{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,24]],"date-time":"2025-12-24T11:44:26Z","timestamp":1766576666068,"version":"3.48.0"},"reference-count":57,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2025,12,24]],"date-time":"2025-12-24T00:00:00Z","timestamp":1766534400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animals"],"abstract":"<jats:p>Canine steroid-responsive meningitis\u2013arteritis (SRMA) is a systemic, immune-mediated, inflammatory disease which occasionally leads to spontaneous haemorrhage, both within and outside the central nervous system, as a possible complication. No previous studies have investigated the haemostatic profile in a cohort of dogs with SRMA using viscoelastic monitoring. The aim of this study was to assess haemostatic function in a cohort of dogs affected by SRMA using the Entegrion VCM (Viscoelastic Coagulation Monitor) Vet\u2122 device. This was a multicentre prospective study conducted between April 2023 and April 2025 recruiting dogs with SRMA from four veterinary referral hospitals in the United Kingdom. All four research centres used the Entegrion VCM Vet\u2122 device for evaluation of haemostasis. Twenty dogs were included in the study. One dog had a hypercoagulable VCM result, and two dogs were considered hyperfibrinolytic based on their VCM results. No dogs had any clinical signs of vascular complications (ischaemic and\/or haemorrhagic stroke, haematomas, or haemorrhages). Although the pathophysiology of vascular events in dogs with SRMA remains unclear, the results of this study suggest that further investigations into the fibrinolytic system and endothelial structure in dogs affected by SRMA are warranted.<\/jats:p>","DOI":"10.3390\/ani16010050","type":"journal-article","created":{"date-parts":[[2025,12,24]],"date-time":"2025-12-24T11:22:14Z","timestamp":1766575334000},"page":"50","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["An Explorative Study of Haemostasis in Canine Steroid-Responsive Meningitis\u2013Arteritis Using Viscoelastic Monitoring"],"prefix":"10.3390","volume":"16","author":[{"given":"Kine Bergum","family":"Hjellegjerde","sequence":"first","affiliation":[{"name":"Anderson Moores Veterinary Specialists, The Granary, Bunstead Barns, Poles Lane, Hursley, Winchester SO21 2LL, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3619-4049","authenticated-orcid":false,"given":"Berry","family":"Wong","sequence":"additional","affiliation":[{"name":"Anderson Moores Veterinary Specialists, The Granary, Bunstead Barns, Poles Lane, Hursley, Winchester SO21 2LL, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0509-247X","authenticated-orcid":false,"given":"Sophie","family":"Wyatt","sequence":"additional","affiliation":[{"name":"Hawkshead Campus, The Royal Veterinary College, Hawkshead Lane, Hatfield, Hertfordshire AL9 7TA, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Scarpante","sequence":"additional","affiliation":[{"name":"Dick White Referral Veterinary Specialists, Station Farm, London Road, Six Mile Bottom, Cambridgeshire CB8 0UH, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patricia","family":"Alvarez","sequence":"additional","affiliation":[{"name":"Neurology and Neurosurgery Service, IVC Evidensia, Pride Veterinary Referrals, Riverside Rd, Derby DE24 8HX, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annette","family":"Wessmann","sequence":"additional","affiliation":[{"name":"Neurology and Neurosurgery Service, IVC Evidensia, Pride Veterinary Referrals, Riverside Rd, Derby DE24 8HX, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucy","family":"McMahon","sequence":"additional","affiliation":[{"name":"Anderson Moores Veterinary Specialists, The Granary, Bunstead Barns, Poles Lane, Hursley, Winchester SO21 2LL, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adam","family":"Mugford","sequence":"additional","affiliation":[{"name":"Hawkshead Campus, The Royal Veterinary College, Hawkshead Lane, Hatfield, Hertfordshire AL9 7TA, UK"},{"name":"Banco de Sangue Animal, Rua de Jo\u00e3o de Deus, n\u00b0741, 4100-462 Porto, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3019-1317","authenticated-orcid":false,"given":"Josep","family":"Brocal","sequence":"additional","affiliation":[{"name":"Anderson Moores Veterinary Specialists, The Granary, Bunstead Barns, Poles Lane, Hursley, Winchester SO21 2LL, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,12,24]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1111\/j.1939-1676.2009.0337.x","article-title":"Steroid responsive meningitis-arteritis: A prospective study of potential disease markers, prednisolone treatment, and long-term outcome in 20 dogs (2006\u20132008)","volume":"23","author":"Lowrie","year":"2009","journal-title":"J. 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