{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:37:47Z","timestamp":1760146667741,"version":"build-2065373602"},"reference-count":53,"publisher":"MDPI AG","issue":"23","license":[{"start":{"date-parts":[[2024,11,25]],"date-time":"2024-11-25T00:00:00Z","timestamp":1732492800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Science and Technology Program of Shijiazhuang City","award":["236490539A","CAAS-IFR-ZDRW202302","1610382024005"],"award-info":[{"award-number":["236490539A","CAAS-IFR-ZDRW202302","1610382024005"]}]},{"name":"Agricultural Science and Technology Innovation Program of the Institute of Feed Research of the Chinese Academy of Agricultural Sciences","award":["236490539A","CAAS-IFR-ZDRW202302","1610382024005"],"award-info":[{"award-number":["236490539A","CAAS-IFR-ZDRW202302","1610382024005"]}]},{"name":"Central Public-interest Scientific Institution Basal Research Fund","award":["236490539A","CAAS-IFR-ZDRW202302","1610382024005"],"award-info":[{"award-number":["236490539A","CAAS-IFR-ZDRW202302","1610382024005"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animals"],"abstract":"<jats:p>To evaluate the phytobiotic effect of Anacardium occidentale leaf powder (AOLP) on growth performance, diarrhea incidence, blood biochemistry, and intestinal traits, seventy-two weaned piglets were randomly distributed into four groups (six replicates\/group and three pigs\/replicate) for 28 days, receiving a control diet (T0) or being supplemented with 5 (T1), 10 (T2), or 15 (T3) g\/kg of AOLP. The diets did not affect the growth performance (p &gt; 0.05); however, the AOLP groups had a decreased diarrhea incidence and malondialdehyde concentration (p &lt; 0.05; 28 days). However, the AOLP groups had increased immunoglobulins (G and M) and villus heights (p &lt; 0.05) in the duodenum. Likewise, T3 improved the number of goblet cells in the villi and the whole intestine (p &lt; 0.01), the Mucin2 area in the jejunum and ileum (p &lt; 0.05), occludin gene expression in the jejunum (p &lt; 0.01), and acetic and valeric acid production (p &lt; 0.05). Microbial diversity at the genus level was not different (p &gt; 0.05); however, T3 increased the abundance of the Lactobacillus genus. These findings suggest that dietary supplementation with AOLP improved intestinal health by increasing antioxidant, immune, anti-inflammatory, and antidiarrheal activity in the weaned piglets.<\/jats:p>","DOI":"10.3390\/ani14233382","type":"journal-article","created":{"date-parts":[[2024,11,25]],"date-time":"2024-11-25T06:25:19Z","timestamp":1732515919000},"page":"3382","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Effect of Anacardium occidentale Leaf Powder on Growth Performance, Diarrhea Incidence, Blood Biochemistry, and Intestinal Traits in Weaned Piglets"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3940-1026","authenticated-orcid":false,"given":"Roisbel","family":"Aroche","sequence":"first","affiliation":[{"name":"Key Laboratory of Feed Biotechnology of the Ministry of Agriculture and Rural Affairs, Institute of Feed Research, Chinese Academy of Agricultural Sciences, Beijing 100081, China"},{"name":"Department of Animal Husbandry, Faculty of Agricultural Sciences, University of Granma, Bayamo 85100, Cuba"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-6166-5633","authenticated-orcid":false,"given":"Ge","family":"Gao","sequence":"additional","affiliation":[{"name":"Key Laboratory of Feed Biotechnology of the Ministry of Agriculture and Rural Affairs, Institute of Feed Research, Chinese Academy of Agricultural Sciences, Beijing 100081, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanpin","family":"Li","sequence":"additional","affiliation":[{"name":"Key Laboratory of Feed Biotechnology of the Ministry of Agriculture and Rural Affairs, Institute of Feed Research, Chinese Academy of Agricultural Sciences, Beijing 100081, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yonggang","family":"Zhang","sequence":"additional","affiliation":[{"name":"Huanshan Group Co., Ltd., Qingdao 266000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rom\u00e1n","family":"Rodr\u00edguez","sequence":"additional","affiliation":[{"name":"Animal Production Study Center, Faculty of Agricultural Sciences, University of Granma, Bayamo 85100, Cuba"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2167-4904","authenticated-orcid":false,"given":"Yordan","family":"Mart\u00ednez","sequence":"additional","affiliation":[{"name":"Faculty of Veterinary Medicine, University of Fondwa, L\u00e9og\u00e2ne 6210, Haiti"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xilong","family":"Li","sequence":"additional","affiliation":[{"name":"Key Laboratory of Feed Biotechnology of the Ministry of Agriculture and Rural Affairs, Institute of Feed Research, Chinese Academy of Agricultural Sciences, Beijing 100081, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,11,25]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Xu, Q., Jian, H., Zhao, W., Li, J., Zou, X., and Dong, X. 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