{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T10:09:03Z","timestamp":1789380543092,"version":"build-2803163510"},"reference-count":76,"publisher":"MDPI AG","issue":"18","license":[{"start":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T00:00:00Z","timestamp":1789257600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National Key Research and Development Programs of China","award":["2022YFD1300503"],"award-info":[{"award-number":["2022YFD1300503"]}]},{"name":"Guangdong Feed Industry Technology System","award":["2024CXTD14"],"award-info":[{"award-number":["2024CXTD14"]}]},{"name":"Special Fund for Scientific Innovation Strategy-Construction of High Level Academy of Agricultural Sciences","award":["202106TD"],"award-info":[{"award-number":["202106TD"]}]},{"name":"Foreign Expert Project","award":["QNL20200130001"],"award-info":[{"award-number":["QNL20200130001"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animals"],"abstract":"<jats:p>Selenium (Se) is essential in poultry nutrition for antioxidant defense through selenoproteins. While selenomethionine (Se-Met) is commonly used, L-selenomethylselenocysteine (L-SeMC) may offer more favorable responses for selected measured variables. This study compared Se-Met and L-SeMC effects on growth, antioxidant status, and meat quality in broilers. Six hundred and sixty one-day-old male Cobb 500 broiler chickens were randomly assigned to 11 dietary treatments, with six replicate pens of 10 birds per treatment, comprising a basal control diet and 10 selenium-supplemented diets arranged in a 2 \u00d7 5 factorial design (Se-Met or L-SeMC at 0.05, 0.10, 0.15, 0.20, or 0.25 mg Se\/kg) for 42 days. Selenium supplementation significantly improved average daily gain, final body weight, and feed conversion ratio (p &lt; 0.05). Model-estimated stationary points ranged from 0.137 to 0.142 mg\/kg for Se-Met and 0.080\u20130.126 mg\/kg for L-SeMC. Using source-specific model-estimated stationary points, L-SeMC showed 1.85- to 1.93-fold higher biological potency than Se-Met. Birds fed L-SeMC exhibited higher plasma glutathione peroxidase activity, lower malondialdehyde, improved meat color (higher a*_24h), higher ultimate pH, and lower drip loss (p &lt; 0.05). L-SeMC is more effective than Se-Met for enhancing broiler growth, antioxidant capacity, and meat quality.<\/jats:p>","DOI":"10.3390\/ani16182882","type":"journal-article","created":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T09:34:01Z","timestamp":1789378441000},"page":"2882","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["L-Selenomethylselenocysteine Improves Growth Performance, Antioxidant Status, and Meat Quality in White-Feathered Broilers More Effectively than Selenomethionine"],"prefix":"10.3390","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-0681-1142","authenticated-orcid":false,"given":"Xue","family":"Yang","sequence":"first","affiliation":[{"name":"State Key Laboratory of Swine and Poultry Breeding Industry, Key Laboratory of Animal Nutrition and Feed Science in South China, Ministry of Agriculture and Rural Affairs, Guangdong Provincial Key Laboratory of Animal Breeding and Nutrition, Institute of Animal Science, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China"},{"name":"Jiangxi Province Key Innovation Center of High-Quality and Safe Livestock Production, Jiangxi Province Key Laboratory of Animal Nutrition, Engineering Research Center of Feed Development, Jiangxi Agricultural University, Nanchang 330045, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"visualization","vocabulary":"credit"},{"role":"resources","vocabulary":"credit"},{"role":"validation","vocabulary":"credit"},{"role":"methodology","vocabulary":"credit"},{"role":"formal-analysis","vocabulary":"credit"},{"role":"writing-original-draft","vocabulary":"credit"},{"role":"investigation","vocabulary":"credit"},{"role":"supervision","vocabulary":"credit"},{"role":"conceptualization","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"},{"role":"project-administration","vocabulary":"credit"},{"role":"software","vocabulary":"credit"},{"role":"data-curation","vocabulary":"credit"}]},{"given":"Xuebing","family":"Huang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Swine and Poultry Breeding Industry, Key Laboratory of Animal Nutrition and Feed Science in South China, Ministry of Agriculture and Rural