{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T14:00:14Z","timestamp":1788184814934,"version":"build-2803163510"},"reference-count":65,"publisher":"MDPI AG","issue":"19","license":[{"start":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T00:00:00Z","timestamp":1759017600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100009110","name":"Natural Science Foundation of Xinjiang Uygur Autonomous Region","doi-asserted-by":"publisher","award":["2022D01A169"],"award-info":[{"award-number":["2022D01A169"]}],"id":[{"id":"10.13039\/100009110","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Special National Key Research and Development Plan","award":["2022YFD1600103"],"award-info":[{"award-number":["2022YFD1600103"]}]},{"name":"Key Research and Development Special Program of the Autonomous Region","award":["2023B02039-2"],"award-info":[{"award-number":["2023B02039-2"]}]}],"content-domain":{"domain":["www.mdpi.com"],"crossmark-restriction":true},"short-container-title":["Animals"],"abstract":"<jats:p>Plantsterol esters (PSEs) exert beneficial effects on animal product quality, indicating their potential as a nutritional intervention strategy. This study investigated the effects of dietary PSE supplementation on lactation performance and lipid metabolism in Tarim Bactrian camels (Camelus bactrianus) to establish a scientific basis for its application in their husbandry. Thirty-two mid-lactation female camels were randomly allocated to four groups (n = 8): CON (basal diet), L (200 mg\/kg PSE), M (400 mg\/kg PSE), and H (800 mg\/kg PSE). Since lactation performance is closely linked to metabolic status, biochemical and lipidomic analyses were conducted on serum and milk samples. Analysis revealed that the H group showed significantly increased milk yield, lactose yield, and milk fat yield compared to other groups. Serum cholesterol levels decreased progressively with higher PSE supplementation, while serum urea levels rose dose-dependently. Blood Glu was lower in the L group but higher in the H group relative to CON. Lipidomic profiling identified 644 and 257 differential metabolites in milk and serum, respectively. Milk metabolites were enriched in the EGFR inhibitor resistance, MAPK, and ErbB signaling pathways; serum metabolites were linked to glycerophospholipid, arachidonic acid, and linoleic acid metabolism. These findings indicate that PSE-modulated metabolites in serum and milk significantly influence lactation performance and glucolipid metabolism in Tarim Bactrian camels, supporting further investigation into precision nutrition strategies.<\/jats:p>","DOI":"10.3390\/ani15192827","type":"journal-article","created":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T11:40:52Z","timestamp":1759146052000},"page":"2827","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Lipidomics-Based Analysis of the Regulatory Effects of Phytosterol Esters on Lactation Performance and Lipid Metabolism in Tarim Bactrian camels"],"prefix":"10.3390","volume":"15","author":[{"given":"Penglan","family":"Dou","sequence":"first","affiliation":[{"name":"College of Animal Science, Xinjiang Agricultural University, Urumqi 830052, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusong","family":"Shen","sequence":"additional","affiliation":[{"name":"College of Animal Science, Xinjiang Agricultural University, Urumqi 830052, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weihua","family":"Zheng","sequence":"additional","affiliation":[{"name":"Xinjiang Academy of Agricultural Sciences, Urumqi 830091, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin","family":"Zhu","sequence":"additional","affiliation":[{"name":"College of Animal Science, Xinjiang Agricultural University, Urumqi 830052, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8818-4921","authenticated-orcid":false,"given":"Yong","family":"Chen","sequence":"additional","affiliation":[{"name":"College of Animal Science, Xinjiang Agricultural University, Urumqi 830052, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fengming","family":"Li","sequence":"additional","affiliation":[{"name":"College of Animal Science, Xinjiang Agricultural University, Urumqi 830052, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,9,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"100434","DOI":"10.1016\/j.vas.2025.100434","article-title":"Effect of a mix of condense and hydrolysable tannins feed additive on lactating dairy cows\u2019 services per conception and days open","volume":"27","author":"Castillo","year":"2025","journal-title":"Vet. Anim. Sci."