{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:30:59Z","timestamp":1787027459418,"version":"build-2736575974"},"reference-count":28,"publisher":"MDPI AG","issue":"20","license":[{"start":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T00:00:00Z","timestamp":1760313600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National Key Research and Development Program of China","award":["2022YFD1300904"],"award-info":[{"award-number":["2022YFD1300904"]}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["32072814"],"award-info":[{"award-number":["32072814"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["32072812"],"award-info":[{"award-number":["32072812"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["32072714"],"award-info":[{"award-number":["32072714"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Biological Breeding-National Science and Technology Major Project","award":["2023ZD04068"],"award-info":[{"award-number":["2023ZD04068"]}]},{"name":"Project of Guangdong Provincial Nature Science Foundation","award":["2023A1515012511"],"award-info":[{"award-number":["2023A1515012511"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animals"],"abstract":"<jats:p>This study evaluated the effects of additional L-serine supplementation in diets on performance, carcass characteristics, meat quality and small intestine development in broilers. A total of 300 one-day-old unsexed Yellow-Feathered broilers were randomly divided into three groups with 10 replicates of 10 birds each. The broilers were fed basal diet (CON), basal diet + 0.085% L-Alanine (Isonitrogenous) and basal diet + 0.1% L-serine (0.1% Ser), respectively. The whole trial lasted for 42 d. The results showed that 0.1% L-serine supplementation in broiler diets could increase final body weight and average daily weight gain (p &lt; 0.05) and had no significant effect on serum biochemical indexes (p &gt; 0.05). Compared with the Isonitrogenous group, the 0.1% Ser group significantly reduced FCR (p &lt; 0.05). Regarding meat quality, the 0.1% Ser group significantly increased by a*45 min and 24 h pH values, while it decreased by b*45 min values in both breast and leg muscles (p &lt; 0.05) and reduced cooking loss in leg muscles (p &lt; 0.05). L-serine effectively reduced localized fat deposition and promoted intestinal development. Morphometric analysis revealed significantly increased small intestinal villus length and villus length\/crypt depth ratio in the 0.1% Ser group (p &lt; 0.05). In conclusion, L-serine can be used as an effective supplement in broiler farming to improve its productivity.<\/jats:p>","DOI":"10.3390\/ani15202965","type":"journal-article","created":{"date-parts":[[2025,10,14]],"date-time":"2025-10-14T07:51:28Z","timestamp":1760428288000},"page":"2965","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Dietary Supplementation with L-Serine Regulates Growth Performance, Carcass Traits, Meat Quality, and Intestinal Development in Broilers"],"prefix":"10.3390","volume":"15","author":[{"given":"Longlong","family":"Li","sequence":"first","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Animal Nutrition Control, National Engineering Research Center for Breeding Swine Industry, College of Animal Science, South China Agricultural University, No. 483 Wushan Road, Guangzhou 510642, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei","family":"Su","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Animal Nutrition Control, National Engineering Research Center for Breeding Swine Industry, College of Animal Science, South China Agricultural University, No. 483 Wushan Road, Guangzhou 510642, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Animal Nutrition Control, National Engineering Research Center for Breeding Swine Industry, College of Animal Science, South China Agricultural University, No. 483 Wushan Road, Guangzhou 510642, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1060-4081","authenticated-orcid":false,"given":"Junyi","family":"Luo","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Animal Nutrition Control, National Engineering Research Center for Breeding Swine Industry, College of Animal Science, South China Agricultural University, No. 483 Wushan Road, Guangzhou 510642, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting","family":"Chen","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Animal Nutrition Control, National Engineering Research Center for Breeding Swine Industry, College of Animal Science, South China Agricultural University, No. 483 Wushan Road, Guangzhou 510642, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1992-154X","authenticated-orcid":false,"given":"Jiajie","family":"Sun","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Animal Nutrition Control, National Engineering Research Center for Breeding Swine Industry, College of Animal Science, South China Agricultural University, No. 483 Wushan Road, Guangzhou 510642, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongliang","family":"Zhang","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Animal Nutrition Control, National Engineering Research Center for Breeding Swine Industry, College of Animal Science, South China Agricultural University, No. 483 Wushan Road, Guangzhou 510642, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qianyun","family":"Xi","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Animal Nutrition Control, National Engineering Research Center for Breeding Swine Industry, College of Animal Science, South China Agricultural University, No. 483 Wushan Road, Guangzhou 510642, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,10,13]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Gr\u017eini\u0107, G., Piotrowicz-Cie\u015blak, A., Klimkowicz-Pawlas, A., G\u00f3rny, R.L., \u0141awniczek-Wa\u0142czyk, A., Piechowicz, L., Olkowska, E., Potrykus, M., Tankiewicz, M., and Krupka, M. 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