{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T09:35:39Z","timestamp":1785404139909,"version":"3.56.0"},"reference-count":58,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T00:00:00Z","timestamp":1778716800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002848","name":"Agencia Nacional de Investigaci\u00f3n y Desarrollo","doi-asserted-by":"publisher","award":["11220188"],"award-info":[{"award-number":["11220188"]}],"id":[{"id":"10.13039\/501100002848","id-type":"DOI","asserted-by":"publisher"}]},{"award":["11220188"],"award-info":[{"award-number":["11220188"]}],"id":[{"id":"https:\/\/ror.org\/02ap3w078","id-type":"ROR","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animals"],"abstract":"<jats:p>Nutrient restriction (NR) increases small-for-gestational-age (SGA) offspring; however, some NR ewes deliver Non-SGA lambs. We evaluated whether fetal biometry and Doppler indices could distinguish divergent fetal growth trajectories. Ninety-five single-pregnant Corriedale ewes were assigned to NR grazing (n = 72) or supplemented Controls (n = 23) from gestational day (GD) 70 to 140. Fetal biparietal diameter (BPD), femur length (FL), thoracic height (TH), umbilical cord diameter (UCD), and resistance (RI) and pulsatility (PI) indices in umbilical (UA), cotyledonary (CA), and uterine (UtA) arteries were assessed at several GDs. Offspring within NR group was stratified by birth weight (BW) quartiles as SGA (n = 18) or Non-SGA (n = 18). At birth, BW differed (p &lt; 0.05) among Control (4.95 \u00b1 0.10 kg), Non-SGA (5.33 \u00b1 0.06 kg), and SGA (3.79 \u00b1 0.11 kg), with reduced BPD and FL in SGA lambs. Prenatal biometry did not differ. UA-RI at GD125 was higher in SGA (p &lt; 0.005) and associated with BW (R2 = 0.15; p &lt; 0.001). UtA indices were lower in SGA at GD110 and GD125 (p &lt; 0.05) but weakly associated with BW (R2 \u2264 0.08). Doppler differences were detected before measurable growth divergence but have modest predictive value.<\/jats:p>","DOI":"10.3390\/ani16101499","type":"journal-article","created":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T13:04:09Z","timestamp":1778763849000},"page":"1499","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Doppler Ultrasound Indices and Fetal Biometry as Prenatal Markers of SGA or Non-SGA Developmental Trajectories in Naturally Nutrient-Restricted Sheep Pregnancies from Patagonia"],"prefix":"10.3390","volume":"16","author":[{"given":"Mat\u00edas","family":"Araya","sequence":"first","affiliation":[{"name":"Facultad de Ciencias Veterinarias y Pecuarias, Universidad de Chile, Santiago 8820808, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9sar","family":"Ulloa-Leal","sequence":"additional","affiliation":[{"name":"Facultad de Medicina Veterinaria, Universidad San Sebasti\u00e1n, Concepci\u00f3n 4081322, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6072-7469","authenticated-orcid":false,"given":"Marcelo","family":"Ratto","sequence":"additional","affiliation":[{"name":"Facultad de Ciencias Veterinarias, Universidad Austral de Chile, Valdivia 5091000, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9197-8658","authenticated-orcid":false,"given":"Francisco","family":"Sales","sequence":"additional","affiliation":[{"name":"Instituto de Investigaciones Agropecuarias, Punta Arenas 6210489, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3621-2705","authenticated-orcid":false,"given":"V\u00edctor H.","family":"Parraguez","sequence":"additional","affiliation":[{"name":"Facultad de Ciencias Veterinarias y Pecuarias, Universidad de Chile, Santiago 8820808, Chile"},{"name":"Facultad de Ciencias Agron\u00f3micas, Universidad de Chile, Santiago 8820808, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5219-0174","authenticated-orcid":false,"given":"Camila","family":"Sandoval","sequence":"additional","affiliation":[{"name":"Facultad de Ciencias Veterinarias, Universidad de Concepci\u00f3n, Chill\u00e1n 3800708, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,5,14]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1038\/416389a","article-title":"Ecological responses to recent climate change","volume":"416","author":"Walther","year":"2002","journal-title":"Nature"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1071\/EA08033","article-title":"Climate change and Australian livestock systems: Impacts, research and policy issues","volume":"48","author":"Howden","year":"2008","journal-title":"Aust. 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