{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:14:41Z","timestamp":1760058881001,"version":"build-2065373602"},"reference-count":37,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2025,5,2]],"date-time":"2025-05-02T00:00:00Z","timestamp":1746144000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animals"],"abstract":"<jats:p>To compare the use of postoperative analgesia for mastectomy, 44 dogs were randomly allocated to either the Splash treatment group (group A) or the Transverse Abdominis Plane block treatment group (TAP, group B). Following intramuscular (IM) premedication with pethidine (4 mg kg\u22121) and acepromazine (0.01 mg kg\u22121), anesthesia was induced with intravenous (IV) propofol and maintained with isoflurane by an anesthetist (DC) who was unaware of the treatment. In group A, ropivacaine 0.5% (2 mg kg\u22121) was administered prior to surgical wound closure. In group B, ropivacaine 0.5% (0.8\u20131 mg kg\u22121 per point) was administered by ultrasound-guided TAP block with two injection points per treated body side. At the end of the surgery, all dogs received pethidine (4 mg kg\u22121 IM), meloxicam (0.2 mg kg\u22121 IV), and acepromazine (0.005 mg kg\u22121 IV). The animals\u2019 pain was assessed by the anesthetist, who remained unaware of the treatment type used, via the Short Form of the Glasgow Composite Pain Scale. When the pain scores were \u22656, methadone (0.2 mg kg\u22121 IV) and gabapentin (10 mg kg\u22121 per oral) were started. When the pain score remained \u2265 6, ketamine (1 mg kg\u22121 subcutaneously) was administered. The dogs in the TAP block group had lower postoperative pain scores 3\u201312 h after anesthesia administration was terminated and required significantly less rescue analgesia.<\/jats:p>","DOI":"10.3390\/ani15091323","type":"journal-article","created":{"date-parts":[[2025,5,2]],"date-time":"2025-05-02T11:35:13Z","timestamp":1746185713000},"page":"1323","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Comparing the Use of Transverse Abdominis Plane Block and Splash Block for Postoperative Pain Control in Dogs Undergoing Mastectomy\u2014A Blinded Randomized Prospective Clinical Study"],"prefix":"10.3390","volume":"15","author":[{"given":"Daniele","family":"Corona","sequence":"first","affiliation":[{"name":"Department of Clinical Diagnostics and Services, Section of Anaesthesiology, Vetsuisse Faculty, University of Zurich, 8057 Zurich, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simone K.","family":"Ringer","sequence":"additional","affiliation":[{"name":"Department of Clinical Diagnostics and Services, Section of Anaesthesiology, Vetsuisse Faculty, University of Zurich, 8057 Zurich, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefanie","family":"Keller","sequence":"additional","affiliation":[{"name":"Clinic for Animal Reproduction Medicine, Vetsuisse Faculty, University of Zurich, 8057 Zurich, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7762-1217","authenticated-orcid":false,"given":"Iris M.","family":"Reichler","sequence":"additional","affiliation":[{"name":"Clinic for Animal Reproduction Medicine, Vetsuisse Faculty, University of Zurich, 8057 Zurich, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6259-9678","authenticated-orcid":false,"given":"Regula","family":"Bettschart-Wolfensberger","sequence":"additional","affiliation":[{"name":"Department of Clinical Diagnostics and Services, Section of Anaesthesiology, Vetsuisse Faculty, University of Zurich, 8057 Zurich, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2434-0141","authenticated-orcid":false,"given":"Annette P. N.","family":"Kutter","sequence":"additional","affiliation":[{"name":"Department of Clinical Diagnostics and Services, Section of Anaesthesiology, Vetsuisse Faculty, University of Zurich, 8057 Zurich, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,5,2]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Salas, Y., M\u00e1rquez, A., Diaz, D., and Romero, L. (2015). Epidemiological study of mammary tumors in female dogs diagnosed during the period 2002\u20132012: A growing animal health problem. PLoS ONE, 10.","DOI":"10.1371\/journal.pone.0127381"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1111\/j.1748-5827.2002.tb00066.x","article-title":"Canine neoplasia in the UK: Estimates of incidence rates from a population of insured dogs","volume":"43","author":"Dobson","year":"2002","journal-title":"J. Small Anim. 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