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"104231","DOI":"10.1016\/j.psj.2024.104231","article-title":"Evaluation of dietary supplementation of garlic powder (Allium sativum) on the growth performance, carcass traits and meat quality of Japanese quails (Coturnix coturnix japonica)","volume":"103","author":"Jalal","year":"2024","journal-title":"Poult. Sci."},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"Abd El-Aziz, A., Elfadadny, A., Abo Ghanima, M., Cavallini, D., Fusaro, I., Giammarco, M., Buonaiuto, G., and El-Sabrout, K. (2024). Nutritional Value of Oregano-Based Products and Its Effect on Rabbit Performance and Health. Animals, 14.","DOI":"10.3390\/ani14203021"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"e31345","DOI":"10.1016\/j.heliyon.2024.e31345","article-title":"Assessing the effectiveness of cannabidiol additive supplementation on canine behavior and cortisol levels","volume":"10","author":"Marliani","year":"2024","journal-title":"Heliyon"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1002\/mnfr.201100722","article-title":"Effects of plant sterols and stanols on intestinal cholesterol metabolism: Suggested mechanisms from past to present","volume":"56","author":"Smet","year":"2012","journal-title":"Mol. Nutr. Food Res."},{"key":"ref_6","first-page":"1","article-title":"The property and function of phytosterols and their application in animal production","volume":"39","author":"Tian","year":"2018","journal-title":"Feed Ind."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"3869","DOI":"10.4238\/2014.May.16.12","article-title":"Effect of phytosterols on rumen fermentation in vitro","volume":"13","author":"Xi","year":"2014","journal-title":"Genet. Mol. Res."},{"key":"ref_8","doi-asserted-by":"crossref","unstructured":"Lv, D., Gao, J., Wu, Z., Sun, Z., Hao, L., Liu, S., Tan, Z., Cheng, Y., and Zhu, W. (2022). Multiomic Analyses Reveal the Effects of Supplementing Phytosterols on the Metabolic Function of the Rumen Microbiota in Perinatal Cows. Appl. Environ. Microbiol., 88.","DOI":"10.1128\/aem.00992-22"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1080\/87559120802682797","article-title":"Phytosterol Oxidation Products: Their Formation, Occurrence, and Biological Effects","volume":"25","author":"Ryan","year":"2009","journal-title":"Food Rev. Int."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"4629","DOI":"10.1002\/jsfa.8333","article-title":"Phytosterols on growth performance, antioxidant enzymes and intestinal morphology in weaned piglets","volume":"97","author":"Hu","year":"2017","journal-title":"J. Sci. Food Agric."},{"key":"ref_11","doi-asserted-by":"crossref","unstructured":"Shen, M., Yuan, L., Zhang, J., Wang, X., Zhang, M., Li, H., Jing, Y., Zeng, F., and Xie, J. (2024). Phytosterols: Physiological Functions and Potential Application. Foods, 13.","DOI":"10.3390\/foods13111754"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"12375","DOI":"10.1021\/jf2034237","article-title":"Chemoenzymatic synthesis of phytosteryl ferulates and evaluation of their antioxidant activity","volume":"59","author":"Tan","year":"2011","journal-title":"J. Agric. Food Chem."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1002\/ejlt.201400597","article-title":"Lipophilization of phenolic acids with phytosterols by a chemoenzymatic method to improve their antioxidant activities","volume":"117","author":"Wang","year":"2015","journal-title":"Eur. J. Lipid Sci. Technol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1039\/C9FO01570A","article-title":"The regulatory effects of phytosterol esters (PSEs on gut flora and faecal metabolites in rats with NAFLD","volume":"11","author":"Song","year":"2019","journal-title":"Food Funct."},{"key":"ref_15","first-page":"135","article-title":"Effect of maternal dietary supplementation with phytosterol esters on muscle development of broiler offspring","volume":"67","author":"Wang","year":"2020","journal-title":"Acta Biochim. Pol."},{"key":"ref_16","first-page":"346","article-title":"Research Progresses on Nutritional Components and Authenticity Identification of Camel Milk","volume":"46","author":"Li","year":"2025","journal-title":"Food Sci."