Affairs, Guangdong Provincial Key Laboratory of Animal Breeding and Nutrition, Institute of Animal Science, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"visualization","vocabulary":"credit"},{"role":"resources","vocabulary":"credit"},{"role":"validation","vocabulary":"credit"},{"role":"formal-analysis","vocabulary":"credit"},{"role":"supervision","vocabulary":"credit"},{"role":"conceptualization","vocabulary":"credit"},{"role":"data-curation","vocabulary":"credit"}]},{"given":"Weiguang","family":"Xia","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Swine and Poultry Breeding Industry, Key Laboratory of Animal Nutrition and Feed Science in South China, Ministry of Agriculture and Rural Affairs, Guangdong Provincial Key Laboratory of Animal Breeding and Nutrition, Institute of Animal Science, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"supervision","vocabulary":"credit"},{"role":"resources","vocabulary":"credit"},{"role":"project-administration","vocabulary":"credit"},{"role":"investigation","vocabulary":"credit"}]},{"given":"Kaichao","family":"Li","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Swine and Poultry Breeding Industry, Key Laboratory of Animal Nutrition and Feed Science in South China, Ministry of Agriculture and Rural Affairs, Guangdong Provincial Key Laboratory of Animal Breeding and Nutrition, Institute of Animal Science, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"data-curation","vocabulary":"credit"},{"role":"resources","vocabulary":"credit"}]},{"given":"Yanan","family":"Zhang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Swine and Poultry Breeding Industry, Key Laboratory of Animal Nutrition and Feed Science in South China, Ministry of Agriculture and Rural Affairs, Guangdong Provincial Key Laboratory of Animal Breeding and Nutrition, Institute of Animal Science, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"resources","vocabulary":"credit"},{"role":"data-curation","vocabulary":"credit"}]},{"given":"Shuang","family":"Wang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Swine and Poultry Breeding Industry, Key Laboratory of Animal Nutrition and Feed Science in South China, Ministry of Agriculture and Rural Affairs, Guangdong Provincial Key Laboratory of Animal Breeding and Nutrition, Institute of Animal Science, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"resources","vocabulary":"credit"},{"role":"data-curation","vocabulary":"credit"}]},{"given":"Wei","family":"Chen","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Swine and Poultry Breeding Industry, Key Laboratory of Animal Nutrition and Feed Science in South China, Ministry of Agriculture and Rural Affairs, Guangdong Provincial Key Laboratory of Animal Breeding and Nutrition, Institute of Animal Science, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"funding-acquisition","vocabulary":"credit"},{"role":"project-administration","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"},{"role":"resources","vocabulary":"credit"}]},{"given":"Shenglin","family":"Wang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Swine and Poultry Breeding Industry, Key Laboratory of Animal Nutrition and Feed Science in South China, Ministry of Agriculture and Rural Affairs, Guangdong Provincial Key Laboratory of Animal Breeding and Nutrition, Institute of Animal Science, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"resources","vocabulary":"credit"},{"role":"data-curation","vocabulary":"credit"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1967-9477","authenticated-orcid":false,"given":"Chuntian","family":"Zheng","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Swine and Poultry Breeding Industry, Key Laboratory of Animal Nutrition and Feed Science in South China, Ministry of Agriculture and Rural Affairs, Guangdong Provincial Key Laboratory of Animal Breeding and Nutrition, Institute of Animal Science, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"resources","vocabulary":"credit"},{"role":"project-administration","vocabulary":"credit"},{"role":"funding-acquisition","vocabulary":"credit"}]}],"member":"1968","published-online":{"date-parts":[[2026,9,13]]},"reference":[{"key":"ref_1","first-page":"292","article-title":"Modeling the effect of different dose of selenium additives in compound feed on the efficiency of broiler chicken growth","volume":"11","author":"Sobolev","year":"2021","journal-title":"Ukr. J. Ecol."