{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T00:09:48Z","timestamp":1759190988043,"version":"3.44.0"},"reference-count":20,"publisher":"MDPI AG","issue":"19","license":[{"start":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T00:00:00Z","timestamp":1759017600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.mdpi.com"],"crossmark-restriction":true},"short-container-title":["Animals"],"abstract":"<jats:p>A Labrador Retriever (4-year-old, castrated male) with signs of fatigue was diagnosed with an atrial septal defect at his primary veterinary clinic. Due to the uncertainty of this diagnosis, he was referred to the Tokyo University of Agriculture and Technology Animal Medical Center for further investigation. Transthoracic echocardiography performed on arrival showed an irregular blood flow from the left atrium (LA) to the right atrium (RA), yet no opening was found in the septum. An electrocardiogram (ECG)-gated computed tomography (CT) exam revealed a communication between the coronary sinus (CS) and the LA, causing a shunt between the LA and the RA. A diagnosis of unroofed coronary sinus syndrome (UCSS) was made. The dog\u2019s condition was stable and plans to keep observations were made. This is the first case of UCSS diagnosed with an ECG-gated CT exam.<\/jats:p>","DOI":"10.3390\/ani15192834","type":"journal-article","created":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T11:40:52Z","timestamp":1759146052000},"page":"2834","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Unroofed Coronary Sinus in a Dog: Diagnostic Utility of ECG-Gated Computed Tomography"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-6204-8526","authenticated-orcid":false,"given":"Nanaha","family":"Ito","sequence":"first","affiliation":[{"name":"Laboratory of Veterinary Clinical Oncology, Faculty of Veterinary Medicine, Tokyo University of Agriculture and Technology, Tokyo 183-8509, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Risa","family":"Okamoto","sequence":"additional","affiliation":[{"name":"Animal Medical Center, Tokyo University of Agriculture and Technology, Tokyo 183-8509, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2514-695X","authenticated-orcid":false,"given":"Kazumi","family":"Shimada","sequence":"additional","affiliation":[{"name":"Laboratory of Veterinary Surgery, Faculty of Veterinary Medicine, Tokyo University of Agriculture and Technology, Tokyo 183-8509, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4512-8599","authenticated-orcid":false,"given":"Daigo","family":"Azakami","sequence":"additional","affiliation":[{"name":"Laboratory of Veterinary Clinical Oncology, Faculty of Veterinary Medicine, Tokyo University of Agriculture and Technology, Tokyo 183-8509, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9836-0749","authenticated-orcid":false,"given":"Zeki","family":"Yilmaz","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Faculty of Veterinary Medicine, Uludag University, Bursa 16059, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9948-6490","authenticated-orcid":false,"given":"Ryou","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Animal Medical Center, Tokyo University of Agriculture and Technology, Tokyo 183-8509, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5291-925X","authenticated-orcid":false,"given":"Lina","family":"Hamabe","sequence":"additional","affiliation":[{"name":"Laboratory of Veterinary Clinical Oncology, Faculty of Veterinary Medicine, Tokyo University of Agriculture and Technology, Tokyo 183-8509, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,9,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1016\/0735-1097(94)00475-6","article-title":"Unroofed coronary sinus and coronary sinus orifice atresia. Implications for management of complex congenital heart disease","volume":"25","author":"Adatia","year":"1995","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"64","DOI":"10.4103\/apc.APC_119_18","article-title":"Unroofed coronary sinus: An unusual interatrial communication and a rare childhood entity","volume":"12","author":"Murli","year":"2019","journal-title":"Ann. Pediatr. Cardiol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1655","DOI":"10.1016\/S0022-5223(03)01019-5","article-title":"Unroofed coronary sinus syndrome: Diagnosis, classification, and surgical treatment","volume":"126","author":"Ootaki","year":"2003","journal-title":"J. Thorac. Cardiovasc. Surg."