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"s75","DOI":"10.1017\/S175173111800349X","article-title":"Review: Metabolic challenges in lactating dairy cows and their assessment via established and novel indicators in milk","volume":"13","author":"Gross","year":"2019","journal-title":"Animal"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.3168\/jds.S0022-0302(06)72192-0","article-title":"Major Advances Associated with the Biosynthesis of Milk","volume":"89","author":"Bauman","year":"2006","journal-title":"J. Dairy Sci."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/S0169-409X(03)00033-4","article-title":"Mammary physiology and milk secretion","volume":"55","author":"McManaman","year":"2003","journal-title":"Adv. Drug Deliv. Rev."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"231","DOI":"10.6000\/1927-5129.2016.12.35","article-title":"Physico-Chemical Analysis and Composition of Camel Milk of Bangladesh","volume":"12","author":"Mohammad","year":"2016","journal-title":"J. Basic Appl. Sci."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"105790","DOI":"10.1016\/j.idairyj.2023.105790","article-title":"Physicochemical and nutritional properties of different non-bovine milk and dairy products: A review","volume":"148","author":"Zannou","year":"2024","journal-title":"Int. Dairy J."},{"key":"ref_22","doi-asserted-by":"crossref","unstructured":"Maryam, A., and Alyaa, F. (2024). Impact of cow, buffalo, goat or camel milk consumption on oxidative stress, inflammation and immune response post weaning time. Sci. Rep., 14.","DOI":"10.1038\/s41598-024-59959-8"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.sjbs.2010.02.010","article-title":"Antigenotoxic and anticytotoxic effect of camel milk in mice treated with cisplatin","volume":"17","author":"Salwa","year":"2010","journal-title":"Saudi J. Biol. Sci."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.jfca.2008.09.008","article-title":"The composition of camel milk: A meta-analysis of the literature data","volume":"22","author":"Konuspayeva","year":"2009","journal-title":"J. Food Compos. Anal."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.foodchem.2011.03.033","article-title":"Corrigendum to \u201cComparison and characterization of fat and protein composition for camel milk from eight Jordanian locations\u201d (Food Chemistry 127 (2011) 282\u2013289)","volume":"128","author":"Ereifej","year":"2011","journal-title":"Food Chem."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"3080","DOI":"10.1080\/87559129.2021.2008953","article-title":"A comprehensive review on health benefits, nutritional composition and processed products of camel milk","volume":"39","author":"Muthukumaran","year":"2023","journal-title":"Food Rev. Int."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1016\/j.lwt.2016.11.013","article-title":"Monitoring of mild heat treatment of camel milk by front-face fluorescence spectroscopy","volume":"79","author":"Kamal","year":"2017","journal-title":"LWT Food Sci. Technol."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"3164","DOI":"10.5455\/OVJ.2024.v14.i12.2","article-title":"Camel milk: Nutritional composition, therapeutic properties, and benefits for human health","volume":"14","author":"Alhassani","year":"2024","journal-title":"Open Vet. J."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1021\/pr501305g","article-title":"Metabolomics of four biofluids from dairy cows: Potential biomarkers for milk production and quality","volume":"14","author":"Sun","year":"2015","journal-title":"J. Proteome Res."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.aca.2020.09.060","article-title":"Recent advances in analytical strategies for mass spectrometry-based lipidomics","volume":"1137","author":"Xu","year":"2020","journal-title":"Anal. Chim. Acta"},{"key":"ref_31","doi-asserted-by":"crossref","unstructured":"Fusaro, I., Parrillo, S., Buonaiuto, G., Prasinou, P., Gramenzi, A., Bucci, R., Cavallini, D., Carosi, A., Carluccio, A., and De Amicis, I. (2025). Effects of hemp-based polyunsaturated fatty acid supplementation on membrane lipid profiles and reproductive performance in Martina Franca jacks. Front. Vet. Sci., 12.","DOI":"10.3389\/fvets.2025.1553218"},{"key":"ref_32","unstructured":"(2016). National Food Safety Standard Determination of Moisture in Foods. Standard No. GB 5009.3-2016."},{"key":"ref_33","unstructured":"(2016). National Food Safety Standard Determination of Protein in Foods. Standard No. GB 5009.5-2016."