{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T18:27:05Z","timestamp":1775327225851,"version":"3.50.1"},"reference-count":31,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2021,4,13]],"date-time":"2021-04-13T00:00:00Z","timestamp":1618272000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"JAPAN SOCIETY FOR THE PROMOTION OF SCIENCE","award":["18H04073"],"award-info":[{"award-number":["18H04073"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Antibiotics"],"abstract":"<jats:p>Antimicrobial-resistant (AMR) bacteria affect human and animal health worldwide. Here, CTX-M-14-producing Escherichia coli isolates were isolated from Siberian weasels (Mustela sibirica) that were captured on a veterinary campus. To clarify the source of bacteria in the weasels, we examined the domestic animals reared in seven facilities on the campus. Extended-spectrum \u03b2-lactamase (ESBL)-producing E. coli were isolated on deoxycholate hydrogen sulfide lactose agar, containing cephalexin (50 \u03bcg\/mL) or cefotaxime (2 \u03bcg\/mL), and were characterized with antimicrobial susceptibility testing, pulsed-field gel electrophoresis (PFGE), replicon typing, and \u03b2-lactamase typing analyses. Next-generation sequencing of the ESBL-encoding plasmids was also performed. CTX-M-14 producers isolated from both domestic animals and weasels were classified into six clusters with seven PFGE profiles. The PFGE and antimicrobial resistance profiles were characterized by the animal facility. All CTX-M-14 plasmids belonged to the IncI1 type with a similar size (98.9\u201399.3 kb), except for one plasmid that was 105.5 kb in length. The unweighted pair group method with arithmetic mean (UPGMA) revealed that the CTX-M-14 plasmid in the weasel isolates might have the same origin as the CTX-M-14 plasmid in the domestic animals. Our findings shed further light on the association of antimicrobial resistance between wild and domestic animals.<\/jats:p>","DOI":"10.3390\/antibiotics10040432","type":"journal-article","created":{"date-parts":[[2021,4,13]],"date-time":"2021-04-13T10:58:07Z","timestamp":1618311487000},"page":"432","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Association between the blaCTX-M-14-harboring Escherichia coli Isolated from Weasels and Domestic Animals Reared on a University Campus"],"prefix":"10.3390","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3985-0072","authenticated-orcid":false,"given":"Montira","family":"Yossapol","sequence":"first","affiliation":[{"name":"Department of Applied Veterinary Science, United Graduate School of Veterinary Sciences, Gifu University, Gifu 5011193, Japan"},{"name":"Bioveterinary Research Unit, Faculty of Veterinary Sciences, Mahasarakham University, Maha Sarakham 44000, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miku","family":"Yamamoto","sequence":"additional","affiliation":[{"name":"Department of Applied Veterinary Science, United Graduate School of Veterinary Sciences, Gifu University, Gifu 5011193, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michiyo","family":"Sugiyama","sequence":"additional","affiliation":[{"name":"Department of Applied Veterinary Science, United Graduate School of Veterinary Sciences, Gifu University, Gifu 5011193, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4109-1215","authenticated-orcid":false,"given":"Justice Opare","family":"Odoi","sequence":"additional","affiliation":[{"name":"Department of Applied Veterinary Science, United Graduate School of Veterinary Sciences, Gifu University, Gifu 5011193, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tsutomu","family":"Omatsu","sequence":"additional","affiliation":[{"name":"Research and Education Center for Prevention of Global Infectious Diseases of Animals, Tokyo University of Agriculture and Technology, Tokyo 1838538, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tetsuya","family":"Mizutani","sequence":"additional","affiliation":[{"name":"Research and Education Center for Prevention of Global Infectious Diseases of Animals, Tokyo University of Agriculture and Technology, Tokyo 1838538, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8867-3618","authenticated-orcid":false,"given":"Kenji","family":"Ohya","sequence":"additional","affiliation":[{"name":"Department of Applied Veterinary Science, United Graduate School of Veterinary Sciences, Gifu University, Gifu 5011193, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6556-9674","authenticated-orcid":false,"given":"Tetsuo","family":"Asai","sequence":"additional","affiliation":[{"name":"Department of Applied Veterinary Science, United Graduate School of Veterinary Sciences, Gifu University, Gifu 5011193, Japan"},{"name":"Education and Research Center for Food Animal Health, Gifu University, Gifu 5011193, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,4,13]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Woolhouse, M., Ward, M., van Bunnik, B., and Farrar, J. 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