{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T14:20:29Z","timestamp":1775830829335,"version":"3.50.1"},"reference-count":28,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2022,1,11]],"date-time":"2022-01-11T00:00:00Z","timestamp":1641859200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Antibiotics"],"abstract":"<jats:p>Chronic bacterial prostatitis is increasingly difficult to treat due to rising antimicrobial resistance limiting oral treatment options. In this case series, 11 men with CBP (including patients with urological comorbidities) due to multi-resistant E. coli were treated with once-daily ceftriaxone intravenously for 6 weeks. Nine patients were clinically cured at 3 months follow up. No early withdrawal of medication due to side effects occurred. A literature review was conducted to describe the prostate pharmacokinetics of ceftriaxone and its use in prostatic infection. In conclusion, ceftriaxone can be considered an appropriate treatment of chronic bacterial prostatitis.<\/jats:p>","DOI":"10.3390\/antibiotics11010083","type":"journal-article","created":{"date-parts":[[2022,1,11]],"date-time":"2022-01-11T14:05:07Z","timestamp":1641909907000},"page":"83","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Ceftriaxone for the Treatment of Chronic Bacterial Prostatitis: A Case Series and Literature Review"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8426-2221","authenticated-orcid":false,"given":"Sander G.","family":"Kuiper","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Haga Teaching Hospital, 2545 AA The Hague, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maarten","family":"Ploeger","sequence":"additional","affiliation":[{"name":"Department of Hospital Pharmacy, Haga Teaching Hospital, 2545 AA The Hague, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erik B.","family":"Wilms","sequence":"additional","affiliation":[{"name":"Department of Hospital Pharmacy, Haga Teaching Hospital, 2545 AA The Hague, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marleen M.","family":"van Dijk","sequence":"additional","affiliation":[{"name":"Department of Urology, Haga Teaching Hospital, 2545 AA The Hague, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emiel","family":"Leegwater","sequence":"additional","affiliation":[{"name":"Department of Hospital Pharmacy, Haga Teaching Hospital, 2545 AA The Hague, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert A. G.","family":"Huis in\u2019t Veld","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology, University of Groningen, University Medical Center Groningen, 9713 GZ Groningen, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0734-0844","authenticated-orcid":false,"given":"Cees","family":"van Nieuwkoop","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Haga Teaching Hospital, 2545 AA The Hague, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,1,11]]},"reference":[{"key":"ref_1","unstructured":"Bjerklund Johansen, T.E., Wagenlehner, F.M.E., Matsumoto, T., Cho, Y.H., Krieger, J.N., Shoskes, D., and Naber, K.G. (2017). Treatment of chronic bacterial prostatitis. 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