{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T00:34:48Z","timestamp":1759970088320,"version":"build-2065373602"},"reference-count":45,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2025,1,10]],"date-time":"2025-01-10T00:00:00Z","timestamp":1736467200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior (CAPES)","award":["88887.673547\/2022-00"],"award-info":[{"award-number":["88887.673547\/2022-00"]}]},{"name":"PROPESP\/UFPA","award":["88887.673547\/2022-00"],"award-info":[{"award-number":["88887.673547\/2022-00"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animals"],"abstract":"<jats:p>Manatees are semi-social animals, with the mother\u2013calf relationship being considered long-lasting for the species. However, some events lead to the separation of this pair. Orphaned manatee calves can be adopted by other females of the same species. However, if this does not happen and a healthy calf strand is rescued, immediate release represents the best option for the individual. But when immediate release becomes unviable, the animals are taken to rehabilitation centers and can die from various causes. A newborn Antillean manatee was rescued in the north of Brazil, and the attempt at immediate release was unsuccessful; three months later, the animal died. At necropsy, it was observed that the brain was soft and friable, collapsing when placed on a surface, with the corpus callosum region able to be ruptured easily and the cerebral hemispheres lying flaccid. The analysis of serial sections of the brain showed dilated lateral ventricles and a reduction in white matter, making it possible to affirm the presence of congenital hydrocephalus, the main factor that may have led to the abandonment of the offspring.<\/jats:p>","DOI":"10.3390\/ani15020161","type":"journal-article","created":{"date-parts":[[2025,1,10]],"date-time":"2025-01-10T03:48:11Z","timestamp":1736480891000},"page":"161","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Neonatal Abandonment and Hydrocephalus in Antillean Manatees (Trichechus manatus manatus): Is There a Causal Relationship?"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9238-3875","authenticated-orcid":false,"given":"Tiago F. S.","family":"Santos","sequence":"first","affiliation":[{"name":"Animal Pathology Laboratory (LAPATO), Institute of Veterinary Medicine (IMV), Federal University of Par\u00e1 (UFPA), Castanhal 68745-000, PA, Brazil"},{"name":"Bicho D\u2019\u00e1gua Institute: Socio-Environmental Conservation (IBD), Soure 68870-000, PA, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5852-5609","authenticated-orcid":false,"given":"M\u00e1rcio A. O.","family":"Moura","sequence":"additional","affiliation":[{"name":"Animal Pathology Laboratory (LAPATO), Institute of Veterinary Medicine (IMV), Federal University of Par\u00e1 (UFPA), Castanhal 68745-000, PA, Brazil"},{"name":"Bicho D\u2019\u00e1gua Institute: Socio-Environmental Conservation (IBD), Soure 68870-000, PA, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriel S. F.","family":"Tavares","sequence":"additional","affiliation":[{"name":"Animal Pathology Laboratory (LAPATO), Institute of Veterinary Medicine (IMV), Federal University of Par\u00e1 (UFPA), Castanhal 68745-000, PA, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julyanne S.","family":"Siqueira","sequence":"additional","affiliation":[{"name":"Animal Pathology Laboratory (LAPATO), Institute of Veterinary Medicine (IMV), Federal University of Par\u00e1 (UFPA), Castanhal 68745-000, PA, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nat\u00e1lia M. F. P.","family":"Sarmento","sequence":"additional","affiliation":[{"name":"Animal Pathology Laboratory (LAPATO), Institute of Veterinary Medicine (IMV), Federal University of Par\u00e1 (UFPA), Castanhal 68745-000, PA, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert G. S.","family":"Prado","sequence":"additional","affiliation":[{"name":"Animal Pathology Laboratory (LAPATO), Institute of Veterinary Medicine (IMV), Federal University of Par\u00e1 (UFPA), Castanhal 68745-000, PA, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7560-0113","authenticated-orcid":false,"given":"Alexandra F.","family":"Costa","sequence":"additional","affiliation":[{"name":"Bicho D\u2019\u00e1gua Institute: Socio-Environmental Conservation (IBD), Soure 68870-000, PA, Brazil"},{"name":"Chico Mendes Institute for Biodiversity Conservation (ICMBio), Coral Coast Environmental Protection Area (APACC), Tamandar\u00e9 55578-000, PE, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tayanna