},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Mariotti, M., Ridge, P.G., Zhang, Y., Lobanov, A.V., Pringle, T.H., Guigo, R., Hatfield, D.L., and Gladyshev, V.N. (2012). Composition and evolution of the vertebrate and mammalian selenoproteomes. PLoS ONE, 7.","DOI":"10.1371\/journal.pone.0033066"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"4231","DOI":"10.3382\/ps\/pey406","article-title":"Nutritional modulation of the antioxidant capacities in poultry: The case of selenium","volume":"98","author":"Surai","year":"2019","journal-title":"Poult. Sci."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"798","DOI":"10.3923\/ijps.2008.798.805","article-title":"Selenium Yeast Effect on Broiler Performance","volume":"7","author":"Upton","year":"2008","journal-title":"Int. J. Poult. Sci."},{"key":"ref_5","first-page":"662","article-title":"Effects of different selenium sources selenium supplemental levels on growth performance slaughter performance meat quality breast muscle selenium content of geese","volume":"31","author":"Ju","year":"2019","journal-title":"Chin. J. Anim. Nutr."},{"key":"ref_6","doi-asserted-by":"crossref","unstructured":"Ye, R., Huang, J., Wang, Z., Chen, Y., and Dong, Y. (2022). The Role and Mechanism of Essential Selenoproteins for Homeostasis. Antioxidants, 11.","DOI":"10.3390\/antiox11050973"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"6045","DOI":"10.1016\/j.psj.2020.07.043","article-title":"Selenium-enriched Saccharomyces cerevisiae improves the meat quality of broiler chickens via activation of the glutathione and thioredoxin systems","volume":"99","author":"Hou","year":"2020","journal-title":"Poult. Sci."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"108961","DOI":"10.1016\/j.meatsci.2022.108961","article-title":"Different dietary sources of selenium alter meat quality, shelf life, selenium deposition, and antioxidant status in Hu lambs","volume":"194","author":"Bai","year":"2022","journal-title":"Meat Sci."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1046\/j.1523-5408.2002.00006.x","article-title":"Selenium, an antioxidant nutrient","volume":"5","author":"Burk","year":"2002","journal-title":"Nutr. Clin. Care"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1093\/ps\/86.4.727","article-title":"Effect of Source and Concentration of Selenium on Growth Performance and Selenium Retention in Broiler Chickens","volume":"86","author":"Yoon","year":"2007","journal-title":"Poult. Sci."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"100263","DOI":"10.1016\/j.phanu.2021.100263","article-title":"Selenium supplementation and oxidative stress: A review","volume":"17","author":"Zakeri","year":"2021","journal-title":"Pharmanutrition"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"9769","DOI":"10.1021\/jf902411c","article-title":"Effects of dietary selenomethionine supplementation on growth performance, meat quality and antioxidant property in yellow broilers","volume":"57","author":"Jiang","year":"2009","journal-title":"J. Agric. Food. Chem."},{"key":"ref_13","unstructured":"Bruneel, B. (2020). L-Selenomethionine, Key Component of a Selenized Yeast Feed Additive, Orffa Additives B.V.. Available online: https:\/\/orffa.com\/publications\/l-selenomethionine-key-component-of-a-selenized-yeast-feed-additive\/."},{"key":"ref_14","doi-asserted-by":"crossref","unstructured":"Li, X., Shi, L., Song, P., Cai, W., Luo, X., and Zhao, B. (2024). Certification of New Selenium-Enriched Yeast and Supplement Reference Materials for Selenomethionine Using Two Independent Measurement Strategies. Molecules, 29.","DOI":"10.3390\/molecules29010235"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"2618","DOI":"10.1897\/05-572R.1","article-title":"Selenium absorption, distribution, and excretion in white sturgeon orally dosed with L-selenomethionine","volume":"25","author":"Tashjian","year":"2006","journal-title":"Environ. Toxicol. Chem."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1016\/j.jnutbio.2012.04.008","article-title":"Methylselenol, a selenium metabolite, modulates p53 pathway and inhibits the growth of colon cancer xenografts in Balb\/c mice","volume":"24","author":"Zeng","year":"2013","journal-title":"J. Nutr. Biochem."