{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T09:00:53Z","timestamp":1764752453664,"version":"3.46.0"},"reference-count":49,"publisher":"MDPI AG","issue":"23","license":[{"start":{"date-parts":[[2025,11,30]],"date-time":"2025-11-30T00:00:00Z","timestamp":1764460800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National Council for Scientific and Technological Development (CNPq) Announcement","award":["09\/2023"],"award-info":[{"award-number":["09\/2023"]}]},{"name":"Research Productivity Grants","award":["313033\/2023-4"],"award-info":[{"award-number":["313033\/2023-4"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animals"],"abstract":"<jats:p>Quail farming necessitates the provision of balanced diets to promote avian health and performance, with dietary fiber and feed additives exerting significant influence on immune and physiological responses. This study aimed to evaluate the effects of stimbiotic inclusion in diets characterized by varying fiber profiles on hematological and biochemical parameters in European quails (Coturnix coturnix coturnix). A total of six hundred quails, aged from 1 to 35 days, were assigned to 12 distinct treatments, each comprising 5 replicates of 10 birds. The dietary treatments included a corn\u2013soy control, two basal diets featuring corn (low soluble fiber) and wheat (high soluble fiber), and three mixed diets that combined corn and wheat in varying proportions, with each diet supplemented with or without 0.01% stimbiotic. Blood samples were collected at 14 and 35 days of age. In the initial phase (1\u201314 days), the addition of stimbiotic resulted in increased hemoglobin levels and a reduction in total white blood cells, heterophils, and lymphocytes, indicative of an enhanced immune status. In contrast, dietary fiber was found to influence liver enzyme activity and triglyceride levels. During the growth phase (15\u201335 days), stimbiotic continued to exert positive effects on hemoglobin and packed cell volume, while dietary fiber increased eosinophil counts, modulating the immune response without affecting other parameters. In conclusion, dietary fiber plays a functional role, particularly during the growth phase, while stimbiotic inclusion enhances immune function in both developmental stages, demonstrating that both strategies contribute positively to the health and performance of European quails.<\/jats:p>","DOI":"10.3390\/ani15233457","type":"journal-article","created":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T08:44:28Z","timestamp":1764751468000},"page":"3457","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Hematological and Biochemical Parameters of European Quails (Coturnix coturnix coturnix) Fed Diets with Different Fiber Profiles, with and Without Stimbiotic Inclusion, from 1 to 35 Days"],"prefix":"10.3390","volume":"15","author":[{"given":"Luayne Morais","family":"Correa","sequence":"first","affiliation":[{"name":"Department of Veterinary Sciences, Center of Agricultural Sciences, Federal University of Paraiba, Areia 58397-000, Paraiba, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2796-1675","authenticated-orcid":false,"given":"Adiel Vieira de","family":"Lima","sequence":"additional","affiliation":[{"name":"Department of Animal Science, Center of Agricultural Sciences, Federal University of Paraiba, Areia 58397-000, Paraiba, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1123-086X","authenticated-orcid":false,"given":"Edijanio Galdino da","family":"Silva","sequence":"additional","affiliation":[{"name":"Department of Veterinary Sciences, Center of Agricultural Sciences, Federal University of Paraiba, Areia 58397-000, Paraiba, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7329-2989","authenticated-orcid":false,"given":"Anderson Antonio Ferreira da","family":"Silva","sequence":"additional","affiliation":[{"name":"Department of Animal Science, Center of Agricultural Sciences, Federal University of Paraiba, Areia 58397-000, Paraiba, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5287-0444","authenticated-orcid":false,"given":"Maria das Gra\u00e7as da Silva","family":"Bernardino","sequence":"additional","affiliation":[{"name":"Department of Veterinary Sciences, Center of Agricultural Sciences, Federal University of Paraiba, Areia 58397-000, Paraiba, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raiane dos Santos","family":"Silva","sequence":"additional","affiliation":[{"name":"Department of Animal Science, Center of Agricultural Sciences, Federal University of Paraiba, Areia 58397-000, Paraiba, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6410-244X","authenticated-orcid":false,"given":"Neila Lidiany","family":"Ribeiro","sequence":"additional","affiliation":[{"name":"Department of Animal Science, Center of Agricultural Sciences, Federal University of Paraiba, Areia 58397-000, Paraiba, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jammily Ketly Guedes","family":"Caetano","sequence":"additional","affiliation":[{"name":"Department of Veterinary Sciences, Center of Agricultural Sciences, Federal University of Paraiba, Areia 58397-000, Paraiba, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8442-3195","authenticated-orcid":false,"given":"Xavi\u00e8re","family":"Rousseau","sequence":"additional","affiliation":[{"name":"Ab Vista, 3 Woodstock Court, Marlborough, Wiltshire SN8 4AN, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9897-6209","authenticated-orcid":false,"given":"Matheus Ramalho de","family":"Lima","sequence":"additional","affiliation":[{"name":"Animal Science Departament, Federal University of the Semi-Arid Region, Campus Mossor\u00f3, Mossoro 59625-900, Rio Grande do Norte, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4075-1792","authenticated-orcid":false,"given":"Fernando Guilherme Perazzo","family":"Costa","sequence":"additional","affiliation":[{"name":"Department of Animal Science, Center of Agricultural Sciences, Federal University of Paraiba, Areia 58397-000, Paraiba, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ricardo Rom\u00e3o","family":"Guerra","sequence":"additional","affiliation":[{"name":"Department of Veterinary Sciences, Center of Agricultural Sciences, Federal University of Paraiba, Areia 58397-000, Paraiba, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,11,30]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Cullere, M., Woods, M.J., Van Emmenes, L., Pieterse, E., Homman, L.C., and Zotte, A.D. 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