{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T19:44:12Z","timestamp":1774640652651,"version":"3.50.1"},"reference-count":58,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2025,12,28]],"date-time":"2025-12-28T00:00:00Z","timestamp":1766880000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"China Agriculture Research System","award":["CARS-41-13"],"award-info":[{"award-number":["CARS-41-13"]}]},{"name":"Hebei Agriculture Research System","award":["HBCT2024270204"],"award-info":[{"award-number":["HBCT2024270204"]}]},{"DOI":"10.13039\/501100003787","name":"Natural Science Foundation of Hebei Province","doi-asserted-by":"publisher","award":["C2025204113"],"award-info":[{"award-number":["C2025204113"]}],"id":[{"id":"10.13039\/501100003787","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Hebei Agricultural Science and Technology Transformation Funds"},{"name":"Hebei Provincial University Basic Scientific Research Operating Expenses Project","award":["KY2025032"],"award-info":[{"award-number":["KY2025032"]}]},{"name":"Hebei Agricultural University Talents Introduction Project","award":["YJ2024026"],"award-info":[{"award-number":["YJ2024026"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animals"],"abstract":"<jats:p>This study aimed to investigate the effects of a compound probiotic on production performance and antioxidant capacity in post-molting broiler breeders. A total of 6800 healthy 69-week-old Arbor Acres breeders were randomly allocated to 2 treatment groups (4 replicates of 850 birds each). Both groups were fed an identical basal diet, whereas the drinking water was supplemented with 75 g\/t of the compound probiotic for the Experimental group only. The trial included a 7-day adaptation followed by a 49-day experimental period. Results demonstrated that drinking water supplementation with dietary compound probiotic preparation improved the laying performance rate, fertilization rate, and hatchability compared to the control (p &lt; 0.05). The serum total antioxidant capacity was significantly enhanced (p &lt; 0.05), while a concurrent trend of reduction in MDA content was also noted (p = 0.086). Significant decreases in serum total protein and globulin levels were observed (p &lt; 0.05). Antioxidant profiles in reproductive tissues were also improved, with increased superoxide dismutase activity in the liver and oviduct, enhanced total antioxidant capacity in the ovary and oviduct, and a concurrent decrease in malondialdehyde content in the oviduct (p &lt; 0.05). Furthermore, serum immunoglobulin M, and cecal butyric acid and isobutyric acid contents were higher in the compound probiotic preparation group (p &lt; 0.05). In conclusion, supplementing drinking water with the compound probiotic during the post-molting period enhanced production performance, antioxidant status, and immune and gut health in aging broiler breeders, supporting the preservation of valuable poultry genetic resources.<\/jats:p>","DOI":"10.3390\/ani16010085","type":"journal-article","created":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T07:52:59Z","timestamp":1766994779000},"page":"85","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Compound Probiotics Enhance Performance, Antioxidant Status, and Cecal SCFAs in Post-Molting Broiler Breeders"],"prefix":"10.3390","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3557-6814","authenticated-orcid":false,"given":"Bowen","family":"Yang","sequence":"first","affiliation":[{"name":"College of Animal Science and Technology, Hebei Agricultural University, Baoding 071000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-4548-2651","authenticated-orcid":false,"given":"Yuhan","family":"Wei","sequence":"additional","affiliation":[{"name":"College of Animal Science and Technology, Hebei Agricultural University, Baoding 071000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuqing","family":"Yang","sequence":"additional","affiliation":[{"name":"College of Animal Science and Technology, Hebei North University, Zhangjiakou 075132, China"},{"name":"Hebei Institute of Animal Science and Veterinary Medicine, Baoding 071030, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Minhong","family":"Zhang","sequence":"additional","affiliation":[{"name":"Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chengmin","family":"Wang","sequence":"additional","affiliation":[{"name":"Center for Wildlife Diseases and Immunology, Institute of Zoology, Guangdong Academy of Sciences, Guangzhou 510275, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qi","family":"Wang","sequence":"additional","affiliation":[{"name":"Hebei Institute of Animal Science and Veterinary Medicine, Baoding 071030, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jue","family":"Wang","sequence":"additional","affiliation":[{"name":"Hebei Institute of Animal Science and Veterinary Medicine, Baoding 071030, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuejing","family":"Wang","sequence":"additional","affiliation":[{"name":"Hebei Institute of Animal Science and Veterinary Medicine, Baoding 071030, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Baoliang","family":"Fan","sequence":"additional","affiliation":[{"name":"College of Animal Science and Technology, Hebei Agricultural University, Baoding 071000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,12,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Ren, Q., Gong, Y., Su, P., Liu, G., Pu, Y., Yu, F., Ma, Y., Wang, Z., Li, Y., and Jiang, L. 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