M. M. M.","family":"Amaral","sequence":"additional","affiliation":[{"name":"Bicho D\u2019\u00e1gua Institute: Socio-Environmental Conservation (IBD), Soure 68870-000, PA, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5593-1449","authenticated-orcid":false,"given":"Renata","family":"Emin-Lima","sequence":"additional","affiliation":[{"name":"Bicho D\u2019\u00e1gua Institute: Socio-Environmental Conservation (IBD), Soure 68870-000, PA, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maura E. M.","family":"Sousa","sequence":"additional","affiliation":[{"name":"Bicho D\u2019\u00e1gua Institute: Socio-Environmental Conservation (IBD), Soure 68870-000, PA, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8861-6234","authenticated-orcid":false,"given":"Reginaldo H. M.","family":"Moreira J\u00fanior","sequence":"additional","affiliation":[{"name":"Bicho D\u2019\u00e1gua Institute: Socio-Environmental Conservation (IBD), Soure 68870-000, PA, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1014-2999","authenticated-orcid":false,"given":"Pedro S.","family":"Bezerra J\u00fanior","sequence":"additional","affiliation":[{"name":"Animal Pathology Laboratory (LAPATO), Institute of Veterinary Medicine (IMV), Federal University of Par\u00e1 (UFPA), Castanhal 68745-000, PA, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriela","family":"Riet-Correa","sequence":"additional","affiliation":[{"name":"Animal Pathology Laboratory (LAPATO), Institute of Veterinary Medicine (IMV), Federal University of Par\u00e1 (UFPA), Castanhal 68745-000, PA, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1622-9849","authenticated-orcid":false,"given":"Val\u00edria D.","family":"Cerqueira","sequence":"additional","affiliation":[{"name":"Animal Pathology Laboratory (LAPATO), Institute of Veterinary Medicine (IMV), Federal University of Par\u00e1 (UFPA), Castanhal 68745-000, PA, Brazil"},{"name":"Bicho D\u2019\u00e1gua Institute: Socio-Environmental Conservation (IBD), Soure 68870-000, PA, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,1,10]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Hartman, D. (1979). Ecology and Behavior of the Manatee (Trichechus manatus) in Florida, American Society of Mammalogists.","DOI":"10.5962\/bhl.title.39474"},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Marsh, H., O\u2019shea, T.J., and Reynolds, J.E. (2011). Behavior and Habitat use. Ecology and Conservation of the Sirenia: Dugongs and Manatees, Cambridge University Press.","DOI":"10.1017\/CBO9781139013277"},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"Hamlett, W.C. (1992). Reproductive Biology of South American Manatees. Reproductive Biology of South American Vertebrates, Springer.","DOI":"10.1007\/978-1-4612-2866-0"},{"key":"ref_4","unstructured":"W\u00fcrsig, B., Thewissen, J.G.M., and Kovacs, K.M. (2018). Sirenian life history. Encyclopedia of Marine Mammals, Academic Press."},{"key":"ref_5","unstructured":"Reep, R.L., and Bonde, R.K. (2021). The Florida Manatee Biology and Conservation, University Press of Florida."},{"key":"ref_6","first-page":"26","article-title":"Epimeletic behavior in a Florida Manatee","volume":"70","author":"Tennant","year":"2019","journal-title":"Sirenews"},{"key":"ref_7","doi-asserted-by":"crossref","unstructured":"Marsh, H. (2022). Chapter 4\u2013Social and Reproductive Behaviors in Ethology and Behavioral Ecology of Sirenia, Springer Nature Switzerland AG.","DOI":"10.1007\/978-3-030-90742-6"},{"key":"ref_8","unstructured":"Lima, R.P. (1997). Peixe-boi marinho (Trichechus manatus): Distribui\u00e7\u00e3o, Status de Conserva\u00e7\u00e3o e Aspectos Tradicionais ao longo do litoral nordeste do Brasil. [Mestrado Disserta\u00e7\u00e3o, Oceanografia Biol\u00f3gica, Universidade Federal de Pernambuco]. 87f."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"69","DOI":"10.5597\/lajam00050","article-title":"Strandings of Antillean manatees (Trichechus manatus) in northeastern Brazil","volume":"3","author":"Parente","year":"2004","journal-title":"Lat. Am. J. Aquat. Mamm."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1111\/j.1469-7998.2009.00655.x","article-title":"The lesser of two evils: Seasonal migrations of Amazonian manatees in the Western Amazon","volume":"280","author":"Arraut","year":"2010","journal-title":"J. Zool."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"113","DOI":"10.5597\/lajam00291","article-title":"Hunting and hunters of the Amazonian manatee in a Brazilian protected area","volume":"17","author":"Calvimontes","year":"2022","journal-title":"Lat. Am. J. Aquat. Mamm."