},{"key":"ref_34","unstructured":"(2016). National Food Safety Standard Determination of Fat in Foods. Standard No. GB 5009.6-2016."},{"key":"ref_35","unstructured":"(2016). National Food Safety Standard Determination of Fructose, Glucose, Sucrose, Maltose, and Lactose in Foods. Standard No. GB 5009.8-2016."},{"key":"ref_36","unstructured":"(2010). National Food Safety Standard\u2014Determination of Milk Solids-Not-Fat in Milk and Milk Products. Standard No. GB 5413.39-2010."},{"key":"ref_37","first-page":"52","article-title":"The Analysis of Chemical Composition and Physico-chemical Indexes of the Junggar Bactrian Camel Milk","volume":"8","author":"Zhang","year":"2016","journal-title":"China Dairy"},{"key":"ref_38","first-page":"13","article-title":"Effects of dietary Phytosterols on milk yield and composition in dairy cows","volume":"42","author":"Lv","year":"2010","journal-title":"Anim. Husb. Vet. Med."},{"key":"ref_39","unstructured":"Jin, Z. (2010). Application of Phytosterolsnd Its Mechanisms in Dairy Cows. [Master\u2019s Thesis, Nanjing Agricultural University]."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/0024-3205(95)00263-6","article-title":"Dietary phytosterols: A review of metabolism, benefits and side effects","volume":"57","author":"Ling","year":"1995","journal-title":"Life Sci."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1006\/taap.1996.0046","article-title":"Wood-derived estrogens: Studies in vitro with breast cancer cell lines and in vivo in trout","volume":"136","author":"Mellanen","year":"1996","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"ref_42","first-page":"2732","article-title":"Effects of Different Yeast Cultures on Performance, Nutrient Apparent Digestibility and Serum Indexes of Dairy Cows in Mid-and Late-Lactation","volume":"30","author":"Yan","year":"2018","journal-title":"Chin. J. Anim. Nutr."},{"key":"ref_43","first-page":"360","article-title":"Research Progress on the Mechanisms by Which Phytosterols Influence Cholesterol Metabolism","volume":"35","author":"Chen","year":"2008","journal-title":"J. Environ. Hyg."},{"key":"ref_44","doi-asserted-by":"crossref","unstructured":"Wu, W., Ma, X., Chen, R., Fan, J., Ye, W., Chen, Z., Huang, Q., and Qian, L. (2024). Effects of Phytosterol Ester Supplementation on Egg Characteristics, Eggshell Ultrastructure, Antioxidant Capacity, Liver Function and Hepatic Metabolites of Laying Hens during Peak Laying Period. Antioxidants, 13.","DOI":"10.3390\/antiox13040458"},{"key":"ref_45","first-page":"26","article-title":"Effect of different levels of esterified phytosterols on growth performance, immune function and serum biochemical indexes of piglets","volume":"46","author":"Xia","year":"2023","journal-title":"Feed Res."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1089\/jmf.2019.4468","article-title":"Effects of Phytosterol Ester on the Fatty Acid Profiles in Rats with Nonalcoholic Fatty Liver Disease","volume":"23","author":"Song","year":"2020","journal-title":"J. Med. Food"},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"104984","DOI":"10.1016\/j.phrs.2020.104984","article-title":"Molecular mechanisms of hepatic insulin resistance in nonalcoholic fatty liver disease and potential treatment strategies","volume":"159","author":"Zhang","year":"2020","journal-title":"Pharmacol. Res."},{"key":"ref_48","first-page":"127","article-title":"Effect of Phytosterol Esters on Selected Serum Metabolites of Rats with Non-alcoholic Fatty Liver Disease(NAFLD)","volume":"41","author":"Ouyang","year":"2020","journal-title":"Food Sci."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1016\/j.foodchem.2018.11.020","article-title":"Dietary oils modify lipid molecules and nutritional value of fillet in Nile tilapia: A deep lipidomics analysis","volume":"277","author":"Liu","year":"2019","journal-title":"Food Chem."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"111305","DOI":"10.1016\/j.foodres.2022.111305","article-title":"Impact of different dietary regimens on the lipidomic profile of mare\u2019s milk","volume":"156","author":"Deng","year":"2022","journal-title":"Food Res. Int."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"1880","DOI":"10.1002\/ejlt.201500489","article-title":"Diacylglycerol-enriched oil production using chemical glycerolysis","volume":"118","author":"Satriana","year":"2016","journal-title":"Eur. J. Lipid Sci. Technol."