},{"key":"ref_17","first-page":"7","article-title":"New generation of organic selenium for animal nutrition","volume":"13","author":"Rovers","year":"2014","journal-title":"Int. Dairy Top."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"127235","DOI":"10.1016\/j.jtemb.2023.127235","article-title":"Toxicity of repeated oral intake of organic selenium, inorganic selenium, and selenium nanoparticles: A review","volume":"79","author":"Hadrup","year":"2023","journal-title":"J. Trace Elem. Med. Biol."},{"key":"ref_19","doi-asserted-by":"crossref","unstructured":"Deng, S., Hu, S., Xue, J., Yang, K., Zhuo, R., Xiao, Y., and Fang, R. (2022). Productive Performance, Serum Antioxidant Status, Tissue Selenium Deposition, and Gut Health Analysis of Broiler Chickens Supplemented with Selenium and Probiotics\u2014A Pilot Study. Animals, 12.","DOI":"10.3390\/ani12091086"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/S1043-4526(03)47002-2","article-title":"The nutritional significance, metabolism and toxicology of selenomethionine","volume":"47","author":"Schrauzer","year":"2003","journal-title":"Adv. Food Nutr. Res."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"965","DOI":"10.3382\/ps\/pev045","article-title":"Comparative study of DL-selenomethionine vs. sodium selenite and seleno-yeast on antioxidant activity and selenium status in laying hens","volume":"94","author":"Jing","year":"2015","journal-title":"Poult. Sci."},{"key":"ref_22","first-page":"2882","article-title":"In vitro and in vivo studies of methylseleninic acid: Evidence that a monomethylated selenium metabolite is critical for cancer chemoprevention","volume":"60","author":"Ip","year":"2000","journal-title":"Cancer Res."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"1733","DOI":"10.1038\/bjc.2014.85","article-title":"Se-methylselenocysteine offers selective protection against toxicity and potentiates the antitumour activity of anticancer drugs in preclinical animal models","volume":"110","author":"Cao","year":"2014","journal-title":"Br. J. Cancer"},{"key":"ref_24","first-page":"1471","article-title":"Exploring the Effect of L-Se-methylselenocysteine on Esophageal Cancer Cells EC9706 Based on the PI3K\/AKT Signaling Pathway","volume":"42","author":"Ji","year":"2025","journal-title":"Chin. J. Mod. Appl. Pharm."},{"key":"ref_25","doi-asserted-by":"crossref","unstructured":"Yao, M., Wang, B., Li, Z., Wu, S., Zhao, B., Sun, N., Xiao, H., Wang, J., Liu, G., and Huang, T. (2025). Se-methylselenocysteine inhibits inflammatory response in an LPS-stimulated chicken HD11 macrophage-like cell model through the NFKB2 pathway. Front. Vet. Sci., 11.","DOI":"10.3389\/fvets.2024.1503436"},{"key":"ref_26","unstructured":"National Research Council (1994). Nutrient Requirements of Poultry, National Academies Press. [9th rev. ed.]."},{"key":"ref_27","unstructured":"(2004). Feeding Standard of Chicken (Standard No. NY\/T 33-2004)."},{"key":"ref_28","unstructured":"(2018). Determination of Crude Protein in Feeds\u2014Kjeldahl Method (Standard No. GB\/T 6432-2018)."},{"key":"ref_29","unstructured":"(2019). Determination of Amino Acids in Feeds (Standard No. GB\/T 18246-2019)."},{"key":"ref_30","unstructured":"(2017). Determination of Calcium, Copper, Iron, Magnesium, Manganese, Potassium, Sodium, and Zinc in Feeds\u2014Atomic Absorption Spectrometry (Standard No. GB\/T 13885-2017)."},{"key":"ref_31","unstructured":"(2018). Determination of Phosphorus in Feeds\u2014Spectrophotometry (Standard No. GB\/T 6437-2018)."},{"key":"ref_32","unstructured":"(2008). Determination of Selenium in Feeds (Standard No. GB\/T 13883-2008)."},{"key":"ref_33","first-page":"87","article-title":"China Feed Composition and Nutritional Value Table (31st Edition, 2020)","volume":"21","author":"Xiong","year":"2020","journal-title":"China Feed."},{"key":"ref_34","unstructured":"(2017). National Food Safety Standard\u2014Determination of Selenium in Foods (Standard No. GB\/T 5009.93-2017)."},{"key":"ref_35","unstructured":"American Veterinary Medical Association (2020). AVMA Guidelines for the Euthanasia of Animals: 2020 Edition, American Veterinary Medical Association. Available online: https:\/\/www.avma.org\/sites\/default\/files\/2020-02\/Guidelines-on-Euthanasia-2020.pdf."},{"key":"ref_36","unstructured":"Ammerman, C.B., Baker, D.H., and Lewis, A.J. (1995). Statistical evaluation of bioavailability assays. Bioavailability of Nutrients for Animals, Academic Press."