{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T20:09:14Z","timestamp":1791230954165,"version":"4.1.0"},"reference-count":18,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2019,9,29]],"date-time":"2019-09-29T00:00:00Z","timestamp":1569715200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animals"],"abstract":"<jats:p>During the periods January to April, May to August, and September to December in two consecutive years, sows were assigned at breeding to receive semen doses supplemented with 87 \u00b5g cloprostenol (PG; n = 158), 5 IU oxytocin (OT; n = 154), 2 \u00b5g buserelin (GN; n = 93), or served as non-supplemented controls (CON; n = 605). Sows were inseminated at the detection of estrus, and again 24 h later, but only the first inseminations were supplemented. Compared to CON, only buserelin increased pregnancy and farrowing rates (p \u2264 0.05); there was no effect of a period or a treatment \u00d7 period interaction. Litter size was larger (p \u2264 0.001) for all seminal additive groups during the first two periods and tended to increase in GN compared to CON (p \u2264 0.1) during the third period, resulting in a tendency (p &lt; 0.1) for a period \u00d7 treatment interaction. The addition of cloprostenol, oxytocin or buserelin to semen doses at first insemination increases litter size in multiparous sows.<\/jats:p>","DOI":"10.3390\/ani9100746","type":"journal-article","created":{"date-parts":[[2019,9,30]],"date-time":"2019-09-30T05:58:33Z","timestamp":1569823113000},"page":"746","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Effect of Oxytocin, Cloprostenol or Buserelin in Semen Doses on Sow Fertility"],"prefix":"10.3390","volume":"9","author":[{"given":"Rodrigo","family":"Manjar\u00edn","sequence":"first","affiliation":[{"name":"Animal Science Department, California Polytechnic State University, San Luis Obispo, CA 93407-0255, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3294-8301","authenticated-orcid":false,"given":"Roy N.","family":"Kirkwood","sequence":"additional","affiliation":[{"name":"School of Animal and Veterinary Sciences, University of Adelaide, 5371 Roseworthy, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose","family":"Ngula","sequence":"additional","affiliation":[{"name":"Department of Medicine, Surgery and Veterinary Anatomy, Universidad de Le\u00f3n, s\/n, 24071 Le\u00f3n, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2987-4302","authenticated-orcid":false,"given":"Felipe","family":"Martinez-Pastor","sequence":"additional","affiliation":[{"name":"Molecular Biology (Cell Biology), Universidad de Le\u00f3n, s\/n, 24071 Le\u00f3n, Spain"},{"name":"Institute of Animal Health and Pastoral Farming Development, Universidad de Le\u00f3n, s\/n, 24071 Le\u00f3n, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beatrix","family":"Alegre","sequence":"additional","affiliation":[{"name":"Department of Medicine, Surgery and Veterinary Anatomy, Universidad de Le\u00f3n, s\/n, 24071 Le\u00f3n, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Carlos","family":"Dom\u00ednguez","sequence":"additional","affiliation":[{"name":"Department of Medicine, Surgery and Veterinary Anatomy, Universidad de Le\u00f3n, s\/n, 24071 Le\u00f3n, Spain"},{"name":"Institute of Animal Health and Pastoral Farming Development, Universidad de Le\u00f3n, s\/n, 24071 Le\u00f3n, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2019,9,29]]},"reference":[{"key":"ref_1","first-page":"117","article-title":"Physiological role of seminal components in the reproductive tract of the female pig","volume":"40","author":"Claus","year":"1990","journal-title":"J. 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