{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:41:54Z","timestamp":1760146914977,"version":"build-2065373602"},"reference-count":92,"publisher":"MDPI AG","issue":"24","license":[{"start":{"date-parts":[[2024,12,20]],"date-time":"2024-12-20T00:00:00Z","timestamp":1734652800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animals"],"abstract":"<jats:p>Nasal carcinomas in dogs are locally invasive neoplasms with a low metastatic rate that pose significant treatment challenges due to their location and aggressiveness. This study evaluates the safety, feasibility, and therapeutic outcomes of computed tomography-guided radiofrequency ablation (CT-guided RFA) in 15 dogs diagnosed with nasal adenocarcinoma. All patients underwent staging and histopathological diagnosis before treatment. CT-guided RFA achieved a significant tumor volume reduction (82.8%) and improvement in clinical signs such as nasal discharge, epistaxis, and respiratory distress, without complications. Post-RFA CT examinations demonstrated a significant decrease in Hounsfield units and tumor volume. This study has shown that CT-guided RFA is an effective cytoreductive option for minimally invasive management of nasal adenocarcinomas in dogs, particularly when traditional therapies like radiation therapy or surgery are not feasible.<\/jats:p>","DOI":"10.3390\/ani14243682","type":"journal-article","created":{"date-parts":[[2024,12,20]],"date-time":"2024-12-20T06:44:33Z","timestamp":1734677073000},"page":"3682","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Computed Tomography-Guided Radiofrequency Ablation of Nasal Carcinomas in Dogs"],"prefix":"10.3390","volume":"14","author":[{"given":"Mar\u00eda Dolores","family":"Alf\u00e9rez","sequence":"first","affiliation":[{"name":"VetCorner Unavets, 50012 Zaragoza, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9771-4143","authenticated-orcid":false,"given":"Andrea","family":"Corda","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine, University of Sassari, 07100 Sassari, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1204-4356","authenticated-orcid":false,"given":"Ignacio","family":"de Blas","sequence":"additional","affiliation":[{"name":"Department of Animal Pathology, University of Zaragoza, 50013 Zaragoza, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4694-6120","authenticated-orcid":false,"given":"Lucas","family":"Gago","sequence":"additional","affiliation":[{"name":"Department of Mathematics and Computer Science, University of Barcelona, 08007 Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Telmo","family":"Fernandes","sequence":"additional","affiliation":[{"name":"Imaginologia Veterinaria do Porto, 4490-479 Porto, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ignacio","family":"Rodr\u00edguez-Piza","sequence":"additional","affiliation":[{"name":"Anicura Gl\u00f2ries Hospital Veterinari, 08010 Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beatriz","family":"Bala\u00f1\u00e1","sequence":"additional","affiliation":[{"name":"Hospital Anicura Aralar Veterinarios, 50410 Zaragoza, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3464-2231","authenticated-orcid":false,"given":"Plamena","family":"Pentcheva","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine, University of Sassari, 07100 Sassari, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Javier","family":"Caruncho","sequence":"additional","affiliation":[{"name":"Arealonga Veterinary Clinic, 15190 A Coru\u00f1a, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alicia","family":"Barbero-Fern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Imaging, European University, 28670 Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jorge","family":"Llin\u00e1s","sequence":"additional","affiliation":[{"name":"Hospital Anicura Valencia Sur, 46460 Valencia, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Rivas","sequence":"additional","affiliation":[{"name":"Hospital Anicura Aralar Veterinarios, 50410 Zaragoza, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amaia","family":"Escudero","sequence":"additional","affiliation":[{"name":"Hospital Anicura Aralar Veterinarios, 50410 Zaragoza, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9193-7661","authenticated-orcid":false,"given":"Pablo","family":"G\u00f3mez-Ochoa","sequence":"additional","affiliation":[{"name":"VetCorner Unavets, 50012 Zaragoza, Spain"},{"name":"Department of Animal Pathology, University of Zaragoza, 50013 Zaragoza, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,12,20]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"e55501","DOI":"10.5326\/JAAHA-MS-6901","article-title":"Hydropulsion as Palliative, Long-Term, Last-Resort Treatment of Nasal Carcinoma in a Dog and a Cat","volume":"55","author":"Bienes","year":"2019","journal-title":"J. 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