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1515\/biol-2021-0007","article-title":"Effects of inorganic and organic selenium sources on the growth performance of broilers in China: A meta-analysis","volume":"16","author":"Wei","year":"2021","journal-title":"Open Life Sci."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.aninu.2023.12.013","article-title":"Effect of dietary supplementation of selenium-L-methionine on growth, antioxidant capacity and resistance to nitrite stress of spotted seabass (Lateolabrax maculatus) under two rearing water temperatures","volume":"19","author":"Li","year":"2024","journal-title":"Anim. Nutr."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1080\/00071660400006495","article-title":"Selenium supplementation affects broiler growth performance, meat yield and feather coverage","volume":"45","author":"Choct","year":"2004","journal-title":"Br. Poult. Sci."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.3382\/ps.2008-00207","article-title":"Methionine and selenium yeast supplementation of the maternal diets affects color, water-holding capacity, and oxidative stability of their male offspring meat at the early stage","volume":"88","author":"Wang","year":"2009","journal-title":"Poult. Sci."},{"key":"ref_41","unstructured":"Naylor, A.J., and Choct, M. (2000, January 7\u20139). Effects of selenium source and level on performance, mortality and meat quality in male broilers. Proceedings of the 12th Australian Poultry Science Symposium, Sydney, Australia. Available online: https:\/\/hdl.handle.net\/1959.11\/17473."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1007\/s11259-021-09867-3","article-title":"Effects of bacterial organic selenium, selenium yeast and sodium selenite on antioxidant enzymes activity, serum biochemical parameters, and selenium concentration in Lohman brown-classic hens","volume":"46","author":"Muhammad","year":"2022","journal-title":"Vet. Res. Commun."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"215","DOI":"10.4314\/sajas.v50i2.5","article-title":"Selenium and nano-selenium ameliorations in two breeds of broiler chickens exposed to heat stress","volume":"50","author":"Hassan","year":"2020","journal-title":"S. Afr. J. Anim. Sci."},{"key":"ref_44","doi-asserted-by":"crossref","unstructured":"Shen, L., Ma, J., Zhou, H., Chen, L., Tang, J., Zhang, K., Zhao, Y., Niu, L., Zhang, S., and Jiang, A. (2022). Plasma Metabolomic Profiling Reveals Preliminary Biomarkers of Pork Quality Based on pH Value. Foods, 11.","DOI":"10.3390\/foods11244005"},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"111381","DOI":"10.1016\/j.colsurfb.2020.111381","article-title":"Effect of high dose of selenium nanoparticles on antioxidant system and biochemical profile of rats in correction of carbon tetrachloride-induced toxic damage of liver","volume":"197","author":"Lesnichaya","year":"2021","journal-title":"Colloids Surf. B Biointerfaces"},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.anifeedsci.2006.03.020","article-title":"Effects of different selenium source on selenium distribution, loin quality and antioxidant status in finishing pigs","volume":"132","author":"Zhan","year":"2007","journal-title":"Anim. Feed Sci. Technol."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"1566","DOI":"10.5713\/ab.21.0564","article-title":"Effects of dietary methyl sulfonyl methane and selenium on laying performance, egg quality, gut health indicators, and antioxidant capacity of laying hens","volume":"35","author":"Kim","year":"2022","journal-title":"Anim. Biosci."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/j.anifeedsci.2007.10.012","article-title":"Effect of different selenium source (sodium selenite and selenium yeast) on broiler chickens","volume":"144","author":"Wang","year":"2008","journal-title":"Anim. Feed Sci. Technol."},{"key":"ref_49","doi-asserted-by":"crossref","unstructured":"Zhang, X., Tian, L., Zhai, S., Lin, Z., Yang, H., Chen, J., Ye, H., Wang, W., Yang, L., and Zhu, Y. (2020). Effects of Selenium-Enriched Yeast on Performance, Egg Quality, Antioxidant Balance, and Egg Selenium Content in Laying Ducks. Front. Vet. Sci., 7.","DOI":"10.3389\/fvets.2020.00591"},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"3763","DOI":"10.3382\/ps\/pez066","article-title":"Dietary selenomethionine increases antioxidant capacity of geese by improving glutathione and thioredoxin systems","volume":"98","author":"Wan","year":"2019","journal-title":"Poult. Sci."