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1161\/01.CIR.33.2.317","article-title":"Congenital anomalies involving the coronary sinus","volume":"33","author":"Mantini","year":"1966","journal-title":"Circulation"},{"key":"ref_5","doi-asserted-by":"crossref","unstructured":"Choi, Y., Yoon, W., Park, B.Y., Jang, Y.J., Lee, K., and Yoon, H. (2025). Case Report: A rare case of asymptomatic unroofed coronary sinus in a dog: Diagnostic imaging and genetic findings. Front. Vet. Sci., 12.","DOI":"10.3389\/fvets.2025.1611021"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jvc.2023.04.006","article-title":"Surgical repair of an unroofed coronary sinus in a dog","volume":"48","author":"Shin","year":"2023","journal-title":"J. Vet. Cardiol."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.jvc.2014.03.003","article-title":"Persistent left cranial vena cava draining into the left atrium associated with pulmonary stenosis in a French bulldog","volume":"16","author":"Zani","year":"2014","journal-title":"J. Vet. Cardiol."},{"key":"ref_8","doi-asserted-by":"crossref","unstructured":"Ma, J., Zheng, Y., Xu, S., Teng, H., Lv, L., Li, Y., Liang, Y., and Zhang, Y. (2022). The value of cardiac CT in the diagnosis of unroofed coronary sinus syndrome. BMC Cardiovasc. Disord., 22.","DOI":"10.1186\/s12872-022-02966-2"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.ijcac.2016.09.001","article-title":"The use of agitated saline in a patient with unroofed coronary sinus","volume":"2","author":"Yasar","year":"2016","journal-title":"Int. J. Cardiovasc. Acad."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"826073","DOI":"10.5402\/2013\/826073","article-title":"The Role of ECG-Gated CT in Patients with Bicuspid Aortic Valve Replacement: New Perspectives in Short- and Long-Term Followup","volume":"2013","author":"Sperandio","year":"2013","journal-title":"ISRN Radiol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1016\/j.jvc.2016.08.003","article-title":"Use of ECG-gated computed tomography, echocardiography and selective angiography in five dogs with pulmonic stenosis and one dog with pulmonic stenosis and aberrant coronary arteries","volume":"18","author":"Pedro","year":"2016","journal-title":"J. Vet. Cardiol."},{"key":"ref_12","first-page":"331","article-title":"Unroofed coronary sinus defect","volume":"14","author":"Kwok","year":"2008","journal-title":"Hong Kong Med. J."},{"key":"ref_13","first-page":"1296","article-title":"Unroofed coronary sinus: A case vignette emphasizing the role of three-dimensional transesophageal echocardiogram","volume":"81","author":"Sonsoz","year":"2023","journal-title":"Kardiol. Pol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"790715","DOI":"10.1155\/2009\/790715","article-title":"Coronary sinus to left atrial communication","volume":"2009","author":"Scheller","year":"2009","journal-title":"Case Rep. Med."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"W331","DOI":"10.2214\/AJR.09.3689","article-title":"Partially unroofed coronary sinus: MDCT and MRI findings","volume":"195","author":"Kim","year":"2010","journal-title":"AJR Am. J. Roentgenol."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"1592","DOI":"10.12998\/wjcc.v10.i5.1592","article-title":"Misdiagnosis of unroofed coronary sinus syndrome as an ostium primum atrial septal defect by echocardiography: A case report","volume":"10","author":"Chen","year":"2022","journal-title":"World J. Clin. Cases"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.jvc.2017.10.004","article-title":"Comparative anatomy and angiography of the cardiac coronary venous system in four species: Human, ovine, porcine, and canine","volume":"20","author":"Genain","year":"2018","journal-title":"J. Vet. Cardiol."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"955","DOI":"10.2214\/AJR.08.2158","article-title":"Prospective and retrospective ECG gating for thoracic CT angiography: A comparative study","volume":"193","author":"Wu","year":"2009","journal-title":"AJR Am. J. Roentgenol."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1111\/jocs.15269","article-title":"Surgical management of unroofed coronary sinus syndrome: A 20-year-single-center experience","volume":"36","author":"Shi","year":"2021","journal-title":"J. Card. Surg."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.jvc.2023.12.004","article-title":"Two- and three-dimensional transesophageal echocardiographic assessment and successful occlusion of a window-like patent ductus arteriosus in two dogs","volume":"51","author":"Craciun","year":"2024","journal-title":"J. Vet. 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