{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T04:48:43Z","timestamp":1792212523909,"version":"4.4.0"},"reference-count":46,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T00:00:00Z","timestamp":1772496000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003627","name":"Rural Development Administration, Republic of Korea","doi-asserted-by":"publisher","award":["PJ01621002"],"award-info":[{"award-number":["PJ01621002"]}],"id":[{"id":"10.13039\/501100003627","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animals"],"abstract":"<jats:p>This experiment was designed to determine the effect of the Lacticaseibacillus paracasei (paracasei) strain NSMJ27, isolated from Korean fermented vegetable food (home-made kimchi), on laying performance, egg quality, intestinal histology, cecal short-chain fatty acids, and ileal antioxidant\/immunity indicators of laying hens. Ninety-six 55-week-old Hy-Line Brown hens were randomly assigned to two dietary treatments with each treatment comprising eight replicates of six hens each. Experimental diets were prepared by mixing corn and soybean meal basal diets without or with L. paracasei NSMJ27 at 2.5 \u00d7 109 CFU\/kg. The experiment lasted 4 weeks. Laying hens fed with the NSMJ27-supplemented diet were not affected (p &gt; 0.05) in their laying performance or egg quality. With respect to ileal morphology, villus height: crypt depth ratio tended to be higher (p = 0.067) in laying hens fed with L. paracasei NSMJ27 vs. control diets. Dietary L. paracasei did not affect (p &gt; 0.05) the activities of glutathione peroxidase and catalase, malondialdehyde contents, or secretory immunoglobulin A in ileal mucosa, but increased (p = 0.048) the activity of superoxide dismutase compared with the control diet-fed laying hens. Dietary L. paracasei elevated (p = 0.016) the relative percentage of butyrate but lowered (p = 0.057) that of isovalerate in cecal digesta. Dietary L. paracasei did not affect the percentages of cells expressing macrophages, B cells, CD4+ T cells, CD8+ T cells, or TCR\u03b3\u03b4 T cell surface markers (p &gt; 0.05). Overall, these results suggest that dietary L. paracasei NSMJ27 could enhance gut health via increasing gut antioxidant capacity and butyrate production in the cecal digesta of laying hens.<\/jats:p>","DOI":"10.3390\/ani16050792","type":"journal-article","created":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T16:18:45Z","timestamp":1772554725000},"page":"792","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Effects of Probiotic Lacticaseibacillus paracasei NSMJ27 on Laying Performance and Gut Health Indicators in Aged Laying Hens"],"prefix":"10.3390","volume":"16","author":[{"given":"Viet Anh","family":"Vu","sequence":"first","affiliation":[{"name":"Department of Animal Science and Technology, College of Life Sciences, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029, Republic of Korea"},{"name":"Department of Animal Breeding and Genetics, Vietnam National University of Agriculture, Hanoi 12406, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8417-6967","authenticated-orcid":false,"given":"Yoo-Bhin","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Animal Science and Technology, College of Life Sciences, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soo-Ki","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Animal Science and Technology, College of Life Sciences, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029, Republic of Korea"},{"name":"Department of Animal Breeding and Genetics, Vietnam National University of Agriculture, Hanoi 12406, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6703-3072","authenticated-orcid":false,"given":"Ji Young","family":"Jung","sequence":"additional","affiliation":[{"name":"Microbial Research Department, Nakdonggang National Institute of Biological Resources (NNIBR), 137, Donam 2-gil, Sangju 37242, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang Seok","family":"Joo","sequence":"additional","affiliation":[{"name":"Department of Animal Science, College of Natural Resource & Life Sciences, Pusan National University, Miryang 50463, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Byeongcheol","family":"Ban","sequence":"additional","affiliation":[{"name":"Department of Animal Science, College of Natural Resource & Life Sciences, Pusan National University, Miryang 50463, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Myunghoo","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Agricultural Biotechnology, Research Institute of Agriculture and Life Sciences, College of Agriculture and Life Sciences, Seoul National University, Gwanak-gu, Seoul 08826, Republic of Korea"},{"name":"The Institute of Animal Science and Technology, Research Institute of Agriculture and Life Sciences, College of Agriculture and Life Sciences, Seoul National University, Gwanak-gu, Seoul 08826, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2106-1921","authenticated-orcid":false,"given":"Minji","family":"Kim","sequence":"additional","affiliation":[{"name":"Animal Nutrition and Physiology Division, National Institute of Animal Science, Rural Development Administration (NIAS-RDA), 1500, Kongjwipatjwi-ro, Iseo-myeon, Wanju 55365, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3533-7979","authenticated-orcid":false,"given":"Kyung-Woo","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Animal Science and Technology, College of Life Sciences, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,3,3]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2052","DOI":"10.3382\/ps.2008-00091","article-title":"Factors Affecting Intestinal Health in Poultry","volume":"87","author":"Yegani","year":"2008","journal-title":"Poult. 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