{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T17:42:29Z","timestamp":1783186949889,"version":"3.54.6"},"reference-count":17,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2021,6,11]],"date-time":"2021-06-11T00:00:00Z","timestamp":1623369600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Antibiotics"],"abstract":"<jats:p>The aim of this study was to analyze the antibiotics prescription habits, both prophylactically and therapeutically, of Spanish general dental practitioners in the management of endodontic infections in primary care. Two hundred Spanish general dental practitioners were asked to respond to a survey on indications for antibiotics prescription in the treatment of endodontic infections, being 190 general dentists (95%) included in the study. Data were analyzed using descriptive statistics and the chi-square test. The average duration of antibiotics therapy was 6.5 \u00b1 1.0 days. In patients without medical allergies, most of them (97%) selected amoxicillin as the antibiotic of the first choice, alone (51.1%) or associated with clavulanic acid (45.8%); in patients with penicillin allergies, the drug of choice was clindamycin 300 mg (70%). For cases of symptomatic irreversible pulpitis, 44% of the respondents prescribed antibiotics, in the scenario of prophylactic antibiotic prescription, up to 27% of the general dentists prescribe according to non-current guidelines (1 g 1 h before or 1 g 1 h before and 1 g 1 h after) in non-indicated cases (16% in patients taking oral bisphosphonates). It is necessary to improve the antibiotic prescription habits of Spanish general dentists in endodontics.<\/jats:p>","DOI":"10.3390\/antibiotics10060703","type":"journal-article","created":{"date-parts":[[2021,6,11]],"date-time":"2021-06-11T12:44:37Z","timestamp":1623415477000},"page":"703","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Antibiotics Prescription by Spanish General Practitioners in Primary Dental Care"],"prefix":"10.3390","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-2632-7684","authenticated-orcid":false,"given":"Laura","family":"Dom\u00ednguez-Dom\u00ednguez","sequence":"first","affiliation":[{"name":"Endodontic Section, Department of Stomatology, University of Sevilla, C\/Avicena s\/n, 41009 Sevilla, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfonso","family":"L\u00f3pez-Marrufo-Medina","sequence":"additional","affiliation":[{"name":"Endodontic Section, Department of Stomatology, University of Sevilla, C\/Avicena s\/n, 41009 Sevilla, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9978-6458","authenticated-orcid":false,"given":"Daniel","family":"Cabanillas-Balsera","sequence":"additional","affiliation":[{"name":"Endodontic Section, Department of Stomatology, University of Sevilla, C\/Avicena s\/n, 41009 Sevilla, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda Carmen","family":"Jim\u00e9nez-S\u00e1nchez","sequence":"additional","affiliation":[{"name":"Endodontic Section, Department of Stomatology, University of Sevilla, C\/Avicena s\/n, 41009 Sevilla, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6207-8880","authenticated-orcid":false,"given":"Victoria","family":"Areal-Quecuty","sequence":"additional","affiliation":[{"name":"Endodontic Section, Department of Stomatology, University of Sevilla, C\/Avicena s\/n, 41009 Sevilla, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8035-4412","authenticated-orcid":false,"given":"Jos\u00e9","family":"L\u00f3pez-L\u00f3pez","sequence":"additional","affiliation":[{"name":"Department of Odontostomatology, Faculty of Medicine and Health Sciences (Dentistry), Barcelona University Dental Hospital, University of Barcelona, 08007 Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0427-9059","authenticated-orcid":false,"given":"Juan. J.","family":"Segura-Egea","sequence":"additional","affiliation":[{"name":"Endodontic Section, Department of Stomatology, University of Sevilla, C\/Avicena s\/n, 41009 Sevilla, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jenifer","family":"Martin-Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Endodontic Section, Department of Stomatology, University of Sevilla, C\/Avicena s\/n, 41009 Sevilla, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,6,11]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1016\/j.joen.2009.05.031","article-title":"Antibiotic Use by Members of the Spanish Endodontic Society","volume":"35","year":"2009","journal-title":"J. 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Endod., 43, 1409\u20131413.","DOI":"10.1016\/j.joen.2017.08.015"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1016\/S1079-2104(96)80054-0","article-title":"Penicillin as a supplement in resolving the localized acute apical abscess","volume":"81","author":"Fouad","year":"1996","journal-title":"Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.1111\/j.1365-2591.2009.01642.x","article-title":"Antibiotic prescribing in dental practice in Belgium","volume":"42","author":"Mainjot","year":"2009","journal-title":"Int. Endod. J."},{"key":"ref_15","first-page":"83","article-title":"The Pattern of Antibiotic Prescribing by Dental Practitioners in Zagreb, Croatia","volume":"23","author":"Simeon","year":"2015","journal-title":"Cent. Eur. J. Public Health"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"806","DOI":"10.3390\/medicina46120113","article-title":"Antibiotic prescription for the treatment of endodontic pathology: A survey among Lithuanian dentists","volume":"46","year":"2010","journal-title":"Medicina"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/S0099-2399(06)81631-6","article-title":"Treatment of the endodontic emergency: A decade later","volume":"16","author":"Gatewood","year":"1990","journal-title":"J. Endod."}],"container-title":["Antibiotics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2079-6382\/10\/6\/703\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T06:13:20Z","timestamp":1760163200000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2079-6382\/10\/6\/703"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6,11]]},"references-count":17,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2021,6]]}},"alternative-id":["antibiotics10060703"],"URL":"https:\/\/doi.org\/10.3390\/antibiotics10060703","relation":{},"ISSN":["2079-6382"],"issn-type":[{"value":"2079-6382","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,6,11]]}}}