},{"key":"ref_12","unstructured":"Bonde, R.K. (2009). Population Genetics and Conservation of the Florida Manatee: Past, Present and Future. [Ph.D. Dissertation, University of Florida]."},{"key":"ref_13","first-page":"30","article-title":"Biological versus foster Antillean manatee calf: Who receives more social interaction from mother?","volume":"11","author":"Liu","year":"2017","journal-title":"Univ. Toronto J. Undergrad. Life Sci."},{"key":"ref_14","unstructured":"Deutsch, C.J., Self-Sullivan, C., and Mignucci-Giannoni, A. (2024, April 25). Trichechus manatus. The IUCN Red List of Threatened Species 2008: (e.T22103A9356917). Available online: https:\/\/www.iucnredlist.org\/species\/22103\/9356917."},{"key":"ref_15","unstructured":"Luna, F.O., Balensiefer, D.C., Fragoso, A.B., Stephano, A., and Attademo, F.L.N. (2018). Trichechus manatus Linnaeus, 1758, p. 103\u2013109. Instituto Chico Mendes de Conserva\u00e7\u00e3o da Biodiversidade (orgs). Livro Vermelho da Fauna Brasileira Amea\u00e7ada de Extin\u00e7\u00e3o: Volume II\u2013Mam\u00edferos, ICMBio\/MMA."},{"key":"ref_16","unstructured":"Attademo, F.L.N., Miranda, A.V., Torres-Florez, J.P., Sousa, G.P., Fruet, P.F., and Luna, F.O. (2022). (Orgs). Atendimento a Peixes-Bois Encalhados e Transporte de Filhotes, ICMBio."},{"key":"ref_17","unstructured":"Normande, I.C., Attademo, F.L.N., Luna, F.O., and Soorae, P.S. (2016). Antillean manatee release program in Brazil. Global Re-Introduction Perspectives, IUCN."},{"key":"ref_18","first-page":"1768","article-title":"Doen\u00e7as infecciosas e n\u00e3o infecciosas nos peixes-boi do Brasil","volume":"48","author":"Attademo","year":"2020","journal-title":"Acta Sci. Vet."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.jcpa.2018.10.173","article-title":"Cerebral and cardiac congenital malformations in neonatal West Indian manatees (Trichechus manatus)","volume":"166","author":"Carvalho","year":"2019","journal-title":"J. Comp. Pathol."},{"key":"ref_20","unstructured":"Maxie, M.M. (2016). Nervous System in Jubb, Kennedy, and Palmer\u2019s Pathology of Domestic Animals, Elsevier."},{"key":"ref_21","unstructured":"Bonde, R.K., Beck, C.A., and O'shea, T.J. (1983). Manual of Procedures for the Salvage and Necropsy of Carcasses of the West Indian Manatee (Trichechus manatus), Denver Wildlife Research Center."},{"key":"ref_22","unstructured":"Behmer, O.A., Tolosa, E.M.C., Neto, A.G.F., and Rodrigues, J. (2013). Manual de T\u00e9cnicas para Histologia Normal e Patol\u00f3gica, Editora Manole."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"1940082917728375","DOI":"10.1177\/1940082917728375","article-title":"Three decades of Antillean manatee (Trichechus manatus manatus) stranding along the Brazilian coast","volume":"10","author":"Balensiefer","year":"2017","journal-title":"Trop. Conserv. Sci."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1177\/0300985810388525","article-title":"Marine mammals as sentinel species for oceans and human health","volume":"48","author":"Bossart","year":"2011","journal-title":"Vet. Pathol."},{"key":"ref_25","unstructured":"W\u00fcrsig, B., Thewissen, J.G.M., and Kovacs, K.M. (2018). Manatees: Trichechus manatus, T. senegalensis, and T. inunguis. Encyclopedia of Marine Mammals, Academic Press."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"168","DOI":"10.22456\/1807-9806.26382","article-title":"Caracteriza\u00e7\u00e3o de dep\u00f3sitos sedimentares recentes da por\u00e7\u00e3o superior da Ba\u00eda de Maraj\u00f3 (margem leste do estu\u00e1rio do Rio Par\u00e1, Amaz\u00f4nia)","volume":"38","author":"Martins","year":"2011","journal-title":"Pesqui. Geoci\u00eancias"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"573","DOI":"10.46357\/bcnaturais.v15i3.246","article-title":"Distribution of South American manatees, Trichechus manatus Linnaeus, 1758 and T. inunguis (Natterer, 1883) (Sirenia: Trichechidae)","volume":"15","author":"Bonvicino","year":"2020","journal-title":"Bol. Mus. Para. Em\u00edlio Goeldi-Ci\u00eancias Nat."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/0006-3207(81)90044-6","article-title":"Distribution and status of manatees Trichechus spp. near the mouth of the Amazon River, Brazil","volume":"19","author":"Domning","year":"1981","journal-title":"Biol. Conserv."},{"key":"ref_29","first-page":"34","article-title":"Going back to my roots: Confirmed sightings of the Antillean manatee (Trichechus manatus) on the coast of Ilha de Maraj\u00f3, northern Brazilian coast","volume":"6","author":"Siciliano","year":"2007","journal-title":"J. Mar. Biol. Assoc. UK"},{"key":"ref_30","first-page":"e27787v1","article-title":"Polymorphisms and distribution of South American manatees (Trichechus spp.)","volume":"7","author":"Bonvicino","year":"2019","journal-title":"PeerJ Prepr."