S.P., Robison, C.I., Karcher, D.M., Wickware, C.L., Johnson, T.A., and Weimer, S.L. (2022). Behavior and Immune Response of Conventional and Slow-Growing Broilers to Salmonella Typhimurium. Front. Physiol., 13.","DOI":"10.3389\/fphys.2022.890848"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"144394","DOI":"10.1016\/j.gene.2020.144394","article-title":"Positive Effects of Conjugated Linoleic Acid (CLA) on the PGC1-\u03b1 Expression under the Inflammatory Conditions Induced by TNF-\u03b1 in the C2C12 Cell Line","volume":"735","author":"Mohammadi","year":"2020","journal-title":"Gene"},{"key":"ref_45","doi-asserted-by":"crossref","unstructured":"Sarrami, Z., Sedghi, M., Mohammadi, I., Kim, W.K., and Mahdavi, A.H. (2022). Effects of Bacteriophage Supplement on the Growth Performance, Microbial Population, and PGC-1\u03b1 and TLR4 Gene Expressions of Broiler Chickens. Sci. Rep., 12.","DOI":"10.1038\/s41598-022-18663-1"},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1080\/1828051X.2021.2025161","article-title":"Effects of a Yeast Cell Wall Product on the Performance of Broiler Chickens and PGC-1\u03b1, TLR4, IL-10 and PPAR\u03b3 Genes Expression","volume":"21","author":"Sedghi","year":"2022","journal-title":"Ital. J. Anim. Sci."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2\u2212\u0394\u0394CT Method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.1093\/ps\/78.11.1561","article-title":"Evaluation of Dietary Supplements of Lipase, Detergent, and Crude Porcine Pancreas on Fat Utilization by Young Broiler Chicks","volume":"78","author":"Leeson","year":"1999","journal-title":"Poult. Sci."},{"key":"ref_49","unstructured":"Attia, Y.A., El-Hamid, A.E.A., Abdallah, A.A., Berikaa, M.A., El-Gandy, M.F., Sahin, K., Abou-Shehema, B.M., and von Einfluss, B. (2018). Vitamin C und Vitamin E Auf Die Eiqualit\u00e4t, Den Bruterfolg und Ausgew\u00e4hlte Indikatoren Der Lebe\u2014Und Nierenfunktion Bei Unter Hitzestress Gehaltenen Legehennen Des Zweinutzungstyps, Verlag Eugen Ulmer."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1017\/S000711451900182X","article-title":"Nutritional and Physiological Responses of Broiler Chickens to Dietary Supplementation with De-Oiled Soyabean Lecithin at Different Metabolisable Energy Levels and Various Fat Sources","volume":"122","author":"Majdolhosseini","year":"2019","journal-title":"Br. J. Nutr."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"593","DOI":"10.3382\/ps\/pew269","article-title":"Effects of Lysophospholipid Supplementation to Lower Nutrient Diets on Growth Performance, Intestinal Morphology, and Blood Metabolites in Broiler Chickens","volume":"96","author":"Boontiam","year":"2017","journal-title":"Poult. Sci."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1007\/s11250-008-9209-3","article-title":"Improving Productive and Reproductive Performance of Dual-Purpose Crossbred Hens in the Tropics by Lecithin Supplementation","volume":"41","author":"Attia","year":"2009","journal-title":"Trop. Anim. Health Prod."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"1564","DOI":"10.1111\/jpn.12966","article-title":"Effects of Lysolecithin and Xylanase Supplementation on the Growth Performance, Nutrient Digestibility and Lipogenic Gene Expression in Broilers Fed Low-Energy Wheat-Based Diets","volume":"102","author":"Hosseini","year":"2018","journal-title":"J. Anim. Physiol. Anim. Nutr."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"3473","DOI":"10.2527\/1992.70113473x","article-title":"Effects of Exogenous Emulsifiers and Fat Sources on Nutrient Digestibility, Serum Lipids, and Growth Performance in Weanling Pigs","volume":"70","author":"Jones","year":"1992","journal-title":"J. Anim. Sci."