},{"key":"ref_52","unstructured":"Wang, F. (2013). Effects of 1,3-Diacylglycerol Milk Fat on Lipid Metabolism in SD Rats and Its Underlying Mechanisms. [Master\u2019s Thesis, Anhui Agricultural University]."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.plefa.2015.07.004","article-title":"Relevance of dietary glycerophospholipids and sphingolipids to human health","volume":"101","author":"Visioli","year":"2015","journal-title":"Prostaglandins Leukot. Essent. Fat. Acids PLEFA"},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"1558","DOI":"10.1016\/j.bbamem.2017.04.006","article-title":"The critical role of phosphatidylcholine and phosphatidylethanolamine metabolism in health and disease","volume":"1859","author":"Kennelly","year":"2017","journal-title":"BBA Biomembr."},{"key":"ref_55","doi-asserted-by":"crossref","unstructured":"Barron, K., Ogretmen, B., and Krupenko, N. (2021). Dietary Folic Acid Alters Metabolism of Multiple Vitamins in a CerS6- and Sex-Dependent Manner. Front. Nutr., 8.","DOI":"10.3389\/fnut.2021.758403"},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"3854","DOI":"10.1039\/C6FO00274A","article-title":"The dietary effect of milk sphingomyelin on the lipid metabolism of obese\/diabetic KK-A(y) mice and wild-type C57BL\/6J mice","volume":"7","author":"Yamauchi","year":"2016","journal-title":"Food Funct."},{"key":"ref_57","doi-asserted-by":"crossref","unstructured":"Ganeshalingam, M., Cheema, S., Wagner, C.L., Pham, T.H., Enstad, S., Andrews, C., Grapov, D., Esposito, F., Sen, S., and Thomas, R. (2024). Exploring the impacts of human breast milk functional lipidome on infant health and growth outcomes in early life using lipid bioinformatics. bioRxiv.","DOI":"10.1101\/2024.07.25.605136"},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"8213","DOI":"10.1021\/acs.jafc.1c02035","article-title":"Relationship between Micromolecules and Quality Changes of Tilapia Fillets after Partial Freezing Treatment with Polyphenols","volume":"69","author":"Wei","year":"2021","journal-title":"J. Agric. Food Chem."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"117443","DOI":"10.1016\/j.lfs.2020.117443","article-title":"The mechanisms of lysophosphatidylcholine in the development of diseases","volume":"247","author":"Liu","year":"2020","journal-title":"Life Sci."},{"key":"ref_60","unstructured":"Li, Z. (2014). Insights into the Role of Choline Kinase in Endochondral Bone Formation and Human Osteoblasts Function. [Ph.D. Thesis, University of Alberta]."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1042\/BJ20080709","article-title":"Structure, mechanism and regulation of pyruvate carboxylase","volume":"413","author":"Jitrapakdee","year":"2008","journal-title":"Biochem. J."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1194\/jlr.R700019-JLR200","article-title":"Thematic Review Series: Glycerolipids. Phosphatidylcholine and choline homeostasis","volume":"49","author":"Li","year":"2008","journal-title":"J. Lipid Res."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"27871","DOI":"10.1074\/jbc.M801463200","article-title":"Lysobisphosphatidic acid controls endosomal cholesterol levels","volume":"283","author":"Chevallier","year":"2008","journal-title":"J. Biol. Chem."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"749","DOI":"10.3168\/jds.2007-0265","article-title":"Principal component and multivariate analysis of milk long-chain fatty acid composition during diet-induced milk fat depression","volume":"91","author":"Kadegowda","year":"2008","journal-title":"J. Dairy Sci."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1007\/s10911-021-09491-6","article-title":"A Comparative Review of the Extrinsic and Intrinsic Factors Regulating Lactose Synthesis","volume":"26","author":"Sadovnikova","year":"2021","journal-title":"J. Mammary Gland. Biol. Neoplasia"}],"container-title":["Animals"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2076-2615\/15\/19\/2827\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T12:08:43Z","timestamp":1759147723000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2076-2615\/15\/19\/2827"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,28]]},"references-count":65,"journal-issue":{"issue":"19","published-online":{"date-parts":[[2025,10]]}},"alternative-id":["ani15192827"],"URL":"https:\/\/doi.org\/10.3390\/ani15192827","relation":{},"ISSN":["2076-2615"],"issn-type":[{"value":"2076-2615","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,9,28]]}}}