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1080\/00071660020009225","article-title":"Effects of continuous supplementations of ascorbic acid, aspirin, vitamin E and selenium on some haematological parameters and serum superoxide dismutase level in broiler chickens","volume":"41","author":"Tras","year":"2000","journal-title":"Br. Poult. Sci."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"305","DOI":"10.17221\/1296-CJAS","article-title":"Effects of selenomethionine and sodium selenite supplementation on meat quality, selenium distribution and antioxidant status in broilers","volume":"56","author":"Wang","year":"2011","journal-title":"Czech J. Anim. Sci."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/S2095-3119(20)63432-3","article-title":"Effects of selenium source and level on growth performance, antioxidative ability and meat quality of broilers","volume":"20","author":"Wang","year":"2021","journal-title":"J. Integr. Agric."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1080\/00071668.2020.1782350","article-title":"The effect of feeding different sources and levels of selenium on growth performance and antioxidant status of broilers raised at two different temperatures","volume":"61","author":"Woods","year":"2020","journal-title":"Br. Poult. Sci."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.livsci.2014.10.003","article-title":"Effect of dietary organic selenium on milk selenium concentration and antioxidant and immune status in midlactation dairy cows","volume":"170","author":"Gong","year":"2014","journal-title":"Livest. Sci."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"4273","DOI":"10.1007\/s12011-020-02532-x","article-title":"Effect of Glycine Nano-Selenium Supplementation on Production Performance, Egg Quality, Serum Biochemistry, Oxidative Status, and the Intestinal Morphology and Absorption of Laying Hens","volume":"199","author":"Zhou","year":"2021","journal-title":"Biol. Trace Elem. Res."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"339","DOI":"10.2754\/avb200372030339","article-title":"Chicken selenium status when fed a diet supplemented with Se-yeast","volume":"72","author":"Levkut","year":"2003","journal-title":"Acta Vet. Brno"},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1111\/jpn.12571","article-title":"Selenium-enriched Saccharomyces cerevisiae improves growth, antioxidant status and selenoprotein gene expression in Arbor Acres broilers","volume":"101","author":"Chen","year":"2017","journal-title":"J. Anim. Physiol. Anim. Nutr."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"107040","DOI":"10.1016\/j.intimp.2020.107040","article-title":"Suppression of lipopolysaccharide-induced activation of RAW 264.7 macrophages by Se-methylseleno-l-cysteine","volume":"89","author":"Wang","year":"2020","journal-title":"Int. Immunopharmacol."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.2527\/jas.2006-067","article-title":"Efficacy of dietary selenium sources on growth and carcass characteristics of growing-finishing pigs fed diets containing high endogenous selenium","volume":"85","author":"Mateo","year":"2007","journal-title":"J. Anim. Sci."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"306","DOI":"10.17221\/358-CJAS","article-title":"Effect of dietary selenium on lipid oxidation, selenium and vitamin E content in the meat of broiler chickens","volume":"53","author":"Skrivan","year":"2008","journal-title":"Czech J. Anim. Sci."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"617","DOI":"10.2527\/2002.803617x","article-title":"Correlations among selected pork quality traits","volume":"80","author":"Baas","year":"2002","journal-title":"J. Anim. Sci."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"104562","DOI":"10.1016\/j.livsci.2021.104562","article-title":"Effects of selenium-chitosan on growth performance, carcass traits, meat quality, and blood indices of broiler chickens","volume":"250","author":"Bami","year":"2021","journal-title":"Livest. Sci."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"e10","DOI":"10.1017\/jan.2016.8","article-title":"Sel-Plex\u2122, a source of organic selenium in selenised yeast protein, as a factor that influences meat quality","volume":"4","author":"Edens","year":"2016","journal-title":"J. Appl. Anim. Nutr."