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1016\/0002-9610(80)90168-3","article-title":"Effects of Long-Term Ingestion of Soya Phospholipids on Serum Lipids in Humans","volume":"140","author":"Tompkins","year":"1980","journal-title":"Am. J. Surg."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"262604","DOI":"10.4061\/2010\/262604","article-title":"Effects of Supplemental Exogenous Emulsifier on Performance, Nutrient Metabolism, and Serum Lipid Profile in Broiler Chickens","volume":"2010","author":"Roy","year":"2010","journal-title":"Vet. Med. Int."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"711","DOI":"10.3748\/wjg.v21.i3.711","article-title":"Liver Enzymes, Metabolomics and Genome-Wide Association Studies: From Systems Biology to the Personalized Medicine","volume":"21","year":"2015","journal-title":"World J. Gastroenterol."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.aninu.2019.11.007","article-title":"Use of Nanoscale Metals in Poultry Diet as a Mineral Feed Additive","volume":"6","author":"Sizova","year":"2020","journal-title":"Anim. Nutr."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/0009-8981(90)90031-M","article-title":"The Human Alkaline Phosphatases: What We Know and What We Don\u2019t Know","volume":"186","author":"Harris","year":"1990","journal-title":"Clin. Chim. Acta"},{"key":"ref_60","first-page":"97","article-title":"Biochemical Markers of Bone Turnover: Part I: Biochemistry and Variability","volume":"26","author":"Seibel","year":"2005","journal-title":"Clin. Biochem. Rev."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"532","DOI":"10.3382\/japr\/pfy040","article-title":"Effect of High Dose of Bile Acids Supplementation in Broiler Feed on Growth Performance, Clinical Blood Metabolites, and Organ Development","volume":"27","author":"Lai","year":"2018","journal-title":"J. Appl. Poult. Res."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.foodchem.2014.01.090","article-title":"Effect of Antioxidant Potential of Tropical Fruit Juices on Antioxidant Enzyme Profiles and Lipid Peroxidation in Rats","volume":"157","author":"Pereira","year":"2014","journal-title":"Food Chem."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"R491","DOI":"10.1152\/ajpregu.00614.2005","article-title":"Free Radical Biology and Medicine: It\u2019s a Gas, Man!","volume":"291","author":"Pryor","year":"2006","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"2278","DOI":"10.1073\/pnas.051627098","article-title":"Increased Mitochondrial Oxidative Stress in the Sod2 (+\/-) Mouse Results in the Age-Related Decline of Mitochondrial Function Culminating in Increased Apoptosis","volume":"98","author":"Kokoszka","year":"2001","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"396","DOI":"10.3923\/ijp.2017.396.402","article-title":"Effect of Soy Lecithin on Growth Performance, Nutrient Digestibility and Hepatic Antioxidant Parameters of Broiler Chickens","volume":"13","author":"Siyal","year":"2017","journal-title":"Int. J. Pharmacol."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1017\/S0043933918000284","article-title":"Glutathione Peroxidases in Poultry Biology: Part 1. Classification and Mechanisms of Action","volume":"74","author":"Surai","year":"2018","journal-title":"Worlds. Poult. Sci. J."