},{"key":"ref_31","unstructured":"Attademo, F.L.N., Gomes, G.L., Silva, F.J.L., Moreira, A.B., Freire, A.C.B., S\u00e1-Leit\u00e3o, H.C.M., and Luna, F.O. (2020). Comportamento de Peixes-Bois\u2013Guia Ilustrado, ICMBio."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1097\/00003086-198601000-00042","article-title":"Congenital malformations of the flipper in three West Indian manatees, Trichechus manatus, and a proposed mechanism for development of ectrodactyly and cleft hand in mammals","volume":"202","author":"Watson","year":"1986","journal-title":"Clin. Orthop. Relat. Res."},{"key":"ref_33","first-page":"507","article-title":"Manatee medicine. Zoo & Wild Animal Medicine","volume":"4","author":"Walsh","year":"1999","journal-title":"Curr. Ther."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1007\/s002679910015","article-title":"Manatee mortality in Puerto Rico","volume":"25","author":"Williams","year":"2000","journal-title":"Environ. Manag."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"111","DOI":"10.3354\/dao03639","article-title":"Manatee Trichechus manatus latirostris calf mortality in Florida: A retrospective review of pathology data from 2009\u20132017","volume":"147","author":"Weisbrod","year":"2021","journal-title":"Dis. Aquat. Org."},{"key":"ref_36","first-page":"120","article-title":"Oral cleft in an Amazonian manatee (Trichechus inunguis) (Mammalia, Sirenia)","volume":"19","author":"Rosas","year":"2024","journal-title":"Lat. Am. J. Aquat. Mamm."},{"key":"ref_37","unstructured":"Meirelles, A.C.O., and Carvalho, V.L. (2016). Gen\u00e9tica in Peixe-Boi Marinho: Biologia e Conserva\u00e7\u00e3o no Brasil, Aquasis, Bambu Editora e Artes Gr\u00e1ficas."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1053\/jcpa.2000.0428","article-title":"Histological observations on the brains of symptomless 7-year-old cattle","volume":"124","author":"Wells","year":"2001","journal-title":"J. Comp. Pathol."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1159\/000113381","article-title":"Manatee cerebral cortex: Cytoarchitecture of the caudal region in Trichechus manatus latirostris","volume":"45","author":"Marshall","year":"1995","journal-title":"Brain Behav. Evol."},{"key":"ref_40","doi-asserted-by":"crossref","unstructured":"Vonk, J., and Shackelford, T.K. (2022). Sirenia Sensory Systems in Encyclopedia of Animal Cognition and Behavior, Springer Nature Switzerland AG.","DOI":"10.1007\/978-3-319-55065-7"},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1038\/eye.1996.64","article-title":"Cortical visual dysfunction in children: A clinical study","volume":"10","author":"Dutton","year":"1996","journal-title":"Eye"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1354\/vp.44-5-713","article-title":"Internal hydrocephalus and associated periventricular encephalitis in a young fox","volume":"44","author":"Mandara","year":"2007","journal-title":"Vet. Pathol."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"1741","DOI":"10.1292\/jvms.17-0075","article-title":"Acute blindness in a dog with Acinetobacter-associated postencephalitic hydrocephalus","volume":"79","author":"Kim","year":"2017","journal-title":"J. Vet. Med. Sci."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1111\/j.1469-7998.1872.tb08571.x","article-title":"On the Form and Structure of the Manatee (Manatus americanus)","volume":"8","author":"Murie","year":"1870","journal-title":"Trans. Zool. Soc. Lond."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1159\/000115866","article-title":"Regional brain morphometry and lissencephaly in the Sirenia","volume":"35","author":"Reep","year":"1990","journal-title":"Brain Behav. Evol."}],"container-title":["Animals"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2076-2615\/15\/2\/161\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T10:26:06Z","timestamp":1759919166000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2076-2615\/15\/2\/161"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,10]]},"references-count":45,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2025,1]]}},"alternative-id":["ani15020161"],"URL":"https:\/\/doi.org\/10.3390\/ani15020161","relation":{},"ISSN":["2076-2615"],"issn-type":[{"type":"electronic","value":"2076-2615"}],"subject":[],"published":{"date-parts":[[2025,1,10]]}}}