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"txad49","DOI":"10.1093\/tas\/txad049","article-title":"Evaluation of selenium source on nursery pig growth performance, serum and tissue selenium concentrations, and serum antioxidant status","volume":"7","author":"Rao","year":"2023","journal-title":"Transl. Anim. Sci."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"481","DOI":"10.5194\/aab-67-481-2024","article-title":"Growth performance, carcass characteristics, fatty acid profile, and meat quality of male goat kids supplemented by alternative feed resources: Bitter vetch and sorghum grains","volume":"67","author":"Boukrouh","year":"2024","journal-title":"Arch. Anim. Breed."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.meatsci.2010.09.011","article-title":"Phenotypic blood glutathione concentration and selenium supplementation interactions on meat colour stability and fatty acid concentrations in Merino lambs","volume":"87","author":"Liu","year":"2011","journal-title":"Meat Sci."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1093\/ps\/84.5.809","article-title":"Effects of different levels of dietary supplemental selenium on performance, lipid oxidation, and color stability of broiler chicks","volume":"84","author":"Ryu","year":"2005","journal-title":"Poult. Sci."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"1531","DOI":"10.1017\/S1751731111000711","article-title":"Effect of dietary supplementation with different sources of selenium on growth response, selenium blood levels and meat quality of intensively finished Charolais young bulls","volume":"5","author":"Cozzi","year":"2011","journal-title":"Animal"},{"key":"ref_70","doi-asserted-by":"crossref","unstructured":"Liu, J., Wang, Z., Li, C., Chen, Z., Zheng, A., Chang, W., Liu, G., and Cai, H. (2023). Effects of Selenium Dietary Yeast on Growth Performance, Slaughter Performance, Antioxidant Capacity, and Selenium Deposition in Broiler Chickens. Animals, 13.","DOI":"10.3390\/ani13243830"},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1039\/C5JA00330J","article-title":"Development and application of a selenium speciation method in cattle feed and beef samples using HPLC-ICP-MS: Evaluating the selenium metabolic process in cattle","volume":"31","author":"Oliveira","year":"2016","journal-title":"J. Anal. At. Spectrom."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/S0753-3322(03)00035-0","article-title":"The antioxidant role of selenium and seleno-compounds","volume":"57","author":"Tapiero","year":"2003","journal-title":"Biomed. Pharmacother."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1002\/jmr.2241","article-title":"Characterization of selenium-containing glutathione transferase zeta1-1 with high GPX activity prepared in eukaryotic cells","volume":"26","author":"Yin","year":"2013","journal-title":"J. Mol. Recognit."},{"key":"ref_74","first-page":"3673","article-title":"Effects of Organic Trace Elements on Growth Performance, Slaughter Performance, Meat Quality and Serum Indexes of White-Feather Broilers","volume":"35","author":"Yao","year":"2023","journal-title":"Chin. J. Anim. Nutr."},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1093\/ps\/84.6.898","article-title":"Comparison of inorganic and organic selenium sources for broilers","volume":"84","author":"Payne","year":"2005","journal-title":"Poult. Sci."},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"572","DOI":"10.17221\/2487-CJAS","article-title":"The effect of dietary selenium sources and levels on performance, selenium content in muscle and glutathione peroxidase activity in broiler chickens","volume":"55","author":"Heindl","year":"2010","journal-title":"Czech J. Anim. Sci."}],"container-title":["Animals"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2076-2615\/16\/18\/2882\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T09:57:18Z","timestamp":1789379838000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2076-2615\/16\/18\/2882"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,13]]},"references-count":76,"journal-issue":{"issue":"18","published-online":{"date-parts":[[2026,9]]}},"alternative-id":["ani16182882"],"URL":"https:\/\/doi.org\/10.3390\/ani16182882","relation":{},"ISSN":["2076-2615"],"issn-type":[{"value":"2076-2615","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,13]]}}}