{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T15:47:45Z","timestamp":1783612065747,"version":"3.55.0"},"reference-count":40,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2025,1,12]],"date-time":"2025-01-12T00:00:00Z","timestamp":1736640000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animals"],"abstract":"<jats:p>The clinical outcomes of laparoscopic-assisted ovariohysterectomy for the treatment of hydrometra or pyometra in small-sized dogs have not been reported. This study aimed to retrospectively investigate the clinical outcomes of two-port laparoscopic-assisted ovariohysterectomy in small-sized dogs weighing &lt; 6 kg with mild to moderate hydrometra or pyometra. Laparoscopic ports were placed at the umbilicus on the midline, as well as at the midpoint between the umbilicus and pelvic brim. While the uterine horn was externally retracted, the cervical region was ligated and transected. A total of 77 dogs were included, with a median age of 8.8 years (range: 10 months to 16.1 years) and a median weight of 3 (range: 1.26\u20136.0) kg. Clinical signs included lethargy, anorexia, polydipsia, and polyuria; 51 dogs (66%) were asymptomatic, with an enlarged uterus incidentally detected during health checkups. Histopathological analysis revealed hydrometra and pyometra in 51 and 26 dogs, respectively. The median operative time was 32 (range: 15\u201383) minutes, and the median hospital stay was 0 (range: 0\u20133) days. No intraoperative complications occurred, although 18 dogs experienced anorexia postoperatively, and 3 showed signs of incision site infection. All sutures were removed 7\u201310 days postoperatively, and all dogs were clinically healthy at the two-week follow-up. The findings indicate that two-port laparoscopic-assisted ovariohysterectomy is a safe and effective treatment option for managing mild to moderate hydrometra and pyometra in small-sized dogs.<\/jats:p>","DOI":"10.3390\/ani15020187","type":"journal-article","created":{"date-parts":[[2025,1,13]],"date-time":"2025-01-13T04:01:52Z","timestamp":1736740912000},"page":"187","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Optimized Two-Port Laparoscopic-Assisted Ovariohysterectomy for Hydrometra and Pyometra in Small-Sized Dogs"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4191-287X","authenticated-orcid":false,"given":"Young-Tae","family":"Park","sequence":"first","affiliation":[{"name":"Ve. C. Jiyugaoka Animal Medical Center, Meguroku 152-0023, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6245-2382","authenticated-orcid":false,"given":"Tomomi","family":"Minamoto","sequence":"additional","affiliation":[{"name":"Evergreen Vet Research & Publication, Ichinomiya 491-0914, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,1,12]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1111\/rda.12331","article-title":"Diagnostic and Prognostic Markers for Uterine Diseases in Dogs","volume":"49","author":"Hagman","year":"2014","journal-title":"Reprod. Domest. 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