},{"key":"ref_67","doi-asserted-by":"crossref","unstructured":"El-katcha, M.I., Soltan, M.A., Shewita, R., Abdo, S.E., Sanad, A.S., Tufarelli, V., Alagawany, M., and El-naggar, K. (2021). Dietary Fiber and Lysolecithin Supplementation in Growing Ducks: Effect on Performance, Immune Response, Intestinal Morphology and Lipid Metabolism-regulating Genes. Animals, 11.","DOI":"10.3390\/ani11102873"},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1016\/S0021-9258(19)40252-4","article-title":"Protective Action of Phospholipid Hydroperoxide Glutathione Peroxidase against Membrane-Damaging Lipid Peroxidation. In Situ Reduction of Phospholipid and Cholesterol Hydroperoxides","volume":"265","author":"Thomas","year":"1990","journal-title":"J. Biol. Chem."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1111\/j.1439-0396.2006.00659.x","article-title":"Effect of Vitamin A and\/or e on Plasma Enzymatic Antioxidant Systems and Total Antioxidant Capacity of Broiler Chickens Challenged with Carbon Tetrachloride","volume":"91","author":"Mahmoud","year":"2007","journal-title":"J. Anim. Physiol. Anim. Nutr."},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1007\/s12192-018-0885-2","article-title":"Vitamin C and Sodium Bicarbonate Enhance the Antioxidant Ability of H9C2 Cells and Induce HSPs to Relieve Heat Stress","volume":"23","author":"Yin","year":"2018","journal-title":"Cell Stress Chaperones"},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/0309-1740(93)90046-K","article-title":"Methodology for Measuring Malonaldehyde as a Product of Lipid Peroxidation in Muscle Tissues: A Review","volume":"35","author":"Raharjo","year":"1993","journal-title":"Meat Sci."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1093\/ps\/85.3.476","article-title":"Effect of Antibiotic Growth Promoters on Broiler Performance, Intestinal Growth Parameters, and Quantitative Morphology","volume":"85","author":"Miles","year":"2006","journal-title":"Poult. Sci."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1111\/jpn.12747","article-title":"Effects of Milk Thistle Meal on Performance, Ileal Bacterial Enumeration, Jejunal Morphology and Blood Lipid Peroxidation in Laying Hens Fed Diets with Different Levels of Metabolizable Energy","volume":"102","author":"Mahdavi","year":"2018","journal-title":"J. Anim. Physiol. Anim. Nutr."},{"key":"ref_74","doi-asserted-by":"crossref","unstructured":"Wu, H., Wang, S., Tian, Y., Zhou, N., Wu, C., Li, R., Xu, W., Xu, T., Gu, L., and Ji, F. (2022). Effects of Hydroxylated Lecithin on Growth Performance, Serum Enzyme Activity, Hormone Levels Related to Lipid Metabolism and Meat Quality in Jiangnan White Goslings. Front. Vet. Sci., 9.","DOI":"10.3389\/fvets.2022.829338"},{"key":"ref_75","doi-asserted-by":"crossref","unstructured":"Chen, X., Wu, B., Shen, X.R., Wang, X., Ping, P., Miao, M., Liang, N., Yin, H., Shi, H., and Qian, J. (2023). Relevance of PUFA-Derived Metabolites in Seminal Plasma to Male Infertility. Front. Endocrinol., 14.","DOI":"10.3389\/fendo.2023.1138984"},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"1676","DOI":"10.1016\/j.bbapap.2009.11.023","article-title":"Nutrient-Dependent Regulation of PGC-1\u03b1\u2019s Acetylation State and Metabolic Function through the Enzymatic Activities of Sirt1\/GCN5","volume":"1804","author":"Dominy","year":"2010","journal-title":"Biochim. Biophys. Acta Proteins Proteom."},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1002\/hep.24066","article-title":"Hepatocyte Nuclear Factor-4 Alpha Regulates Liver Triglyceride Metabolism in Part through Secreted Phospholipase A2 GXIIB","volume":"53","author":"Guan","year":"2011","journal-title":"Hepatology"},{"key":"ref_78","unstructured":"Rhee, J. (2005). Partnership of HNF4\u03b1 with the Transcriptional Coactivator PGC-1\u03b1 in the Regulation of Hepatic Glucose and Lipid Homeostasis. [Ph.D. Thesis, Harvard University]."