{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T17:09:39Z","timestamp":1789578579614,"version":"build-2803163510"},"reference-count":208,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2025,5,8]],"date-time":"2025-05-08T00:00:00Z","timestamp":1746662400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animals"],"abstract":"<jats:p>Plants and plant-derived natural products have been used in traditional medicine for centuries. The lack of effective therapies in the modern world to address several diseases, the increasing development of drug resistance, and the growing interest in herbal medicine have led to the study and resurgence of natural ancient remedies. A. annua, commonly known as sweet wormwood or sweet annie, is a medicinal plant widely known for its antimalarial properties. In the past decade, increasing evidence has demonstrated the plant\u2019s broad therapeutic potential, including antitumoral, antimicrobial, antiparasitic, metabolic, and immunomodulatory effects, among others. While most research has focused on human health, there is growing interest in exploring the veterinary applications of A. annua and its bioactive compounds, particularly artemisinin. This review aims to summarize the current knowledge on the beneficial effects of A. annua, artemisinin, and other compounds in animal health. It also highlights the need for standardizing A. annua metabolites to ensure the reliability and efficacy of treatments and explores how artemisinin works in synergy with other molecules present in A. annua.<\/jats:p>","DOI":"10.3390\/ani15101359","type":"journal-article","created":{"date-parts":[[2025,5,8]],"date-time":"2025-05-08T06:47:15Z","timestamp":1746686835000},"page":"1359","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["The Beneficial Use of Artemisia annua, Artemisinin, and Other Compounds in Animal Health"],"prefix":"10.3390","volume":"15","author":[{"given":"Estefania","family":"Morua","sequence":"first","affiliation":[{"name":"R&D Department, Biotech Tricopharming Research SL, Carrer Pallars 108, 08018 Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4981-0851","authenticated-orcid":false,"given":"Laura","family":"Cuyas","sequence":"additional","affiliation":[{"name":"R&D Department, Biotech Tricopharming Research SL, Carrer Pallars 108, 08018 Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5626-9576","authenticated-orcid":false,"given":"Luis","family":"Mat\u00edas-Hern\u00e1ndez","sequence":"additional","affiliation":[{"name":"R&D Department, Biotech Tricopharming Research SL, Carrer Pallars 108, 08018 Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,5,8]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1055\/a-1345-9528","article-title":"Artemisia annua\u2014Importance in Traditional Medicine and Current State of Knowledge on the Chemistry, Biological Activity and Possible Applications","volume":"87","author":"Ekiert","year":"2021","journal-title":"Planta Med."},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Hong Kong Baptist University, and Zhao, Z. 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