{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T05:18:04Z","timestamp":1788585484378,"version":"build-2803163510"},"reference-count":59,"publisher":"MDPI AG","issue":"17","license":[{"start":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T00:00:00Z","timestamp":1788134400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31972698"],"award-info":[{"award-number":["31972698"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"award":["31972698"],"award-info":[{"award-number":["31972698"]}],"id":[{"id":"https:\/\/ror.org\/01h0zpd94","id-type":"ROR","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012246","name":"Priority Academic Program Development of Jiangsu Higher Education Institutions","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100012246","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100013314","name":"111 Project","doi-asserted-by":"crossref","award":["D18007"],"award-info":[{"award-number":["D18007"]}],"id":[{"id":"10.13039\/501100013314","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animals"],"abstract":"<jats:p>Avian coccidiosis is an intestinal disease caused by several different Eimeria spp. that impair the host\u2019s intestinal system, resulting in poor nutrition absorption, reduced growth, and often death. Increasing evidence from recent studies indicates that Eimeria infection disrupts epithelial integrity and reshapes the intestinal microbial ecosystem. Probiotics can enhance poultry productivity and gut health by modulating the microbiome, with certain probiotics demonstrating anticoccidial properties. A detailed understanding of Eimeria-induced dysbiosis, barrier injury, mucosal inflammation, secondary bacterial risk, and probiotic-mediated control is necessary for the effective application of probiotics in commercial practice and for developing logical strategies to control coccidiosis in the post-antibiotic era. This review differs from general coccidiosis or probiotic reviews by integrating evidence across five linked dimensions: Eimeria species, intestinal site, time after infection, probiotic strain or function, and production translation. It summarizes the current understanding of Eimeria-driven gut microbiota dysbiosis and probiotic-based interventions for chicken coccidiosis, with a focus on intestinal site specificity, temporal microbial patterns, microbial metabolism, host\u2013microbiota interactions, and practical implications for poultry production. Future research should move from correlation-based microbiota profiling toward strain-resolved, mechanism-oriented, and production-relevant evaluation.<\/jats:p>","DOI":"10.3390\/ani16172703","type":"journal-article","created":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T01:05:26Z","timestamp":1788224726000},"page":"2703","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Eimeria-Induced Gut Microbiota Dysbiosis and Probiotic-Mediated Control of Chicken Coccidiosis: Recent Advances and Future Perspectives"],"prefix":"10.3390","volume":"16","author":[{"given":"Kun","family":"Xu","sequence":"first","affiliation":[{"name":"College of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China"},{"name":"College of Electrical, Energy and Power Engineering, Yangzhou University, Yangzhou 225009, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huricha","family":"Bao","sequence":"additional","affiliation":[{"name":"School of Journalism and Communication, Yangzhou University, Yangzhou 225009, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4669-9470","authenticated-orcid":false,"given":"Jianping","family":"Tao","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China"},{"name":"Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Yangzhou 225009, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2833-0178","authenticated-orcid":false,"given":"Nianyu","family":"Xue","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China"},{"name":"Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Yangzhou 225009, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,8,31]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1017\/S0031182019001562","article-title":"Life cycle stages, specific organelles and invasion mechanisms of Eimeria species","volume":"147","author":"Burrell","year":"2019","journal-title":"Parasitology"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1146\/annurev.mi.17.100163.001143","article-title":"COCCIDIOSIS","volume":"17","author":"Levine","year":"1963","journal-title":"Annu. 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