},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.1038\/nm.2439","article-title":"ATGL-Mediated Fat Catabolism Regulates Cardiac Mitochondrial Function via PPAR-\u00ce \u00b1 and PGC-1","volume":"17","author":"Haemmerle","year":"2011","journal-title":"Nat. Med."},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1007\/s00109-002-0384-9","article-title":"Lipoprotein Lipase: Structure, Function, Regulation, and Role in Disease","volume":"80","author":"Mead","year":"2002","journal-title":"J. Mol. Med."},{"key":"ref_81","unstructured":"Boonsinchai, N. (2015). Effect of Feeding Regimen and Age on Lipid Metabolism in Broiler Breeder Hens and Progeny. [Ph.D. Thesis, University of Arkansas]."},{"key":"ref_82","doi-asserted-by":"crossref","unstructured":"Shang, R., and Rodrigues, B. (2021). Lipoprotein Lipase and Its Delivery of Fatty Acids to the Heart. Biomolecules, 11.","DOI":"10.3390\/biom11071016"},{"key":"ref_83","doi-asserted-by":"crossref","unstructured":"Kumari, A., Kristensen, K.K., Ploug, M., and Lund Winther, A.M. (2021). The Importance of Lipoprotein Lipase Regulation in Atherosclerosis. Biomedicines, 9.","DOI":"10.3390\/biomedicines9070782"},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"1828","DOI":"10.1021\/bi00733a026","article-title":"Cofactor Activity of Protein Components of Human Very Low Density Lipoproteins in the Hydrolysis of Triglycerides by Lipoprotein Lipase from Different Sources","volume":"12","author":"Havel","year":"1973","journal-title":"Biochemistry"},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"2430","DOI":"10.7150\/jca.71619","article-title":"Research Progress in the Role and Mechanism of LPCAT3 in Metabolic Related Diseases and Cancer","volume":"19","author":"Shao","year":"2022","journal-title":"J. Cancer"},{"key":"ref_86","doi-asserted-by":"crossref","first-page":"1563","DOI":"10.1194\/jlr.M800398-JLR200","article-title":"Characterization of Human Lysophospholipid Acyltransferase 3","volume":"50","author":"Jian","year":"2009","journal-title":"J. Lipid Res."},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1111\/j.1365-2443.2008.01212.x","article-title":"Member of the Membrane-Bound O-Acyltransferase (MBOAT) Family Encodes a Lysophospholipid Acyltransferase with Broad Substrate Specificity","volume":"13","author":"Matsuda","year":"2008","journal-title":"Genes Cells"},{"key":"ref_88","doi-asserted-by":"crossref","first-page":"30235","DOI":"10.1074\/jbc.M806194200","article-title":"Lysophospholipid Acyltransferases and Arachidonate Recycling in Human Neutrophils","volume":"283","author":"Riekhof","year":"2008","journal-title":"J. Biol. Chem."},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"e06557","DOI":"10.7554\/eLife.06557","article-title":"Lpcat3-Dependent Production of Arachidonoyl Phospholipids Is a Key Determinant of Triglyceride Secretion","volume":"4","author":"Rong","year":"2015","journal-title":"eLife"},{"key":"ref_90","doi-asserted-by":"crossref","first-page":"20122","DOI":"10.1074\/jbc.M111.334664","article-title":"Lysophosphatidylcholine Acyltransferase 3 Knockdown-Mediated Liver Lysophosphatidylcholine Accumulation Promotes Very Low Density Lipoprotein Production by Enhancing Microsomal Triglyceride Transfer Protein Expression","volume":"287","author":"Li","year":"2012","journal-title":"J. Biol. Chem."},{"key":"ref_91","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1194\/jlr.M700184-JLR200","article-title":"Lysophosphatidylcholine as a Death Effector in the Lipoapoptosis of Hepatocytes","volume":"49","author":"Myoung","year":"2008","journal-title":"J. Lipid Res."