{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T01:02:16Z","timestamp":1792112536628,"version":"4.4.0"},"reference-count":52,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"VEGA projects","award":["2\/0061\/17"],"award-info":[{"award-number":["2\/0061\/17"]}]},{"name":"VEGA Project","award":["2\/0059\/19"],"award-info":[{"award-number":["2\/0059\/19"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Antibiotics"],"abstract":"<jats:p>Nanotechnology is a new frontier of this century that finds applications in various fields of science with important effects on our life and on the environment. Nanoencapsulation of bioactive compounds is a promising topic of nanotechnology. The excessive use of synthetic compounds with antifungal activity has led to the selection of resistant fungal species. In this context, the use of plant essential oils (EOs) with antifungal activity encapsulated in ecofriendly nanosystems could be a new and winning strategy to overcome the problem. We prepared nanoencapsules containing the essential oils of Origanum vulgare (OV) and Thymus capitatus (TC) by the nanoprecipitation method. The colloidal suspensions were characterized for size, polydispersity index (PDI), zeta potential, efficiency of encapsulation (EE) and loading capacity (LC). Finally, the essential oil nanosuspensions were assayed against a panel of fourteen fungal strains belonging to the Ascomycota and Basidiomycota phyla. Our results show that the nanosystems containing thyme and oregano essential oils were active against various fungal strains from natural environments and materials. In particular, the minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) values were two to four times lower than the pure essential oils. The aqueous, ecofriendly essential oil nanosuspensions with broad-spectrum antifungal activity could be a valid alternative to synthetic products, finding interesting applications in the agri-food and environmental fields.<\/jats:p>","DOI":"10.3390\/antibiotics10010031","type":"journal-article","created":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T22:35:48Z","timestamp":1609540548000},"page":"31","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":56,"title":["Nanoencapsulated Essential Oils with Enhanced Antifungal Activity for Potential Application on Agri-Food, Material and Environmental Fields"],"prefix":"10.3390","volume":"10","author":[{"given":"Magdal\u00e9na","family":"Kapustov\u00e1","sequence":"first","affiliation":[{"name":"Institute of Molecular Biology, Slovak Academy of Sciences, D\u00fabravsk\u00e1 cesta 21, 84551 Bratislava, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9428-3985","authenticated-orcid":false,"given":"Giuseppe","family":"Granata","sequence":"additional","affiliation":[{"name":"Istituto Chimica Biomolecolare\u2013Consiglio Nazionale delle Ricerche, Via Paolo Gaifami 18, 95126 Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4281-3256","authenticated-orcid":false,"given":"Edoardo","family":"Napoli","sequence":"additional","affiliation":[{"name":"Istituto Chimica Biomolecolare\u2013Consiglio Nazionale delle Ricerche, Via Paolo Gaifami 18, 95126 Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Pu\u0161k\u00e1rov\u00e1","sequence":"additional","affiliation":[{"name":"Institute of Molecular Biology, Slovak Academy of Sciences, D\u00fabravsk\u00e1 cesta 21, 84551 Bratislava, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00e1ria","family":"Bu\u010dkov\u00e1","sequence":"additional","affiliation":[{"name":"Institute of Molecular Biology, Slovak Academy of Sciences, D\u00fabravsk\u00e1 cesta 21, 84551 Bratislava, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9115-9409","authenticated-orcid":false,"given":"Domenico","family":"Pangallo","sequence":"additional","affiliation":[{"name":"Institute of Molecular Biology, Slovak Academy of Sciences, D\u00fabravsk\u00e1 cesta 21, 84551 Bratislava, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5850-0372","authenticated-orcid":false,"given":"Corrada","family":"Geraci","sequence":"additional","affiliation":[{"name":"Istituto Chimica Biomolecolare\u2013Consiglio Nazionale delle Ricerche, Via Paolo Gaifami 18, 95126 Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,1,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.fbr.2010.03.003","article-title":"Fungi: Their role in deterioration of cultural heritage","volume":"24","author":"Sterflinger","year":"2010","journal-title":"Fungal Biol. 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