{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:04:54Z","timestamp":1760058294197,"version":"build-2065373602"},"reference-count":46,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2025,3,30]],"date-time":"2025-03-30T00:00:00Z","timestamp":1743292800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Dr. E. Graeub AG, Rehhagstrasse 83, CH-3018 Bern, Switzerland, and the Specialization Committee (SpezKo) of the Vetsuisse Faculty, University of Bern, CH-3012 Bern, Switzerland"},{"name":"laboRvet, Wiggermatte 16, CH-6260 Reiden, Switzerland"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animals"],"abstract":"<jats:p>In dairy cattle, ovarian cysts (COFs) represent a major cause of infertility. They can be divided morphologically into follicular and luteal cysts based on their wall thickness, which can be examined by ultrasound, and progesterone secretion, which can be analyzed in serum or milk. The aim of our study was to evaluate cyst recovery using a modified ovsynch protocol with no need to differentiate COFs. Additionally, the beta-hydroxybutyric acid level (BHB), progesterone values, and trace elements in the serum were measured when therapy started. Fourteen days after treatment, COF recovery was confirmed in 88% of the cases. The median calving-to-conception interval, number of artificial inseminations until pregnancy, and median number of days from treatment to pregnancy were not different between the modified ovsynch protocol group and all other COF treatments. The logistic regression for COF included the parameters group, the cyst type, breed, the number of artificial inseminations (AIs), calving to conception cut at 200 d p.p., the cyst size, and therapy. The backward (and also forward) variable selection of the logistic regression yielded only the cyst size as a significant negative impact factor for recovery. In conclusion, the modified ovsynch protocol is a useful, practical option for COF treatment with the advantage of not needing to differentiate between the two cyst types.<\/jats:p>","DOI":"10.3390\/ani15070995","type":"journal-article","created":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T04:21:01Z","timestamp":1743481261000},"page":"995","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Efficiency of a Modified Ovulation Synchronization Program in the Treatment of Ovarian Cysts in Dairy Cattle"],"prefix":"10.3390","volume":"15","author":[{"given":"Daniela","family":"Haldi","sequence":"first","affiliation":[{"name":"Clinic for Ruminants, Vetsuisse Faculty, University of Bern, Bremgartenstrasse 109a, CH-3012 Bern, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eveline","family":"Studer","sequence":"additional","affiliation":[{"name":"Clinic for Ruminants, Vetsuisse Faculty, University of Bern, Bremgartenstrasse 109a, CH-3012 Bern, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Esther","family":"Rothenanger","sequence":"additional","affiliation":[{"name":"LaboRvet, Wiggermatte 16, CH-6260 Reiden, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0946-8510","authenticated-orcid":false,"given":"J\u00fcrg","family":"H\u00fcsler","sequence":"additional","affiliation":[{"name":"Institute of Mathematical Statistics and Actuarial Science, University of Bern, Sidlerstrasse 5, CH-3012 Bern, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2415-3768","authenticated-orcid":false,"given":"Adrian","family":"Steiner","sequence":"additional","affiliation":[{"name":"Clinic for Ruminants, Vetsuisse Faculty, University of Bern, Bremgartenstrasse 109a, CH-3012 Bern, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5158-8906","authenticated-orcid":false,"given":"Gaby","family":"Hirsbrunner","sequence":"additional","affiliation":[{"name":"Clinic for Ruminants, Vetsuisse Faculty, University of Bern, Bremgartenstrasse 109a, CH-3012 Bern, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,3,30]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/S0739-7240(02)00154-6","article-title":"Ovarian follicular cysts in dairy cows: An abnormality in folliculogenesis","volume":"23","author":"Silvia","year":"2002","journal-title":"Domest. 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