},{"key":"ref_92","unstructured":"Feingold, K.R., Anawalt, B., Blackman, M.R., Boyce, A., Chrousos, G., Corpas, E., de Herder, W.W., Dhatariya, K., Dungan, K., and Hofland, J. (2000). Introduction to Lipids and Lipoproteins. Endotext, MDText.com, Inc."},{"key":"ref_93","unstructured":"Edwards, M., and Mohiuddin, S.S. (2022). Biochemistry, Lipolysis. StatPearls, StatPearls Publishing."},{"key":"ref_94","first-page":"791","article-title":"TGF-\u03b2 and Retinoic Acid: Regulators of Growth and Modifiers of Differentiation in Human Epidermal Cells","volume":"1","author":"Choi","year":"1990","journal-title":"Mol. Biol. Cell"},{"key":"ref_95","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.semnephrol.2012.04.008","article-title":"Retinoid and TGF-\u03b2 Families: Crosstalk in Development, Neoplasia, Immunity, and Tissue Repair","volume":"32","author":"Xu","year":"2012","journal-title":"Semin. Nephrol."},{"key":"ref_96","doi-asserted-by":"crossref","first-page":"bqz046","DOI":"10.1210\/endocr\/bqz046","article-title":"CPT1A-Mediated Fat Oxidation, Mechanisms, and Therapeutic Potential","volume":"161","author":"Schlaepfer","year":"2020","journal-title":"Endocrinol."},{"key":"ref_97","doi-asserted-by":"crossref","first-page":"2050","DOI":"10.1111\/cas.14011","article-title":"PGC1\u03b1\/CEBPB\/CPT1A Axis Promotes Radiation Resistance of Nasopharyngeal Carcinoma through Activating Fatty Acid Oxidation","volume":"110","author":"Du","year":"2019","journal-title":"Cancer Sci."},{"key":"ref_98","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.bbagrm.2018.12.009","article-title":"Epigenetic Regulation of Carnitine Palmitoyltransferase 1 (Cpt1a) by High Fat Diet","volume":"1862","author":"Moody","year":"2019","journal-title":"Biochim. Biophys. Acta Gene Regul. Mech."},{"key":"ref_99","first-page":"7","article-title":"A Novel Mutation in CPT1A Resulting in Hepatic CPT Deficiency","volume":"6","author":"Fontaine","year":"2012","journal-title":"JIMD Rep. Case Res. Rep."},{"key":"ref_100","doi-asserted-by":"crossref","first-page":"1324","DOI":"10.1194\/jlr.M048504","article-title":"Methylation at CPT1A Locus Is Associated with Lipoprotein Subfraction Profi Les","volume":"55","author":"Aslibekyan","year":"2014","journal-title":"J. Lipid Res."},{"key":"ref_101","doi-asserted-by":"crossref","unstructured":"Chen, Y., and Agellon, L.B. (2020). Distinct Alteration of Gene Expression Programs in the Small Intestine of Male and Female Mice in Response to Ablation of Intestinal Fabp Genes. Genes, 11.","DOI":"10.3390\/genes11080943"},{"key":"ref_102","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1146\/annurev.nutr.27.061406.093710","article-title":"The Emerging Functions and Mechanisms of Mammalian Fatty Acid-Binding Proteins","volume":"28","author":"Storch","year":"2008","journal-title":"Annu. Rev. Nutr."},{"key":"ref_103","first-page":"1587","article-title":"FABP1 Knockdown in Human Enterocytes Impairs Proliferation and Alters Lipid Metabolism","volume":"1862","author":"Scaglia","year":"2017","journal-title":"Biochim. Biophys. Acta Mol. Cell Biol. Lipids"},{"key":"ref_104","doi-asserted-by":"crossref","first-page":"17180","DOI":"10.1016\/S0021-9258(19)47356-0","article-title":"Selective Binding of Cholesterol by Recombinant Fatty Acid Binding Proteins","volume":"266","author":"Nemecz","year":"1991","journal-title":"J. Biol. Chem."},{"key":"ref_105","doi-asserted-by":"crossref","first-page":"9804","DOI":"10.1074\/jbc.RA120.013700","article-title":"Bilirubin Remodels Murine White Adipose Tissue by Reshaping Mitochondrial Activity and the Coregulator Profile of Peroxisome Proliferator-Activated Receptor A","volume":"295","author":"Gordon","year":"2020","journal-title":"J. Biol. Chem."