{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T16:44:18Z","timestamp":1785516258859,"version":"3.56.0"},"reference-count":54,"publisher":"MDPI AG","issue":"14","license":[{"start":{"date-parts":[[2025,7,14]],"date-time":"2025-07-14T00:00:00Z","timestamp":1752451200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"2024 Provincial Rural Revitalization Strategy Special Fund for Seed Industry Revitalization Action Project of the Department of Agriculture and Rural Affairs of Guangdong Province","award":["2024-XJS-00-001"],"award-info":[{"award-number":["2024-XJS-00-001"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animals"],"abstract":"<jats:p>This study evaluated the effects of Yupingfeng polysaccharides (YPF-P) on production performance, immune response, and intestinal health in goslings. A total of 240 one-day-old healthy male goslings were randomly assigned to four groups, each with six replicates of ten goslings. The Control group (Control) was fed a basal diet, while the experimental groups received the basal diet supplemented with 200 mg\/kg (YPFPI), 400 mg\/kg (YPFPII), and 600 mg\/kg (YPFPIII) of YPF-P. The results demonstrated that supplementation with 400 mg\/kg of YPF-P significantly decreased the final body weight at 21 days and the feed conversion ratio (FCR) from days 1 to 14 (p &lt; 0.05). Plasma activities of glutathione peroxidase (GSH-Px) and superoxide dismutase (SOD) were significantly elevated, while malondialdehyde (MDA) levels were reduced in the 400 and 600 mg\/kg groups (p &lt; 0.05). Both dosages significantly increased thymus and bursa of Fabricius indices, as well as plasma IL-1\u03b2 concentration (p &lt; 0.05), with IL-6 levels further elevated in the 600 mg\/kg group (p &lt; 0.05). Duodenal and ileal villus height and the villus height to crypt depth ratio were significantly improved in the 400 and 600 mg\/kg groups (p &lt; 0.05). In the cecum, acetate and isobutyrate concentrations were increased in the 400 and 600 mg\/kg groups, while propionate concentration was significantly higher in the 600 mg\/kg group (p &lt; 0.05). The 600 mg\/kg group also exhibited a significant increase in the relative abundance of beneficial bacteria such as Akkermansia and Alistipes, alongside a marked reduction in harmful pathogens, including Rickettsia (p &lt; 0.05). In summary, dietary supplementation with YPF-P enhanced antioxidant capacity, immune response, and gut microbiota composition in goslings, with the most pronounced effects observed at 600 mg\/kg.<\/jats:p>","DOI":"10.3390\/ani15142077","type":"journal-article","created":{"date-parts":[[2025,7,14]],"date-time":"2025-07-14T10:55:41Z","timestamp":1752490541000},"page":"2077","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["The Effect of Yupingfeng Polysaccharides on Immune Performance and Intestinal Microbiota in Goslings"],"prefix":"10.3390","volume":"15","author":[{"given":"Qinxin","family":"He","sequence":"first","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding, School of Animal Science and Technology, Foshan University, Foshan 528225, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miaoxin","family":"Huang","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding, School of Animal Science and Technology, Foshan University, Foshan 528225, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianyu","family":"Wang","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding, School of Animal Science and Technology, Foshan University, Foshan 528225, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Gong","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding, School of Animal Science and Technology, Foshan University, Foshan 528225, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zheng","family":"Ma","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding, School of Animal Science and Technology, Foshan University, Foshan 528225, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6077-0969","authenticated-orcid":false,"given":"Fei","family":"Ye","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding, School of Animal Science and Technology, Foshan University, Foshan 528225, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hua","family":"Li","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding, School of Animal Science and Technology, Foshan University, Foshan 528225, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,7,14]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"111825","DOI":"10.1016\/j.ecoenv.2020.111825","article-title":"Synergistic use of florfenicol and Salvia miltiorrhiza polysaccharide can enhance immune responses in broilers","volume":"210","author":"Han","year":"2021","journal-title":"Ecotoxicol. 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