},{"key":"ref_106","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1038\/nrd2589","article-title":"Fatty Acid-Binding Proteins: Role in Metabolic Diseases and Potential as Drug Targets","volume":"7","author":"Furuhashi","year":"2008","journal-title":"Nat. Rev. Drug Discov."},{"key":"ref_107","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.plefa.2014.10.001","article-title":"Enterocyte Fatty Acid-Binding Proteins (FABPs): Different Functions of Liver and Intestinal FABPs in the Intestine","volume":"93","author":"Gajda","year":"2015","journal-title":"Prostaglandins Leukot. Essent. Fat. Acids"},{"key":"ref_108","doi-asserted-by":"crossref","unstructured":"Patterson, E., Wall, R., Lisai, S., Ross, R.P., Dinan, T.G., Cryan, J.F., Fitzgerald, G.F., Banni, S., Quigley, E.M., and Shanahan, F. (2017). Bifidobacterium Breve with \u03b1-Linolenic Acid Alters the Composition, Distribution and Transcription Factor Activity Associated with Metabolism and Absorption of Fat. Sci. Rep., 7.","DOI":"10.1038\/srep43300"},{"key":"ref_109","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.freeradbiomed.2016.11.037","article-title":"Protective Effect of Quercetin on High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease in Mice Is Mediated by Modulating Intestinal Microbiota Imbalance and Related Gut-Liver Axis Activation","volume":"102","author":"Porras","year":"2017","journal-title":"Free Radic. Biol. Med."},{"key":"ref_110","doi-asserted-by":"crossref","first-page":"14890","DOI":"10.1074\/jbc.M010286200","article-title":"Palmitate-Induced Apoptosis Can Occur through a Ceramide-Independent Pathway","volume":"276","author":"Listenberger","year":"2001","journal-title":"J. Biol. Chem."},{"key":"ref_111","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1016\/j.jnutbio.2010.01.005","article-title":"Liver Fatty Acid-Binding Protein and Obesity","volume":"21","author":"Atshaves","year":"2010","journal-title":"J. Nutr. Biochem."},{"key":"ref_112","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1016\/j.bbalip.2011.09.010","article-title":"Fatty Acid Transport Proteins, Implications in Physiology and Disease","volume":"1821","author":"Kazantzis","year":"2012","journal-title":"Biochim. Biophys. Acta Mol. Cell Biol. Lipids"},{"key":"ref_113","doi-asserted-by":"crossref","unstructured":"Oeckinghaus, A., and Ghosh, S. (2009). The NF-KappaB Family of Transcription Factors and Its Regulation. Cold Spring Harb. Perspect. Biol., 1.","DOI":"10.1101\/cshperspect.a000034"},{"key":"ref_114","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1038\/cr.2010.175","article-title":"NF-\u039aB in the Regulation of Epithelial Homeostasis and Inflammation","volume":"21","author":"Wullaert","year":"2011","journal-title":"Cell Res."},{"key":"ref_115","doi-asserted-by":"crossref","unstructured":"Giuliani, C., Bucci, I., and Napolitano, G. (2018). The Role of the Transcription Factor Nuclear Factor-Kappa B in Thyroid Autoimmunity and Cancer. Front. Endocrinol., 9.","DOI":"10.3389\/fendo.2018.00471"},{"key":"ref_116","doi-asserted-by":"crossref","first-page":"FSO803","DOI":"10.2144\/fsoa-2022-0020","article-title":"The Role of Guggulsterone on the NF-\u039aB Pathway in Inflammatory Bowel Disease: Preclinical Evidence","volume":"8","author":"Priya","year":"2022","journal-title":"Futur. Sci. OA"},{"key":"ref_117","doi-asserted-by":"crossref","unstructured":"Yadav, H., and Rane, S.G. (2012). TGF-\u03b2\/Smad3 Signaling Regulates Brown Adipocyte Induction in White Adipose Tissue. Front. Endocrinol., 3.","DOI":"10.3389\/fendo.2012.00035"},{"key":"ref_118","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1093\/jb\/mvq052","article-title":"Autotaxin-An LPA Producing Enzyme with Diverse Functions","volume":"148","author":"Nakanaga","year":"2010","journal-title":"J. Biochem."},{"key":"ref_119","doi-asserted-by":"crossref","unstructured":"D\u2019Souza, K., Paramel, G.V., and Kienesberger, P.C. (2018). Lysophosphatidic Acid Signaling in Obesity and Insulin Resistance. Nutrients, 10.","DOI":"10.3390\/nu10040399"},{"key":"ref_120","doi-asserted-by":"crossref","first-page":"17023","DOI":"10.1038\/sigtrans.2017.23","article-title":"NF-\u039aB Signaling in Inflammation","volume":"2","author":"Liu","year":"2017","journal-title":"Signal Transduct. Target. Ther."},{"key":"ref_121","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1042\/bj3010801","article-title":"The Binding of Lysophospholipids to Rat Liver Fatty Acid-Binding Protein and Albumin","volume":"301","author":"Thumser","year":"1994","journal-title":"Biochem. J."},{"key":"ref_122","first-page":"1","article-title":"Triglyceride Metabolism in the Liver","volume":"8","author":"Cohen","year":"2018","journal-title":"Compr. Physiol."},{"key":"ref_123","doi-asserted-by":"crossref","unstructured":"Rodr\u00edguez-Calvo, R., Moreno-Vedia, J., Girona, J., Ibarretxe, D., Mart\u00ednez-Micaelo, N., Merino, J., Plana, N., and Masana, L. (2021). Relationship Between Fatty Acid Binding Protein 4 and Liver Fat in Individuals at Increased Cardiometabolic Risk. Front. Physiol., 12.","DOI":"10.3389\/fphys.2021.781789"},{"key":"ref_124","first-page":"23","article-title":"Fatty Acid-Binding Protein 4 (FABP4): Pathophysiological Insights and Potent Clinical Biomarker of Metabolic and Cardiovascular Diseases","volume":"8","author":"Furuhashi","year":"2014","journal-title":"Clin. Med. Insights Cardiol."},{"key":"ref_125","doi-asserted-by":"crossref","unstructured":"Lamas Bervejillo, M., Bonanata, J., Franchini, G.R., Richeri, A., Marqu\u00e9s, J.M., Freeman, B.A., Schopfer, F.J., Coiti\u00f1o, E.L., C\u00f3rsico, B., and Rubbo, H. (2020). A FABP4-PPAR\u03b3 Signaling Axis Regulates Human Monocyte Responses to Electrophilic Fatty Acid Nitroalkenes. Redox Biol., 29.","DOI":"10.1016\/j.redox.2019.101376"},{"key":"ref_126","doi-asserted-by":"crossref","unstructured":"Ahmad, F., Chung, Y.W., Tang, Y., Hockman, S.C., Liu, S., Khan, Y., Huo, K., Billings, E., Amar, M.J., and Remaley, A.T. (2016). Phosphodiesterase 3B (PDE3B) Regulates NLRP3 Inflammasome in Adipose Tissue. Sci. Rep., 6.","DOI":"10.1038\/srep28056"},{"key":"ref_127","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1007\/s00011-019-01273-5","article-title":"The Effect of Palmitic Acid on Inflammatory Response in Macrophages: An Overview of Molecular Mechanisms","volume":"68","author":"Korbecki","year":"2019","journal-title":"Inflamm. Res."}],"container-title":["Animals"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2076-2615\/14\/21\/3066\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T16:19:44Z","timestamp":1760113184000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2076-2615\/14\/21\/3066"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,24]]},"references-count":127,"journal-issue":{"issue":"21","published-online":{"date-parts":[[2024,11]]}},"alternative-id":["ani14213066"],"URL":"https:\/\/doi.org\/10.3390\/ani14213066","relation":{},"ISSN":["2076-2615"],"issn-type":[{"value":"2076-2615","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10,24]]}}}